Accès ouvert
2020
article
OpenAlex
Gustavo Rocha Garcia, José M. C. Ribeiro, Sandra Regina Maruyama, Luiz Gustavo Gardinassi et autres
The cattle tick, Rhipicephalus microplus, is a monoxenous tick that co-evolved with indicine cattle on the Indian subcontinent. It causes massive damage to livestock worldwide. Cattle breeds present heritable, contrasting phenotypes of tick loads, taurine breeds carrying higher loads of the parasite …
br, us
(code pays fourni par la source)
Accès ouvert
2018
book-chapter
OpenAlex
Isabel Kinney Ferreira de Miranda Santos, Gustavo Rocha Garcia, Priscila Silva Oliveira, Cecı́lia José Verı́ssimo et autres
Rhipicephalus microplus, the cattle tick, causes enormous losses for producers of beef, dairy and leather. Currently acaricides are the only method of treatment available to producers, but they are losing their efficacy due to alarming rates of resistance in tick populations, with …
br, Afrique du Sud
(code pays fourni par la source)
Accès ouvert
2017
article
OpenAlex
Ala E. Tabor, Abid Ali, Gauhar Rehman, Gustavo Rocha Garcia et autres
Ticks are able to transmit tick-borne infectious agents to vertebrate hosts which cause major constraints to public and livestock health. The costs associated with mortality, relapse, treatments and decreased production yields are economically significant. Ticks adapted to a hematophagous existence after the …
au, br, pk, gb
(code pays fourni par la source)
Accès ouvert
2017
article
OpenAlex
Luiz Gustavo Gardinassi, Thiago S. DeSouza-Vieira, Naila O. da Silva, Gustavo Rocha Garcia et autres
BACKGROUND: Infections with parasites of the Leishmania donovani complex result in clinical outcomes that range from asymptomatic infection to severe and fatal visceral leishmaniasis (VL). Neutrophils are major players of the immune response against Leishmania, but their contribution to distinct states of …
br
(code pays fourni par la source)
Accès ouvert
2017
article
OpenAlex
Sandra Regina Maruyama, Gustavo Rocha Garcia, Felipe R. Teixeira, Lucinda Giampietro Brandão et autres
BACKGROUND: Ticks cause massive damage to livestock and vaccines are one sustainable substitute for the acaricides currently heavily used to control infestations. To guide antigen discovery for a vaccine that targets the gamut of parasitic strategies mediated by tick saliva and enables …
br, us, cz
(code pays fourni par la source)
Accès ouvert
2017
article
OpenAlex
Gustavo Rocha Garcia, Sandra Regina Maruyama, Kristina T. Nelson, José M. C. Ribeiro et autres
BACKGROUND: Males of the cattle tick Rhipicephalus microplus produce salivary immunoglobulin-binding proteins and allotypic variations in IgG are associated with tick loads in bovines. These findings indicate that antibody responses may be essential to control tick infestations. Infestation loads with cattle ticks …
br, us, nl
(code pays fourni par la source)
Accès ouvert
2017
article
OpenAlex
Alessandra Mara Franzin, Sandra Regina Maruyama, Gustavo Rocha Garcia, Rosane Oliveira et autres
BACKGROUND: Ticks attach to and penetrate their hosts' skin and inactivate multiple components of host responses in order to acquire a blood meal. Infestation loads with the cattle tick, Rhipicephalus microplus, are heritable: some breeds carry high loads of reproductively successful ticks, …
br, us, Kenya
(code pays fourni par la source)
Accès ouvert
2016
article
OpenAlex
Luiz Gustavo Gardinassi, Gustavo Rocha Garcia, Carlos Henrique Nery Costa, Vladimir Costa Silva et autres
Visceral leishmaniasis (VL) can be lethal if untreated; however, the majority of human infections with the etiological agents are asymptomatic. Using Illumina Bead Chip microarray technology, we investigated the patterns of gene expression in blood of active VL patients, asymptomatic infected individuals, …
br
(code pays fourni par la source)
Accès ouvert
2016
article
OpenAlex
Lizandra Guidi Magalhães, Thaís C. Lima, Renato Graciano de Paula, Enyara Rezende Morais et autres
Two-dimensional gel electrophoresisa b s t r a c t Schistosomiasis, a chronic disease that affects million people worldwide, is caused by trematode flukes of the genus Schistosoma.The lack of an anti-schistosomiasis vaccine and massive monotherapy with praziquantel reinforces the need for …
br
(code pays fourni par la source)
Accès ouvert
2014
article
OpenAlex
Luiz Gustavo Gardinassi, Viktoria Dotz, Agnes L. Hipgrave Ederveen, Roque Pacheco de Almeida et autres
UNLABELLED: Visceral leishmaniasis (VL) has a high fatality rate if not treated; nevertheless, the majority of human infections with the causative agent, Leishmania infantum chagasi, are asymptomatic. Although VL patients often present with increased levels of serum immunoglobulins, the contribution of antibodies …
br, nl
(code pays fourni par la source)
Accès ouvert
2014
article
OpenAlex
Gustavo Rocha Garcia, Luiz Gustavo Gardinassi, José M. C. Ribeiro, Elen Anatriello et autres
BACKGROUND: Tick salivary constituents antagonize inflammatory, immune and hemostatic host responses, favoring tick blood feeding and the establishment of tick-borne pathogens in hosts during hematophagy. Amblyomma triste, A. cajennense and A. parvum ticks are very important in veterinary and human health because …
br, us
(code pays fourni par la source)
Accès ouvert
2014
article
OpenAlex
Sandra Regina Maruyama, Luíza Antunes de Castro-Jorge, José M. C. Ribeiro, Luiz Gustavo Gardinassi et autres
Transcripts similar to those that encode the nonstructural (NS) proteins NS3 and NS5 from flaviviruses were found in a salivary gland (SG) complementary DNA (cDNA) library from the cattle tick Rhipicephalus microplus. Tick extracts were cultured with cells to enable the isolation …
br, us
(code pays fourni par la source)