Jiuyue Ma

IDDF2026-ABS-0182 ST1A1 attenuates 5-aminosalicylic acid uptake and promotes its metabolism in intestinal epithelial cells through EGFR-MAPK signaling in ulcerative colitis

X Xu, Dan Yan, Jiuyue Ma, Minsi Zhou et autres

Background 5-Aminosalicylic acid (5-ASA) remains the first-line therapy for mild-to-moderate ulcerative colitis (UC). However, only half of the patients exhibit a good response. The mechanisms underlying inter-individual variation in 5-ASA efficacy remain unclear. This study integrated plasma proteomics with mechanistic validation to …

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IDDF2026-ABS-0208 Multi-cohort analysis identifies microbial biomarkers predictive of biologic therapy response in inflammatory bowel disease

Zi Ye, Yan Dang, Chenyue Xu, X Xu et autres

Background Over 40% of patients with inflammatory bowel disease (IBD) fail to respond to biologics, and no reliable biomarkers are currently available to predict treatment response before therapy initiation. Therefore, we aimed to evaluate the potential of gut microbial signatures as predictive …

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Gut microbiome signatures predict 5-ASA efficacy in ulcerative colitis

Yan Dang, Xinyi Xu, Jiuyue Ma, Minsi Zhou et autres

were consistently depleted in the ineffective group at both time points. A random forest model based on these three species predicted ineffective 5-ASA treatment with area under the curve (AUC) = 0.80 (validation in the Inflammatory Bowel Disease Multi'omics Database [IBDMDB]: AUC …

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Mo1901: HIGH LEVEL OF LIFE’S ESSENTIAL 8 INDEX REDUCES LONG-TERM RISK OF COLECTOMY BY AMELIORATING SYSTEMIC INFLAMMATION IN ULCERATIVE COLITIS PATIENTS: A PROSPECTIVE COHORT STUDY

Fang Zhou Xu, Min Zhu, Min Si Zhou, Chen Yue Xu et autres

Sa1902: GUT MICROBIOME SIGNATURES PREDICT 5-ASA EFFICACY IN ULCERATIVE COLITIS

Yan Dang, Xin Yi Xu, Jiuyue Ma, Min Si Zhou et autres

Mo1695: HIGHER LIFE’S ESSENTIAL 8 SCORES PROTECT AGAINST BRAIN INJURY IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE

Chen Yue Xu, Li Yu, Fang Xu, Min Si Zhou et autres

Sa1842: PHYSICAL ACTIVITY REDUCES ALL-CAUSE MORTALITY AND RISK FOR BOWEL SURGERY IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE: A POPULATION-BASED PROSPECTIVE COHORT STUDY

Jiuyue Ma, Min Si Zhou, Yan Dang, Xin Yi Xu et autres

Clinical and pathological characteristics of and predictive model for colorectal neuroendocrine tumors

Jiuyue Ma, Xiaoqian Ma, Jie Xing, Ruyun Song et autres

Background: The incidence of colorectal neuroendocrine tumors (NETs) is increasing, causing a social burden. At present, there is no specific prognostic model for colorectal NETs. Thus, an accurate model is needed to predict the prognosis of patients with colorectal NETs. Aim: We …

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IDDF2024-ABS-0453 Long-term risk of colectomy associated with life’s essential 8 in ulcerative colitis patients: a prospective cohort study

Fang Zhou Xu, Minsi Zhou, Chenyue Xu, Xinyi Xu et autres

Background The activity and severity of ulcerative colitis (UC) are associated with the need for colectomy. Life’s Essential 8 (LE8) index is a novel cardiovascular health measure potentially associated with inflammation. However, its impact on the risk of colectomy in UC patients …

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Clinical and Pathological Characteristics and Predictive Model Building of Colorectal Neuroendocrine Tumors

Jiuyue Ma, Qian Zhang, Jie Xing, Ruyun Song et autres

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OX40 Expression in Eosinophils Aggravates OVA-Induced Eosinophilic Gastroenteritis

Longwei Xu, Dan Tian, Minsi Zhou, Jiuyue Ma et autres

Background & Aims Eosinophils are the main inflammatory effector cells that damage gastrointestinal tissue in eosinophilic gastrointestinal diseases (EGIDs). Activation of the OX40 pathway aggravates allergic diseases, such as asthma, but it is not clear whether OX40 is expressed in eosinophils to …

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A Distributed Deadline Propagation Approach to Reduce Long-Tail in Datacenters

Rui qiang Ren, Jiuyue Ma, Xiufeng Sui, Bao Yungang