Shang Liu

Reprogramming CAR with Cytokine Signaling Increases the Efficacy of CAR T-cell Therapy in Solid Tumor Treatment and Confers Sustained Immune Memory

Rongchen Sun, Shang Liu, Xue Yang, Changshuai Che et autres

Chimeric antigen receptor (CAR) T-cell therapy has shown remarkable efficacy in hematologic malignancies but remains limited in solid tumors because of the immunosuppressive microenvironment, tumor heterogeneity, poor immune cell infiltration, and progressive T-cell dysfunction. Because cytokine costimulation is critical for maintaining T-cell …

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Synchronous separation of Al foil and leaching of metals in cathode materials from spent lithium-ion batteries by a deep eutectic solvent

Shang Liu, Yaoguo Huang, Linlin Chen, Xianfu Sun et autres

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Localized States Induced by Mixed-Valence Co-Doping in Amorphous ZnSe:(Mo,Ga) Films and Their Role in Optoelectronic Modulation

Shang Liu, Dongwen Gao

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From Nanopores to Macroscopic Shrinkage: A Molecular Dynamics-Driven Capillary Shrinkage Model for Concrete

yi li, Lei Zhang, Xiangqian Fan, Guanghui Wu et autres

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From Nanopores to Macroscopic Shrinkage: A Molecular Dynamics-Driven Capillary Shrinkage Model for Concrete

Yi Li, Lei Zhang, Xiangqian Fan, Guanghui Wu et autres

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Recycle of graphite and recovery of valuable metals from industrial-grade black mass of spent lithium-ion battery

Shang Liu, Linlin Chen, Yaoguo Huang, Xianfu Sun et autres

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MBE growth and characterization of strained GeSn/Ge multiple quantum well structures

Nirosh M. Eldose, Fernando M. de Oliveira, Serhii Kryvyi, Hryhorii Stanchu et autres

Abstract Germanium tin (GeSn) alloys have emerged as pivotal materials for advanced optoelectronic applications owing to their tunable bandgaps and compatibility with silicon-based technologies. In this study, high quality GeSn multiple quantum wells (MQWs) with Sn concentrations of 7.0 ± 0.5% and …

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A novel long-acting recombinant follicle-stimulating hormone with hyperglycosylation exhibits improved pharmacokinetic and bioactivity on promoting follicle growth

Rongchen Sun, Xue Yang, Shang Liu, Ting Wang et autres

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A Novel Recombinant Human FGF21 Analog with High Glycosylation Has a Prolonged Half-Life and Affects Glycemic and Body Weight Control

Pei Du, Ting Wang, Rong Wang, Shang Liu et autres

Fibroblast growth factor 21 (FGF21), a hormone-like protein, plays a crucial role in enhancing glucose and lipid metabolism, offering promising therapeutic avenues for conditions such as nonalcoholic steatohepatitis and severe hypertriglyceridemia. Despite its potential, this protein’s limited stability and brief half-life pose …

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Elucidating the size distribution of p‑Phenylenediamine-Derived quinones in atmospheric particles

Kaihui Xia, M.J. Qin, Mingming Han, Xianming Zhang et autres

Transformed from p-phenylenediamines (PPDs) antioxidant, PPD-derived quinones (PPD-Qs) have recently been recognized as emerging contaminants due to their potential negative impacts on the environment and human health. While there have been measurements of airborne PPD-Qs, the size distribution of PPD-Qs and the …

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A Multivalent mRNA Therapeutic Vaccine Exhibits Breakthroughs in Immune Tolerance and Virological Suppression of HBV by Stably Presenting the Pre-S Antigen on the Cell Membrane

Shang Liu, Jie Wang, Yunxuan Li, Muhan Wang et autres

Background/Objectives: In chronic hepatitis B infection (CHB), the hepatitis B surface antigen (HBsAg) continuously exhausts the hepatitis B surface antibody (HBsAb), which leads to the formation of immune tolerance. Accordingly, the hepatitis B virus (HBV) infection can be blocked by inhibiting the …

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Joint Optimization Strategy for Partial Offloading and Resource Allocation in Mobile Edge Computing Based on Energy Harvesting

Jingqiu Ren, Shang Liu, Guanghua Zhang

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