Hao Yu Wu

Association study of 11 food groups with cardiovascular disease: a cross-sectional study based on Shandong Province, China, 2015–2016

Jinxia Hu, Huali Meng, Haojia Yu, Tingting Zhang et autres

Background: Despite the fact that comprehensive research has demonstrated that dietary behavior constitutes one of the primary risk factors for cardiovascular disease (CVD), earlier studies have exclusively concentrated on individual foods or nutrients. Therefore, to provide more effective guidance to residents in …

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Bidirectional microbial regulation by tyrosine metabolism enhances palmatine-mediated colitis protection

Daming Sun, Yunzhu Xiao, Dandan He, Hao Yu Wu et autres

Gut microbiota dysbiosis and intestinal immune dysfunction contribute to the disease pathogenesis of ulcerative colitis (UC), therapeutic strategies aim to reshape microbial balance and reduce inflammation. It is unclear that how this bidirectional regulation between microbe-immune system is achieved and what is …

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Cardamonin Commands the Colonic Metabolite Columbianetin Acetate to Compete Against LPS in Binding HMGB1 in the Kidney, Preventing Lipopolysaccharide‐Induced Renal Tubular Pyroptosis

Zihui Zhou, Xuechun Sun, Jian Min Zhou, Huali Meng et autres

ABSTRACT Sepsis‐associated acute kidney injury (SA‐AKI) results in high mortality due to the lack of effective interventions. The current study reports the protective effect of cardamonin (CAD), a member of the chalcone family, against SA‐AKI using a lipopolysaccharide (LPS)‐stimulated mouse model. CAD …

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Krill Oil Reverses White Adipose Tissue Dysfunction by Inhibiting Macrophage M1 Polarization in Mice With Type 2 Diabetes

Dongyan Song, Xiaoli Huang, Zheng Yan, Lei Sun et autres

White adipose tissue (WAT) dysfunction is a crucial contributor to insulin resistance (IR), which is the key cause for type 2 diabetes mellitus (T2DM). Macrophage infiltration and M1 polarization induce WAT dysfunction. Krill oil (KO) possesses anti-inflammation activity, but its effect on …

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Dotnet Electrode as a Novel Approach to Explore Epilepsy: Technical Note with Illustrative Cases

Hua Zhang, Huanfa Li, Yong Liu, Qiang Meng et autres

BACKGROUND: Intracranial electroencephalography (iEEG) is utilized to localize the seizure-onset zone (SOZ). However, sampling sites of electrodes for iEEG are limited to partial brain coverage because of the unacceptable trauma of implantation. The limitation may lead to missing the SOZ because of …

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Three-dimensional left atrial strain analysis in patients with atrial fibrillation for stroke risk evaluation: A comparison between patients with and without stroke history

Han Yu, Hujin Xie, Zidun Wang, Hao Yu Wu et autres

Patients with atrial fibrillation (AF) are at risk for cardioembolic stroke. The recent studies suggest that reduced two-dimensional left atrial (LA) deformation, such as longitudinal strain, may be a potential indicator of stroke risk. We aim to evaluate three-dimensional (3-D) LA global …

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Elderly stroke burden: a comprehensive global study over three decades

Ruoyu Gou, Changjun Luo, Xudong Liang, Shuitao Qin et autres

Background: Stroke is a serious disease that negatively affects the quality of life of patients and has become a global public health problem. This study used data from the 2021 Global Burden of Disease (GBD) study to assess the burden of stroke …

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Interventional Therapy for a Child With Tracheal Lobular Capillary Hemangioma: A Case Report and Literature Review

Haoran Jing, Yuhuan Liu, Kewei Ma, Hao Yu Wu et autres

The authors declare no conflicts of interest. The data that support the findings of this study are available from the corresponding author upon reasonable request.

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Association between weight-adjusted-waist index and anxiety among adults in the National Health and Nutrition Examination Survey (NHANES), 2007–2012

Xiao Min Liang, Kai Chen, Siyuan Ding, Hao Yu Wu et autres

Background and aims: Anxiety is a pervasive mental health concern and has evolved into a multifaceted and pressing global health concern. Despite this, the connection between the weight-adjusted waist index (WWI) and anxiety symptoms remains unexplored. Therefore, the objective of this study …

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177-OR: Hyperglycemia Threshold Associated with Adverse Pregnancy Outcomes in Gestational Diabetes Mellitus

Guiling Liang, Shuai Yan, Yaxin Wang, JINGYI LU et autres

Introduction and Objective: The optimal glucose targets in gestational diabetes mellitus (GDM) remains unknown. This study aimed to investigate the threshold of hyperglycemia associated with adverse outcomes in GDM using continuous glucose monitoring (CGM). Methods: This prospective cohort study recruited a total …

Gut microbiota from voluntary exercised mice protects the intestinal barrier by inhibiting neutrophil extracellular trap formation

Beibei Zhu, Hao Yu Wu, Zhang Han, Qi Song et autres

Ulcerative colitis is an inflammatory bowel disease characterized by impaired intestinal barrier function, dysregulated immune responses, and alterations in the gut microbiota. Excessive formation of neutrophil extracellular traps (NETs), driven by peptidyl arginine deiminase 4 (PAD4) activity, contributes to inflammation modulated by …

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Impact of multiplicative noise removal on digital volume correlation-based optical coherence elastography

Hao Yu Wu, Jiaqiu Wang, Zhengduo Zhu, Han Yu et autres

Digital volume correlation-based optical coherence elastography (DVC-based OCE) may easily suffer from multiplicative speckle noise of optical coherence tomography (OCT) imaging, which can introduce non-negligible calculation errors. In this study, Hamilton-Jacobi partial differential equations were adopted for multiplicative noise removal of OCT …

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