Zhiyuan Xu

Stereotactic Radiosurgery Dose Reduction for Patients With Brain Metastases From Non–Small Cell Lung Primary on Immunotherapy or Targeted Therapy

Jared H. Chung, Salem M Tos, Georgios Mantziaris, Yuki Shinya et autres

BACKGROUND AND OBJECTIVES: Lung cancer is the most common primary neoplasm that metastasizes to the brain. Although stereotactic radiosurgery (SRS) using American Society for Radiation Oncology guideline-suggested doses improves local control, it may increase adverse radiation events (AREs). This study evaluates whether …

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RADT-73. IMPACT OF AGE-RELATED AND CLINICAL RISK FACTORS ON SURVIVAL IN TRIPLE NEGATIVE BREAST CANCER PATIENTS WITH BRAIN METASTASES TREATED WITH STEREOTACTIC RADIOSURGERY

Zhiyuan Xu

Abstract BACKGROUND Triple-negative breast cancer (TNBC) carries a high risk of brain metastases and poor prognosis. The impact of estrogen-related factors, such as age at breast cancer diagnosis, on survival in this setting remains underexplored. Clinical variables, including extracranial disease and comorbidities, …

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Outcomes After Stereotactic Radiosurgery for Intracranial Hemangioblastoma in Von Hippel-Lindau Disease and Sporadic Cases: An International Multicenter Study

Ahmed A. Shaaban, Salem M Tos, Georgios Mantziaris, D. T. Pham et autres

BACKGROUND AND OBJECTIVES: Hemangioblastomas (HGBs) are rare, benign, World Health Organization grade 1 vascular tumors, which are most commonly located in the cerebellum, and may occur sporadically or in association with von Hippel-Lindau (VHL) disease, a hereditary VHL-mutated tumor syndrome. Limited data …

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Comparative analysis of stereotactic radiosurgery outcomes for supratentorial hemangioblastomas in von hippel-lindau disease and sporadic cases: A multi-center international study

Salem M Tos, Bardia Hajikarimloo, Georgios Mantziaris, Ahmed Taha Elsayed Shaaban et autres

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Effect of cerebral arteriovenous malformation location on outcomes of repeat, single-fraction stereotactic radiosurgery: a matched-cohort analysis

Georgios Mantziaris, Stylianos Pikis, Chloé Dumot, Sam Dayawansa et autres

OBJECTIVE: Patients with deep-seated arteriovenous malformations (AVMs) have a higher rate of unfavorable outcome and lower rate of nidus obliteration after primary stereotactic radiosurgery (SRS). The aim of this study was to evaluate and quantify the effect of AVM location on repeat …

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Third Stereotactic Radiosurgery for Residual Arteriovenous Malformations: A Retrospective Multicenter Study

Stylianos Pikis, Georgios Mantziaris, Chloé Dumot, Ahmed Taha Elsayed Shaaban et autres

BACKGROUND AND OBJECTIVES: There are no studies evaluating the efficacy and safety of more than 2 stereotactic radiosurgery (SRS) procedures for cerebral arteriovenous malformations (AVM). The aim of this study was to provide evidence on the role of third single-session SRS for …

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Outcome Evaluation of Repeat Stereotactic Radiosurgery for Cerebral Arteriovenous Malformations

Georgios Mantziaris, Stylianos Pikis, Chloé Dumot, Sam Dayawansa et autres

BACKGROUND: Repeat stereotactic radiosurgery (SRS) for persistent cerebral arteriovenous malformation (AVM) has generally favorable patient outcomes. However, reporting studies are limited by small patient numbers and single-institution biases. The purpose of this study was to provide the combined experience of multiple centers, …

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