Lei Shi

Larval Root Feeding by Megistophylla grandicornis (Coleoptera: Scarabaeidae): An Emerging Threat to Eucalyptus Plantations

Xiaohong Huang, Tao-Yuan Du, Lei Shi

Eucalyptus plantations have suffered severe damage from scarab grubs in recent years. To investigate the actual scarab species that damage Eucalyptus trees, continuous closed-net monitoring and monthly soil-digging surveys were conducted in Eucalyptus plantations in Lancang County, China, from 2024 to 2025. …

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Comprehensive analysis of risk factors associated with carotid plaque in patients with type 2 diabetes mellitus

Lei Shi, Na Li

BACKGROUND Carotid atherosclerosis is a common complication in patients with type 2 diabetes mellitus (T2DM) and is closely associated with an increased risk of cardiovascular events. AIM To identify the key demographic, clinical, and biochemical factors associated with carotid plaque formation in …

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N-terminal domain of CTRP9 promotes cardiac fibroblast activation in myocardial infarction via Rap1/Mek/Erk pathway

Yanzhen Tan, Haipeng Li, Guojie Cao, Jialin Xin et autres

BACKGROUND: In developed nations, myocardial infarction (MI) is one of the main causes of morbidity and mortality, resulting in a significant economic burden and becoming a global public health problem. C1q/tumor necrosis factor-related protein 9 (CTRP9) is a secreted protein comprising a …

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Corrigendum to “Melatonin inhibits angiotensin II–induced atrial fibrillation through preventing degradation of Ang II Type I Receptor–Associated Protein (ATRAP)” [Biochem. Pharmacol. 202 (2022) 115146]

Xin Xie, Tingting Shen, Hai-Lian Bi, Zhuo-Lin Su et autres

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CTRP3 alleviates mitochondrial dysfunction and oxidative stress injury in pathological cardiac hypertrophy by activating UPRmt via the SIRT1/ATF5 axis

Lei Shi, Yanzhen Tan, Wenying Zheng, Guojie Cao et autres

Pathological cardiac hypertrophy is an independent risk factor for heart failure. Disruption of mitochondrial protein homeostasis plays a key role in pathological cardiac hypertrophy; however, the mechanism of maintaining mitochondrial homeostasis in pathological cardiac hypertrophy remains unclear. In this study, we investigated …

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Low‐dose exercise protects the heart against established myocardial infarction via IGF‐1‐upregulated CTRP9 in male mice

Yanzhen Tan, Feng Pan, Lele Feng, Lei Shi et autres

Regular exercise is recommended as an important component of therapy for cardiovascular diseases in clinical practice. However, there are still major challenges in prescribing an optimized exercise regimen to individual patients with established cardiac disease. Here, we tested the effects of different …

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Epicardial adipose tissue, metabolic disorders, and cardiovascular diseases: recent advances classified by research methodologies

Yujie Song, Yanzhen Tan, Meng Deng, Wenju Shan et autres

Epicardial adipose tissue (EAT) is located between the myocardium and visceral pericardium. The unique anatomy and physiology of the EAT determines its great potential in locally influencing adjacent tissues such as the myocardium and coronary arteries. Classified by research methodologies, this study …

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Forkhead box O6 (FoxO6) promotes cardiac pathological remodeling and dysfunction by activating Kif15–TGF‐β1 under aggravated afterload

Bing Zhang, Lei Shi, Yanzhen Tan, Yenong Zhou et autres

Pathological cardiac hypertrophy exhibits complex and abnormal gene expression patterns and progresses to heart failure. Forkhead box protein O6 (FoxO6) is a key transcription factor involved in many biological processes. This study aimed to explore the role of FoxO6 in cardiac hypertrophy. …

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The anatomic study and surgical technique for canal decompression with “pedicle-plasty” strategy in lumbar burst fractures with pedicle rupture

Zuo-Zhong Liu, Lei Shi, Zhengjian Yan, Jianhua Ran et autres

In the treatment of lumbar burst fractures with nerve injury, fusion is often required to rebuild spinal stability, but it can lead to the loss of motor units and increase the occurrence of adjacent segment diseases. Thus, a novel approach of lumbar …

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GLUT4 mediates the protective function of gastrodin against pressure overload-induced cardiac hypertrophy

Miao Zhang, Yanzhen Tan, Yujie Song, Min Zhu et autres

Gastrodia elata exhibits extensive pharmacological activity; its extract gastrodin (GAS) has been used clinically to treat cardiovascular diseases. In the present study, we examined the effect of GAS in a mice model of pathological cardiac hypertrophy, which was induced using transverse aortic …

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Do acute and chronic physical activity interventions affect the cognitive function of preschool children? A meta-analysis

Huiqi Song, Jingjing Wang, Borui Zhang, Lei Shi et autres

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Efficacy of tolvaptan in postoperative volume therapy for acute Stanford type A aortic dissection

Wenjun Wang, Feng Gao, Xuezhi He, Yang Gao et autres

BACKGROUND: Despite the increasing application of tolvaptan in cardiac surgery, there is no information on the use of tolvaptan in Stanford patients with type A aortic dissection. This study aimed to evaluate the postoperative clinical effects of tolvaptan in patients with type …

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