Li Feng

Dual-Enhanced Electrochemiluminescence Imaging on a Monolayer Film of Nanoreactors for Probing Cell–Matrix Interaction

Xuedong Huang, Li Feng, Shi Qh, Zhicheng Lian et autres

Abstract Cell–matrix interactions play a fundamental role in various biological processes and cellular functions. Although electrochemiluminescence (ECL) microscopy, particularly the negative ECL mode, offers a promising label-free approach for investigating cell–matrix interactions, its broader application is constrained by relatively low luminescence efficiency. …

cn (code pays fourni par la source)

Differential cellular and humoral immune responses of the Asian citrus psyllid Diaphorina citri to its ecto- and endoparasitoids

Zhuo Yu, Li Feng, Wenfeng Hu, Jun Zhong et autres

cn, fr (code pays fourni par la source)

The role of extracellular vesicles in the communication between endometrial cancer cells and tumour-associated macrophages: a review

Li Feng, Wei Shi

Endometrial cancer is a significant threat to the health of women worldwide. Extracellular vesicles are essential for the proliferation, migration, and invasion of cancer cells, whereas tumour-associated macrophages (TAMs) are key regulators of cancer development. The interaction between macrophages and extracellular vesicles …

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Tubular ACSM3 deficiency impairs medium-chain fatty acid metabolism and aggravates kidney fibrosis

Jinxi Li, Ting Xiang, Fengping Zhang, Li Feng et autres

Kidney fibrosis is driven by multiple factors, among which impaired fatty acid oxidation has emerged as a critical determinant. Acyl-Coenzyme A (CoA) synthetase medium-chain family member 3 (ACSM3), a key enzyme of medium-chain fatty acid (MCFA) metabolism, has been implicated in metabolic …

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Dynamic Characteristic (Axial Impedances) of a Novel Sandwich Flexible Insert with Fluid

Leipeng Song, Lulu Chang, Li Feng, Xinjian Xiang et autres

Piping systems can be analogized to the “vascular systems” of vessels, but their transmission characteristics often result in loud noises and large vibrations. The integration of flexible inserts within these piping systems has been shown to isolate and/or mitigate such vibrations and …

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M6A-METTL3-dependent nuclear PANC754/PSPC1/H3K4me1 repression complex regulate immune evasive LGALS7 signal to enhance immunotherapy against colorectal cancer

Jianfeng Zhang, Guilian Cao, Li Feng, Chenxi Wu et autres

Abstract Non-coding RNAs (ncRNAs) have important regulatory functions similar to traditional oncogenes or tumor suppressor genes. Our previous research found a novel pan-cancer downexpressed ncRNA, PANC754. However, its function and underlying mechanism remain obscure in colorectal cancer (CRC). In this study, in …

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Predicting brain amyloid load with digital and blood-based biomarkers

Wei–Neng Chen, Xinchong Shi, Fengjuan Su, Haifan Kong et autres

BACKGROUND: With the recent approval of anti-β-amyloid (Aβ) treatment for Alzheimer's disease (AD), a demand has emerged for scalable, convenient and accurate estimations of brain Aβ burden for the detection of AD that would enable timely, accurate and reliable diagnosis in one's …

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Single‐Molecule Electrochemiluminescence Imaging of Plasmonic Hot Spot Reactivity

Xuedong Huang, Qian Shi, Yanwei Lu, Binxiao Li et autres

Abstract Localized surface plasmon resonance (LSPR), an important optical property of noble metal nanomaterials, is extensively applied in electrochemistry. However, the specific LSPR effects on metallic nanoparticles are difficult to unravel and evaluate, owing to simultaneous factors like intrinsic electroactivity and surface …

cn, fr (code pays fourni par la source)

Single‐Molecule Electrochemiluminescence Imaging of Plasmonic Hot Spot Reactivity

Xuedong Huang, Qian Shi, Yanwei Lu, Binxiao Li et autres

Abstract Localized surface plasmon resonance (LSPR), an important optical property of noble metal nanomaterials, is extensively applied in electrochemistry. However, the specific LSPR effects on metallic nanoparticles are difficult to unravel and evaluate, owing to simultaneous factors like intrinsic electroactivity and surface …

cn, fr (code pays fourni par la source)

Enhanced Near-Infrared Light-Mediated Hydrogel Curing Using Photoinitiator Integrated Upconversion Particles as Nano Initiator for 3D Bioprinting

Xiong Xiao, Ziwei Huang, Liping Yang, Yu-Chu Yang et autres

In vivo three-dimensional (3D) bioprinting is a promising strategy that can enable personalized organ repair with minimal injury. The current in vivo 3D bioprinting based on upconversion nanoparticles (UCNPs) mediating near-infrared (NIR) light curing is still limited by the low hydrogel cross-linking …

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DNA Sensors for the Detection of Mercury Ions

Li Feng, Jinxin Lin, Éric Lichtfouse, Haifeng Qi et autres

Ecosystem pollution by mercury ions (Hg2+) is a major health concern, yet classical analytical methods for mercury analysis are limited. This paper reviews the advances in Hg2+ detection using DNA as recognition elements in the sensors. DNA as a recognition molecule is …

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DNA Framework-Based Lysosome-Targeting Chimeras: Intracellular ATP-Facilitated Extracellular Protein Degradation

Yujun Ning, Bin Li, Chen Wu, Li Feng et autres

Targeted protein degradation (TPD) offered a riveting therapeutic paradigm to eradicate pathogenesis-relevant proteins, especially those belonging to the once-considered undruggable proteome. Considering that adenosine triphosphate (ATP) is the primary energy source for cell activities and lysosomes are important ATP storage sites, herein, …

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