Penghui Li

Differential hypothalamic expression of Musashi protein 2 in Mongolian sheep with single and double ovulation

Jiaxin Fan, Penghui Li, Bingkun Teng, Haodong Liu et autres

Introduction Musashi-2 (MSI2) is an RNA-binding protein involved in the regulation of mammalian reproduction. However, its expression characteristics and role in hypothalamic reproductive regulation in Mongolian sheep remain unclear. We investigated the differential expression of MSI2 in key hypothalamic nuclei of Mongolian …

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Differential expression of Musashi 2 in single and double corpus luteum of hybrid Mongolian sheep

Hao Qinqin, Penghui Li, Hefeng Zhu, Cao Guifang et autres

This study aimed to investigate the differential expression of Musashi 2 (MSI2) in the single and double corpus lutea of Mongolian sheep (Xing’an black sheep) and its role in multiparity. Results showed two synonymous SNPs identified in the exons of MSI2 . …

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Study on regression model of shear strength of root-soil composite under freeze-thaw action

Penghui Li, Hao Li, Honglan Ji, Hongze Song

Currently, the deterioration mechanism of root containing soil performance under freeze-thaw cycles remains poorly understood, and existing prediction models seldom systematically account for the influence of freeze-thaw cycles. In this study, the reed root-sandy silt in the Inner Mongolia section of the …

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MSI2 expression in single vs. double dominant follicles and its role in Mongolian sheep fecundity

Hao Qinqin, Penghui Li, Zhou Xin, He S. Yang et autres

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MSI2 in the dentate gyrus and ovary regulates the reproductive endocrine homeostasis of female mice

Haodong Liu, Penghui Li, Yang He, Mingyang Yu et autres

Musashi2 (MSI2) plays a crucial role in neural stem cells and reproductive regulation, yet its mechanism in integrating the neuro-endocrine system remains poorly understood. This study investigates how MSI2 influences ovarian function by using conditional knockout mice for Msi2 in the brain …

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Paraventricular nucleus–locus coeruleus VGlut2 neural circuit regulates energy metabolism in mice

Haodong Liu, Penghui Li, Mingyang Yu, Xin Zhang et autres

Abstract The role of the central nervous system in energy homoeostasis remains unclear. This study examined the role of VGlut2-expressing neurons in the paraventricular nucleus of the hypothalamus (PVH VGlut2 ) and their downstream circuits in the regulation of energy homoeostasis. Long-term …

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Systemic immune-inflammation index is associated with cardiac complications following acute ischemic stroke: A retrospective single-center study

Xiaodi Hao, Mingfang Zhu, Zhengyu Sun, Penghui Li et autres

BACKGROUND: Stroke-induced heart syndrome is a feared complication of ischemic stroke, that is commonly encountered and has a strong association with unfavorable prognosis. More research is needed to explore underlying mechanisms and inform clinical decision making. This study aims to explore the …

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Identification and Characterization of Prognostic Macrophage Subpopulations for Human Esophageal Carcinoma

Penghui Li, Xiaohui Gao, Di Huang, Xinyu Gu

AIMS: The aim of the present study was to investigate the relationship between the cellular ecosystem and the progression of esophageal carcinoma (ESCA) based on the evolution of macrophages and to analyze the potential of using macrophages as a new therapeutic approach …

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Glutamatergic melanocortin‐4 receptor neurons regulate body weight

Haodong Liu, Xiaojing Li, Penghui Li, Rihan Hai et autres

Abstract The locus coeruleus (LC), enriched in vesicular glutamate transporter 2 (VGlut2) neurons, is a potential homeostasis‐regulating hub. However, the identity of melanocortin‐4 receptor (MC4R) neurons in the paraventricular nucleus (PVN) of the hypothalamus, PVN VGlut2::MC4R and LC VGlut2::MC4R regulation of body …

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Aerosol deposition in the pulmonary acinar region: Influence of wall motion and interparticle collisions

Penghui Li, Weiqi Guo, Jinbo Fan, Chen Su et autres

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Amylin regulates testosterone levels via steroidogenesis-related enzymes in the central nervous system of male mice

Yujie Chen, Qiang Li, Xiaojing Li, Haodong Liu et autres

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Inhibitory effect of central ghrelin on steroid synthesis affecting reproductive health in female mice

Deng Pan, Kun Wang, Guifang Cao, Kuikui Fan et autres

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