Xinghao Wang

The gp120 Envelope Glycoprotein of HIV-1 Triggers Macropinocytosis in Primary CD4+ T Cells to Promote HIV-1 Infection

Praveen Manivannan, Cristina Santos da Costa, Yipei Tang, Xinghao Wang et autres

Macropinocytosis is a large-scale, actin-driven, fluid-phase form of endocytosis that can be exploited by HIV-1 for entry into primary CD4+ T cells. Herein, we show that HIV-1 actively induces macropinocytosis in resting and activated primary CD4+ T cells. HIV-1-induced T cell macropinocytosis …

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Chiral multi-curved shell metamaterials integrating compression-torsion and buckling mechanisms for ideal energy absorption

Chenxu Liu, Yizhi Zhang, Xinghao Wang, Gui‐Lan Yu et autres

Metamaterials with compression-torsion or buckling mechanism have demonstrated significant potential for energy absorption. However, compression-torsion metamaterials easily trigger deformation, resulting in low load-bearing capacity, and buckling ones have high peak load with fluctuations, accompanying severe localized deformations. Here, we propose chiral multi-curved …

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Modulus‐Strength Decoupled High‐Toughness Elastomer for Impact Protection

Zhongting Wang, Xinghao Wang, Yizhi Zhang, Zhiqi Wang et autres

Abstract Elastomers with decoupled modulus and strength are highly desirable for multi‐scenario applications, yet achieving this balance remains challenging due to inherent trade‐offs between flexibility and mechanical robustness. Here, based on polyurethane‐based elastomer, a strategy is reported that overcomes this limitation through …

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Chiral multi-curved shell metamaterials integrating compression-torsion and buckling mechanisms for ideal energy absorption

Zhanli Liu, Chenxu Liu, Yizhi Zhang, Xinghao Wang et autres

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Bridging biomechanics with neuropathological and neuroimaging insights for mTBI understanding through multiscale and multiphysics computational modeling

Zhibo Du, Jiarui Zhang, Xinghao Wang, Zhuo Zhuang et autres

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From Hypoxia to Buoyancy: Serotonin and Oxygen Deprivation Rewire Neutrophils

Luz P. Blanco, Jorge Romo‐Tena, Xinghao Wang, Yaima Luzardo Lightfoot et autres

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Different ethanol exposure durations affect cytochrome P450 2E1-mediated sevoflurane metabolism in rat liver

Wei Jiang, Min Zhang, Rui Cao, Xinghao Wang et autres

BACKGROUND: . This study aims to explore whether ethanol exposure could alter sevoflurane metabolism through CYP2E1 modulation, potentially explaining the increased MAC observed in alcohol users. METHODS: Eighty adult male Sprague-Dawley (SD) rats were randomly divided into two groups and received either …

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Dynamics of a Stochastic Vector-Borne Model with Plant Virus Disease Resistance and Nonlinear Incidence

Liang Zhang, Xinghao Wang, Xiao‐Bing Zhang

Symmetry in mathematical models often refers to invariance under certain transformations. In stochastic models, symmetry considerations must also account for the probabilistic nature of inter- actions and events. In this paper, a stochastic vector-borne model with plant virus disease resistance and nonlinear …

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Analyzing the contribution of helmet components to underwash effect under blast load

Jiarui Zhang, Zhibo Du, Xinghao Wang, Yue Kang et autres

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Dynamics of a Stochastic SVEIR Epidemic Model with Nonlinear Incidence Rate

Xinghao Wang, Liang Zhang, Xiao‐Bing Zhang

This paper delves into the analysis of a stochastic epidemic model known as the susceptible–vaccinated–exposed–infectious–recovered (SVEIR) model, where transmission dynamics are governed by a nonlinear function. In the theoretical analysis section, by suitable stochastic Lyapunov functions, we establish that when the threshold …

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Caught in the middle: MARCH5 mediates PD-1-induced IL-2R degradation

Xinghao Wang, Weiping Zou

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The Salmonella Typhimurium Effector SpvB Subverts Host Membrane Trafficking by Targeting Clathrin and AP-1

Yi Yuan, Xinghao Wang, Jie Jin, Zhiheng Tang et autres

Salmonella enterica, the etiological agent of gastrointestinal and systemic diseases, translocates a plethora of virulence factors through its type III secretion systems to host cells during infection. Among them, SpvB has been reported to harbor an ADP-ribosyltransferase domain in its C terminus, …

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