Jin Woong Kim

Label-Free Near-Infrared Image Cytometry for Chlorophyll Quantification and Carotenoid Prediction with Multiparametric Biophysicochemical Profiling

Seongcheol Park, Gueeda Kim, Youngho Song, Changyu Tian et autres

Microalgae offer a promising platform for carotenoid manufacturing due to their productivity, tunable selectivity, and compatibility with large-scale bioprocessing. Yet, their cellular responses exhibit highly heterogeneous and asynchronous pigment and morphological transitions under fluctuating light stress, making precise prediction and process optimization …

kr (code pays fourni par la source)

Mechanical stress-driven conformational compaction of polydeoxyribonucleotide for enhanced transdermal regenerative therapy

Saetbyeol Jeon, Jung Im Lee, Shim Ss, Chul Hwan Kim et autres

Biomacromolecular therapeutics face critical size-dependent transdermal delivery limitations that restrict their clinical effectiveness. To overcome this constraint, a conformation-altering strategy using controlled mechanical stress is reported to achieve substantial structural compaction of polydeoxyribonucleotide (PDRN) without chemical intervention. By applying mild vacuum conditions …

kr (code pays fourni par la source)

Melanocortin 1 receptor-targeted peptide-functionalized liposomes for enhanced melanocyte-preferential drug delivery and anti-melanogenic efficacy

Donghan Kim, Hwira Baek, Marta Gonçalves, Seyoung Yang et autres

results in melanin reduction and decreased tyrosinase expression. These findings indicate that MC1R-targeted liposomal delivery achieves melanocyte-preferential internalization and anti-melanogenic efficacy, suggesting translational potential in the topical management of pigmentary disorders and cosmetic depigmentation applications.

kr (code pays fourni par la source)

Transition metal chalcogenide nanowires-integrated extracellular matrix analogues for modulating redox microenvironment in tissue regeneration

Hyunhee Cho, Chaeheon Woo, Seul‐Gi Kim, Woo Jin Gil et autres

kr (code pays fourni par la source)

Cell-Penetrating Peptide-engineered Solid Lipid Nanoparticles for Enhanced Endocytotic Internalization and Transdermal Penetration

Jongryeol Yang, Seulgi Kim, Minjoo Noh, Jun Bae Lee et autres

Efficient drug delivery across biological barriers remains a fundamental challenge, particularly for rigid nanocarriers whose penetration mechanisms are poorly understood. Here we demonstrate that Laminin-332-functionalized solid lipid nanoparticles (SLN Lam ) overcome cellular barriers through receptor-mediated endocytosis and achieve substantial transdermal penetration. …

kr, nl, hk (code pays fourni par la source)

Label-free and real-time monitoring of photoaging with high spatiotemporal resolution using an nIR fluorescent nanosensor array

Youngwook Cho, Hwira Baek, Damee Koh, Changyu Tian et autres

Reactive oxygen species (ROS) bursts from photoaging cause skin damage and chronic conditions. Understanding spatiotemporal ROS dynamics is critical for developing therapies and cosmetic strategies to enhance skin health. Conventional assays and fluorescence microscopy lack the resolution for real-time ROS quantification due …

kr (code pays fourni par la source)

Mechanobiologically Engineered Mimicry of Extracellular Vesicles for Improved Systemic Biodistribution and Anti‐Inflammatory Treatment Efficacy in Rheumatoid Arthritis

Dahwun Kim, Hwira Baek, Su Yeon Lim, Min Sang Lee et autres

Abstract Liposomal membrane elasticity is a controlling parameter in designing liposome‐based drug delivery systems and significantly affects biodistribution and biofunctional effects. Although extensively investigated in tumor models, the impact of liposomal membrane elasticity on rheumatoid arthritis (RA) remains underexplored. RA presents unique …

kr (code pays fourni par la source)

0847 The addition of collagen scaffolds to human cell therapy to modify skin identity

Sam-Sun Lee, Yingchao Xue, A. Li, Elizabeth Winnicki et autres

us (code pays fourni par la source)

Metal-Oxide-Decorated Mesoporous Silica Chemiresistors for Exhaled Biomarker Detection

Minchul Sung, Min Jun Oh, Tiancheng Wang, Jaeyong Ahn et autres

High Resolution Image Download MS PowerPoint Slide A metal-oxide-decorated mesoporous silica (MOMS) chemiresistor platform enables the selective detection of disease-specific volatile organic compounds (VOCs) in exhaled breath. Functionalization of these mesoporous structures with metals and metal oxides facilitates the detection of a …

kr, us (code pays fourni par la source)

Microalgae-Derived Microparticles Improve Immunomodulation via Combined Glycolysis and MAPK Activation

Hwira Baek, Seul‐Gi Kim, Young-Seok Kim, Junoh Kim et autres

Natural polysaccharides possess potent immunostimulatory properties, but their poor solubility impedes efficiency of cellular delivery. This study focuses on extraction of microparticles (MPs) from Euglena gracilis, a microalgae species characterized by abundant intracellular β-1,3-glucan and flexible cell membrane. We introduce an E. …

kr (code pays fourni par la source)

Charge‐Directed Nanocellulose Assembly for Interfacial Phase‐Transfer Catalysis

Jaewon Shin, Bokgi Seo, Kyoung-Ho Choi, DaAe Park et autres

Abstract Liquid–liquid interfaces present unique opportunities for sustainable biphasic catalysis, yet concurrent amplification of molecular transport and reactivity at these boundaries remains challenging. Here it is demonstrated that high‐aspect‐ratio cationic nanocellulose (HNC+) spontaneously self‐assembles into mechanically robust nanomesh architectures at oil‐water interfaces …

kr, us (code pays fourni par la source)

Metal‐Phenolic Networks Enable Biomimetic Antioxidant Interfaces Through Nanocellulose Engineering

Bokgi Seo, Seul‐Gi Kim, Dongyoung Jeon, Taejoon Kim et autres

Metal-phenolic networks (MPNs) integrated with functionalized cellulose nanofibers present a promising platform for stabilizing oxidation-sensitive compounds. Here, a novel antioxidant pickering emulsion system utilizing MPN-decorated carboxyl-functionalized pulp cellulose nanofibers (MPN-PCNF) is demonstrated. The system exhibits exceptional interfacial stability through synergistic effects of …

kr (code pays fourni par la source)