Ho Jin Shin

Effects of Medial and Lateral Foot Wedge Placement on Lower Limb Biomechanics and Muscle Activation During the Split Squat: A Randomized Crossover Trial

Seung Hun Lee, Young Min Lee, Ho Jin Shin, Jung Won Kwon

Background and Objectives: Foot wedges are widely used to modulate ankle alignment in clinical and athletic settings, yet the effects of mediolateral wedge placement on multi-planar lower limb biomechanics during functional unilateral exercises remain poorly characterized. This study aimed to quantify the …

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frontMIND: Phase 3 study of tafasitamab (Tafa) plus lenalidomide (Len) and R-CHOP for patients (pts) with newly diagnosed diffuse large B-cell lymphoma (DLBCL).

Georg Lenz, Marek Trněný, John M. Burke, Grzegorz S. Nowakowski et autres

LBA7000 Background: ~40% of DLBCL pts are not cured with first-line (1L) R-CHOP, underscoring a significant unmet need for more effective 1L regimens. Tafa (anti-CD19 mAb) + Len-R-CHOP in the phase 1b First-MIND study demonstrated safety and efficacy in pts with newly …

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First-line odronextamab (Odro) plus chemotherapy (CHOP) in diffuse large B-cell lymphoma (DLBCL): OLYMPIA-3 Part 1B results.

Matthew Matasar, Thomas Jandl, Rita Assi, Philip Kuriakose et autres

7009 Background: Approximately 25% of patients (pts) treated with rituximab + CHOP do not have a complete response (CR), and those with refractory/relapsed disease or high-risk features have poor outcomes. To address this unmet need, bispecific antibody combinations are being evaluated. In …

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Impact of VT-EBV-N on disease-free survival as post-remission therapy in EBV-positive extranodal NK/T-cell lymphoma: A randomized, double-blind, placebo-controlled phase 2 study.

Youngwoo Jeon, Young Rok, Won-Sik Lee, Sung-Yong Kim et autres

7005 Background: Extranodal NK/T-cell lymphoma (ENKL) is an aggressive EBV-associated malignancy. Although complete remission (CR) can be achieved with intensive therapy, patients with high-risk features remain at substantial risk of relapse, and no standard post-remission therapy exists. VT-EBV-N is an autologous EBV-specific …

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Correlation Between Age, Physical Characteristics, Gait Speed, Balance Ability, and Spatiotemporal Gait Parameters

Ho Jin Shin, Shin Young Kim

Purpose: Walking is an essential activity of daily life and serves as a key indicator reflecting an individual's physical function and health status.This study analyzed the correlation between age, physical characteristics, gait speed, balance ability, and spatiotemporal gait parameters in healthy adults.In …

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Correction: Evidence‑based Korean guidelines for the clinical management of multiple myeloma: addressing 12 key clinical questions

Sung‐Hoon Jung, Young‐Il Koh, Min Kyoung Kim, Jin Seok Kim et autres

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Comparison of chemoport and Hickman central venous catheters in patients with hematological cancer

Changsung Han, Gwon-Min Kim, Ho Jin Shin, Do Young Kim et autres

Background: Most patients with advanced malignancies require chemotherapy as a fundamental component of treatment. A durable venous access device is essential to facilitate the repeated administration of chemotherapeutic agents. However, there is relatively limited research on the selection of optimal access methods. …

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Evidence-based Korean guidelines for the clinical management of multiple myeloma: addressing 12 key clinical questions

Sung‐Hoon Jung, Young‐Il Koh, Min Kyoung Kim, Jin Seok Kim et autres

Multiple myeloma (MM), a hematological malignancy, is characterized by malignant plasma cell proliferation in the bone marrow. Recent treatment advances have significantly improved patient outcomes associated with MM. In this study, we aimed to develop comprehensive, evidence-based guidelines for the diagnosis, prognosis, …

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Reduced-intensity chemotherapy with tyrosine kinase inhibitor followed by allogeneic transplantation is effective in patients with Philadelphia chromosome-positive acute lymphoblastic leukemia

Jung Min Lee, Do Young Kim, Hee Jeong Cho, Joon Ho Moon et autres

BACKGROUND/AIMS: To determine the effectiveness of tyrosine kinase inhibitor (TKI) plus reduced-intensity therapy in adult patients with newly diagnosed Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph-positive ALL), this retrospective study compared treatment outcomes and induction mortality according to backbone regimen intensity. METHODS: The …

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Combination of rituximab and methotrexate followed by rituximab and cytarabine in elderly patients with primary central nervous system lymphoma

Jun Ho Yi, Seok Jin Kim, Deok‐Hwan Yang, Young Rok et autres

The optimal treatment strategy for newly diagnosed primary central nervous system lymphoma (PCNSL) has yet to be established, especially in the elderly. In the current study, we conducted a phase II study to evaluate the efficacy and safety of rituximab plus high-dose …

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Clinical significance of bone marrow involvement by immunoglobulin gene rearrangement in de novo diffuse large B-cell lymphoma: a multicenter retrospective study

Yu Ri Kim, Ho Jin Shin, Ho‐Young Yhim, Deok‐Hwan Yang et autres

Background Bone marrow (BM) involvement is an indicator of a poor prognosis in diffuse large B-cell lymphoma (DLBCL); however, few studies have evaluated the role of immunoglobulin gene rearrangement (IgR) in detecting BM involvement. Methods We evaluated the clinical characteristics and treatment …

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The Immediate Effect of Static and Dynamic Stretching on Flexibility of Hamstring, Dynamic Balance Ability, Function of Lower Extremity: Randomized Controlled Trial

Ho Jin Shin, Eunji Kim, Shin Young Kim

Purpose: This study examined the acute effects of static and dynamic stretching on the flexibility of the hamstring, dynamic balance ability, and function of the lower extremities in healthy adults.Methods: Thirty participants were assigned randomly to three groups: static stretching group (SSG), …

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