Jiayu Wei

RNA G-quadruplexes promote codon repeat-associated ribosomal frameshifting in human genes

Xiuwen Li, Lei Cai, Yingshui Zhou, Shimin Gong et autres

Programmed ribosomal frameshifting (PRF), a translational recoding process previously considered as a rare event in eukaryotes, has recently been demonstrated to occur extensively in humans. We have shown that codon repeats function as the signals for the production of trans-frame proteins in …

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Enterolactone promotes efficacy of gemcitabine on epithelial ovarian cancer and ameliorates gut dysbacteriosis

Danli Cao, Caiji Lin, Jiaxing Wang, Mengzhi Xu et autres

BACKGROUND AND PURPOSE: The effectiveness of conventional treatments for epithelial ovarian cancer (EOC) is very limited and their side effects are serious. Previous research has demonstrated the inhibitory effects of enterolactone (ENL) on EOC by inhibiting malignant angiogenesis. Gemcitabine (Gem) is a …

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The Role of SLC7A11 in Tumor Progression and the Regulation Mechanisms Involved in Ferroptosis

Xizheng Zhang, Yao Zhang, Jiayu Wei, Xuyan Li et autres

), which is crucial for maintaining cellular redox homeostasis (especially glutathione synthesis) and regulating Ferroptosis. It is highly expressed in various malignant tumors and is a key factor leading to treatment resistance, making it an important anti-cancer target. This review systematically summarizes …

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Breaking the MoE LLM Trilemma: Dynamic Expert Clustering with Structured Compression

Ning Yang, Jiayu Wei, Haijun Zhang

Mixture-of-Experts (MoE) Large Language Models (LLMs) face a trilemma of load imbalance, parameter redundancy, and communication overhead. We introduce a unified framework based on dynamic expert clustering and structured compression to address these issues cohesively. Our method employs an online clustering procedure …

Evaluation analysis of college Chinese teaching based on random simulation algorithm

Jiayu Wei

This paper proposes a random simulation-based evaluation model for college Chinese teaching, aiming at accurately evaluating teaching effect and students’ learning progress through comprehensive and detailed evaluation index system, diversified data integration method and advanced Monte Carlo simulation technology. The evaluation system …

Prognostic Factors of Oncologic and Reproductive Outcomes in Conservative Therapy of Endometrial Hyperplasia and Endometrial Cancer: Systematic Review and Meta-Analysis

L. Y. He, Jiayu Wei, Dan Kuai, Dongcan Zhang et autres

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Assessment of suspended atmospheric microplastics in Tianjin Binhai New Area: characterization, human health risks, and correlation with weather conditions and Air Quality Index

Jiayu Wei, Bo Yan, Chunyan Wang, Fengxu Liu et autres

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Super-robust synthetic microorganism can get chlorine resistance in advance and transfer their inserted DNA sequence in genome to indigenous bacteria in water

Xuejing Huang, Zaigao Tan, Jiayu Wei, Xiaohui Bai

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Decentralized control of interconnected systems with actuator faults and disturbances via cooperative interaction observer approach

Xin Huang, Jiayu Wei, Jian Li, Shuyi Xiao et autres

This work investigates decentralised control problems of interconnected systems under actuator faults and disturbances via cooperative interaction observers. Firstly, the influence of faults and matched disturbances is described by an unknown signal generated from any unknown input-to-state stable dynamics. Next, by using …

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Comparative Genomics and Transcriptome Analysis of Two Colletotrichum scovillei Strains Revealed Genes Involved in Pathogenicity on Pepper (Capsicum annuum L.)

Jiayu Wei, Yue Li, Jubin Wang, Xi Zhang et autres

ABSTRACT Colletotrichum scovillei causes anthracnose in chilli pepper worldwide, which is one of the most serious diseases affecting the production of pepper fruits. Although there are several studies on the Colletotrichum disease genes identified, there are still gaps in the understanding of …

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Enterolactone combined with m6A Reader IGF2BP3 inhibits malignant angiogenesis and disease progression in ovarian cancer

Mengzhi Xu, Yi Guo, Fengge Wang, Caiji Lin et autres

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Enterolactone promotes Efficacy of Gemcitabine on Epithelial Ovarian Cancer and ameliorates Gut dysbacteriosis

Danli Cao, Caiji Lin, Jiaxing Wang, Mengzhi Xu et autres

Epithelial ovarian cancer (EOC) is a deadly malignant tumor that impacts the female reproductive system, ranking third in incidence after cervical and endometrial cancers and first in mortality rate among these three major tumors. The conventional treatments include chemotherapy, radiotherapy, and surgery, …

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