Huili Li

Crystal structures and snapshots along Tpt1-catalyzed phosphate transfer from nucleic acid to NAD+

Chulei Cao, Jie Yang, Weizhen Zhang, Jiaqin Chen et autres

Tpt1/TRPT1/KptA family proteins are evolutionarily conserved in all three domains of life. In fungi and plants, Tpt1 transfers 2’-PO42- from tRNA splice junction to NAD+, which is the final step of tRNA maturation and is critical for the function of tRNA. In …

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Genome-wide identification of abnormal alternative splicing and RBP regulators in intestinal failure-associated liver disease

Tao Zhang, Xinyi Wang, Huili Li

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From Terrestrial Plants to Marine Macroalgae: A Comprehensive Review of Cell Wall Component-Properties, Extraction, Modification, and Application of Algal Cellulose

Rui Li, Ronglian Xing, Huili Li, Junli Ren et autres

Biomass cellulose is traditionally derived from terrestrial lignocellulose, but marine macroalgae are also valuable and indispensable sources of cellulose. Herein, a comprehensive comparison of algal cellulose and terrestrial plant cellulose, the properties of cellulose derived from different macroalgae, and the extraction and …

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Predicting flavonoid physicochemical properties using topological indices and regression modeling

Huili Li, Shamaila Yousaf, Komal Shahzadi, Sobhy Mostafa Ibrahim et autres

Flavonoids, a diverse class of polyphenolic phytochemicals, exhibit multifaceted biological activities critical to human health. This study leverages degree-based topological indices (TIs) to predict six physicochemical properties of sixty flavonoids using linear, quadratic, and logarithmic regression models. Statistical validation via correlation coefficients …

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Robust face mask detection in complex scenarios using YOLOv8 and context-aware convolutions

Yingjie Wei, Huili Li, Yuanfei He, Li Li et autres

Aiming to address the challenges of reduced detection accuracy in face mask applications due to mutual occlusion, lighting variations, and detection distance, this paper proposes a face mask detection algorithm tailored for complex environments. First, we construct a comprehensive face mask dataset. …

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Structural and functional studies of the main replication protein NS1 of human parvovirus B19

Yixi Zhang, Boming Fan, Yanqing Gao, Jie Yang et autres

Parvovirus B19 (B19V) is a ubiquitous virus that can infect the majority of human population and cause erythema infectiosum, acute arthropathy, and many other diseases. The main replication protein NS1 plays a critical role in cell cycle arrest, transactivation of viral and …

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Algicidal activity and mechanism of novel Bacillamide a derivative against red tide algae Skeletonema costatum and Prorocentrum minimum

Huili Li, Xiaoxue Li, Yi Liu, Ronglian Xing et autres

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Topological analysis and predictive modeling of amino acid structures with implications for bioinformatics and structural biology

Huili Li, Anisa Naeem, Shamaila Yousaf, Adnan Aslam et autres

Amino acids, as the fundamental constituents of proteins and enzymes, play a vital role in various biological processes. Amino acids such as histidine, cysteine, and methionine are known to coordinate with metal ions in proteins and enzymes, playing critical roles in their …

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Design, Synthesis, and Evaluation of Novel Thiazole-Containing Algicides Inspired by Bacillamide A

Xiaoxue Li, Huili Li, Lei Shi, Yuguo Du et autres

The pursuit of highly effective, low-toxicity, and eco-friendly algicides for controlling and eradicating harmful algal blooms (HABs) is of paramount importance. The natural allelochemical bacillamide A has displayed impressive algicidal activity against harmful algae with favorable safety profiles. However, the poor synthetic …

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Triglyceride index as a predictor of mortality after cardiac surgery

Huili Li, Xiao Fei, Haiqiang Ren, Fei Xu et autres

Background: The triglyceride-glucose (TyG) index, a marker for insulin resistance, has been linked to adverse cardiac outcomes. Its role in predicting mortality following cardiac surgery remains unclear. Methods: This study analyzed 1,810 cardiac surgery patients from the Medical Information Mart for Intensive …

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Understanding the anatomy of pelvic fascia: implications for regional anesthesia

Peiqi Shao, Zhangran Ai, Huili Li, Ruijuan Guo et autres

The fascia, a continuous structure around the whole body across various anatomical locations, remains underexplored in regional anesthesia. The pelvic fascia is a particularly controversial and complicated anatomical structure. It holds significant relevance not only for surgeons but also in the realms …

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Strontium zinc silicate simultaneously alleviates osteoporosis and sarcopenia in tail-suspended rats via Piezo1-mediated Ca2+ signaling

Lingwei Huang, Yiren Jiao, Hangbin Xia, Huili Li et autres

Long-term physical inactivity probably leads to a co-existence of osteoporosis and sarcopenia which result in a high risk of falls, fractures, disability and even mortality. However, universally applicable and feasible approaches are lacking in the concurrent treatment of osteoporosis and sarcopenia. In …

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