Bin Tian

RALP1 is essential for schizont maturation and erythrocyte invasion in Plasmodium falciparum

Jing Yun Wu, Zuping Zhang, Jiayao Pang, Wenyu Yang et autres

BACKGROUND: Plasmodium falciparum merozoite invasion of erythrocytes is an essential step in the asexual blood-stage cycle and a major target for antimalarial intervention. Rhoptry neck proteins play key roles in the formation and function of the tight junction, yet many remain poorly …

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Genetic Basis of UV Bullseye Size Variations in Turnip Rape ( Brassica rapa subsp. oleifera )

Zhi‐Li Zhou, Yu Zhang, Li‐Ling Jiang, Ang Li et autres

Floral ultraviolet (UV) patterns are visible to bee pollinators and can affect crop yields by impacting pollinator visitation. However, the mechanisms underlying the intraspecific variations of UV bullseye size remain largely unknown. We analyse the ecological consequences and genetic basis of floral …

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NS2B is indispensable for NS3/NS5 interaction of Tembusu virus in living cells

Yu He, Yi Shi, Zhen Wu, Tao Wang et autres

Tembusu virus (TMUV) causes egg-drop syndrome and neurological signs in duck, goose and chicken, posing a great threat to the waterfowl industry. In the present study, we established an in vivo protein-protein interaction system for the NS2B-3 and NS5, together with ​co-immunoprecipitation …

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DPV UL46 activates EGFR-PI3K-AKT pathway to antagonize innate immunity by interfering with cGAS-STING-TBK-IRF7 Signalsome formation

Yanming Tian, Bin Tian, Dongjie Cai, Zhen Xiao et autres

Duck plague virus (DPV), a representative species of the Alphaherpesvirinae subfamily, poses significant economic and biosecurity threats to poultry production. Although the EGFR-PI3K-AKT signaling pathway is known to regulate diverse cellular processes-including cell growth, protein synthesis and immune regulation-and plays a significant …

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The Effects of Musical Intervention on EEG Sample Entropy and Lempel-Ziv Complexity Among Drug Detoxification

Zhixun Xia, Wang Zi, Bin Tian, Jun Wang et autres

This study investigates the effects of a structured$\mathbf{6 0}$-day music intervention on brain activity in individuals undergoing drug detoxification. EEG signals were analyzed using two nonlinear measures-Sample Entropy and Lempel-Ziv (LZ) complexity-to assess neural complexity. The experimental group showed significantly higher EEG …

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Development of a reverse genetics system for West Nile virus (Kunjin type)

Zhen Wu, Tao Hu, Zhou Zhou, Yu He et autres

Kunjin virus (KUNV), a naturally attenuated strain of West Nile virus (WNV), shares similar transmission modes and hosts—primarily mosquitoes, birds, and horses. Globally, reverse genetics is the principal methodology for characterizing the molecular etiology of flaviviruses. In this study, cytomegalovirus (CMV) promoter-driven …

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Salmonella Enteritidis Outbreak Associated with Contaminated Raw Eggs in Cold-Braised Meat Assortment: Changsha, China, 2024

Dihui Ma, Bin Tian, Xu Hengbo, Wei Tang et autres

Salmonella , a significant zoonotic pathogen, remains the predominant global etiological agent of foodborne diseases and consistently ranks as one of the leading causes of foodborne disease outbreaks in China. We report a foodborne disease outbreak caused by Salmonella Enteritidis contamination of …

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High prevalence of Duck Hepatitis B virus-associated coinfection in Southwest China

Xiaoming Lin, Yajia Gou, Yi Liu, Sai Mao et autres

Currently, five types of duck hepatitis viruses have been documented, and they are all associated with liver disorders. However, the prevalence of their coinfections involving these viruses remains largely uncertain. Herein, we screened the prevalence of the five types of hepatitis viruses …

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Duck plague virus gG is secreted, nonstructural glycoprotein, not essential for viral replication and responsible for the virulence

Jie Qiu, Zihang Wang, Mingshu Wang, Anchun Cheng et autres

Duck plague virus (DPV) is a highly pathogenic member of the herpesvirus family that can induce significant morbidity and mortality, primarily manifesting as septicemia in multiple host organs. The US4 gene encodes glycoprotein gG, which is highly conserved across the alphaherpesvirus family. …

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First establishment of a Duck Model for in vivo and in vitro studies of West nile virus (Kunjin subtype)

Zhen Wu, Tao Hu, Zhou Zhou, Yu He et autres

We present a method for constructing a Kunjin virus (KUNV) infectious clone capable of stable proliferation in bacterial systems. This KUNV infectious clone successfully produces infectious viral particles within host cells. In vitro, the recombinant virus demonstrates the ability to replicate in …

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Duck plague virus UL47 gene affects the release and cell-to-cell spread of the virus and its deletion strains can provide strong protection for ducks

Yuxi Cui, Siyu Chen, Mingshu Wang, Wei Zhang et autres

Duck plague (DP) is an acute, febrile, septicemic infectious disease caused by duck plague virus (DPV). pUL47, which is encoded by the DPV UL47 gene, is a relatively abundant late tegument protein in virions, and its effects on the life cycle and …

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Fire Severity Alters Soil Microbial Diversity and Community Stability in a Subtropical Forest Ecosystem

Xuezhao Wang, Yuan Tang, Tongjian Zi, Xiaona Li et autres

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