Ming Zhang

Dietary vitamin B6 intake and gallstone prevalence in US adults

Chengchen Liu, Nan Gao, Xun Yan, Ming Zhang et autres

Although mechanistic data implicate vitamin B6 in the regulation of cholesterol metabolism and inflammatory pathways, the epidemiological nexus between dietary vitamin B6 consumption and gallstone susceptibility remains largely uncharted in population-based cohorts. Leveraging cross-sectional data from the National Health and Nutrition Examination …

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Predictive Modelling of 3‐Month Glycemic Target Achievement in Type 2 Diabetes Mellitus Using Artificial Intelligence and Continuous Glucose Monitoring: A Retrospective Cohort Study

Qinyan Huang, Jing Kang, Rui Wang, Ming Zhang et autres

AIMS: To develop and validate a machine learning model incorporating continuous glucose monitoring (CGM) metrics to predict 3-month glycemic target achievement in type 2 diabetes mellitus (T2DM) after short-term intensive insulin pump therapy followed by physician-selected maintenance treatment, and to build a …

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Prognostic value of the triglyceride–glucose index in patients with premature acute coronary syndrome

Yifan Sun, Jibin Chen, Nianzu Wei, Ming Zhang et autres

BACKGROUND: The triglyceride-glucose (TyG) index has been proposed as an accessible indicator of insulin resistance and cardiometabolic risk. However, its prognostic relevance in patients with premature acute coronary syndrome has not been well defined. We therefore examined baseline clinical features and long-term …

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Neddylation: from regulatory mechanisms to clinical implications in cancer

Ming Zhang, Qiu Peng, Yunxiang Feng, Wei Yao et autres

• The review highlights neddylation as a crucial post-translational modification, detailing its regulation of protein function and subsequent alterations in cellular activities. • Providing in-depth analysis of cullins family-related substrates and their biological functions. • Contextualizing within cancer hallmarks, the review comprehensively …

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B lymphocytes and hyperglycemia synergistically exacerbate coronary in-stent restenosis

Siyao Ni, Sheng Liu, Chenyang Wang, Kexin Yang et autres

Background: Lymphocytes are tightly associated with coronary artery disease (CAD). However, there is a lack of clinical evidence that lymphocyte subsets are associated with in-stent restenosis (ISR). The aim of this clinical research was to elucidate the association between these. Methods: T …

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GLI1 amplification and fusion in MDM2 -amplified low-grade osteosarcoma

Lan Li, Ming Zhang, Xiaoqi Sun, Yuzi Zhang et autres

Aims Glioma-associated oncogene homologue 1 ( GLI1 ) was recently shown to be coamplified with mouse double minute 2 ( MDM2 ), cyclin-dependent kinase 4 ( CDK4 ) and some other adjacent genes in a significant subset of GLI1 -altered mesenchymal tumours …

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Clinical Diagnostic and Prognostic Value of Residual Language Learning Ability in Patients with Disorders of Consciousness

Yan Chen, Xiangyue Xiao, Zhicai Dong, Junhua Ding et autres

Recent research suggests that the detection of preserved cognitive function can assist in the diagnosis and prognosis of patients with disorders of consciousness (DoC). This study investigates EEG signals as indicators of neural activity associated with the processing of transitional probabilities during …

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Aberrant bcl6 protein expression in patients with EMZL following recurrence or progression: case report of two cases

Ming Zhang, Jianli Qu, Weiwei Guo, Yi Liu et autres

Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (EMZL) is an indolent B-cell lymphoma that can involve various anatomic sites. EMZL is derived from post-germinal center marginal zone B cells and typically lacks bcl-6 expression. Herein, we report two post-treatment cases of …

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Chronic intermittent hypoxia exacerbates isoproterenol-induced cardiac hypertrophy and apoptosis

Yujie Zhang, Ming Zhang, Hongfeng Jiang, Fang Fang

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Aberrant bcl6 protein expression in patients with EMZL following recurrence or progression: case report of two cases

Ming Zhang, Jianli Qu, Weiwei Guo, Yi Liu et autres

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Incidence and risk factors associated with atrioventricular block in the general population: the atherosclerosis risk in communities study and Cardiovascular Health Study

Jingwei Zhang, Jia‐Bao Liu, Min Ye, Ming Zhang et autres

OBJECTIVES: To identify risk factors correlated with atrioventricular block (AVB) in the general population. METHODS: Participants in the Atherosclerosis Risk in Communities study (ARIC) and the Cardiovascular Health study (CHS) were enrolled. The presence of AVB was confirmed at an electrocardiogram (ECG) …

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Mitochondria: a new intervention target for tumor invasion and metastasis

Quanling Zhou, Tingping Cao, Fujun Li, Ming Zhang et autres

Mitochondria, responsible for cellular energy synthesis and signal transduction, intricately regulate diverse metabolic processes, mediating fundamental biological phenomena such as cell growth, aging, and apoptosis. Tumor invasion and metastasis, key characteristics of malignancies, significantly impact patient prognosis. Tumor cells frequently exhibit metabolic …

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