Chenglin Liu

A Retrieval-Augmented Multimodal Framework for Scientific Reasoning in Materials Science

Ziyi Luo, Jian Feng Xu, Qingbo Yan, Chenglin Liu

cn (code pays fourni par la source)

Integrated multiomic profiling of breast cancer in the Chinese population reveals patient stratification and therapeutic vulnerabilities

Leming M. Shi, Xi Jin, Wei Huang, François Bertucci et autres

us (code pays fourni par la source)

Bioinspired honeycomb-mimetic adaptive hyaluronic acid hydrogel composite scaffold: intelligent prevention and treatment of infection of bone implants and promotion of bone repair

Jiahao Fu, Hai Lan, Likun Liu, Lingling Zou et autres

Addressing two major challenges in the field of bone implants: bacterial infection and delayed bone fusion, this study draws inspiration from the beehive structure to develop an adaptive enzyme-responsive hydrogel composite scaffold. The scaffold composed of an intermittently 3D low-temperature deposition printing …

cn (code pays fourni par la source)

Landscape of gene fusions in hormone receptor-positive breast cancer reveals ADK fusions as drivers of progression and potential therapeutic targets

Yang Ou-Yang, Ding Ma, Cai‐Jin Lin, Yun‐Song Yang et autres

Gene fusions are becoming critical oncogenic drivers with potential therapeutic relevance across various cancers. However, their roles and clinical implications in breast cancer remain largely unexplored. In this study, we leveraged a large-scale multiomics cohort and a drug screening platform for breast …

cn (code pays fourni par la source)

TableCall: Boosting Table Question Answering with Tool-Driven Training-Free LLMs

Chun-Bo Xu, Yiming Chen, Xiao-Hui Li, Fei Yin et autres

cn (code pays fourni par la source)

DocSAM: Unified Document Image Segmentation via Query Decomposition and Heterogeneous Mixed Learning

Xiaohui Li, Fei Yin, Chenglin Liu

Document image segmentation is crucial for document analysis and recognition but remains challenging due to the diversity of document formats and segmentation tasks. Existing methods often address these tasks separately, resulting in limited generalization and resource wastage. This paper introduces DocSAM, a …

cn (code pays fourni par la source)

Spatial determinants of antibody-drug conjugate SHR-A1811 efficacy in neoadjuvant treatment for HER2-positive breast cancer

Ding Ma, Lei-Jie Dai, Xiangrong Wu, Chenglin Liu et autres

cn (code pays fourni par la source)

Two Antihypertensive and Antioxidant Peptides Derived from Alaska Pollack ( Theragra chalcograma ) Skin: In Silico , In Vitro , and In Vivo Investigation

Jing Li, Duo Cai, Yong-Nian Zhai, Chenxi Wu et autres

This study aimed to identify and characterize two novel dual-functional peptides with antihypertensive and antioxidant activities from byproducts of Alaska pollock skin (APS). Results showed that fifty-nine peptides were identified from APS, of which two peptides, GP1 (GSAGPAGPSGPRGP) and GP2 (LGDARNSPAPP), were …

cn, us (code pays fourni par la source)

DocSAM: Unified Document Image Segmentation via Query Decomposition and Heterogeneous Mixed Learning

Xiaohui Li, Fei Yin, Chenglin Liu

Document image segmentation is crucial for document analysis and recognition but remains challenging due to the diversity of document formats and segmentation tasks. Existing methods often address these tasks separately, resulting in limited generalization and resource wastage. This paper introduces DocSAM, a …

Self-assembled injectable Icariin@ Ti3C2Tx/doxorubicin hydrogel preserving osteogenesis while synergizing photodynamic and chemodynamic therapy for osteosarcoma

Jiahao Fu, Hao Hui Chen, Yiqiao Zhao, Hongzhong Xi et autres

Local therapy involving injectable hydrogel systems loaded with doxorubicin (DOX) has garnered significant attention in the realm of osteosarcoma (OS) research. Nevertheless, it has been noted that the local delivery of high-dose DOX exerts a pronounced inhibitory impact on osteogenesis, which is …

cn (code pays fourni par la source)

Uncovering the role of microRNAs in esophageal cancer: from pathogenesis to clinical applications

Zhenglin He, Yanhong Ji, Yutong Yuan, Chenglin Liu et autres

Esophageal cancer (EC) presents substantial therapeutic challenges due to its high mortality rate and the tendency for diagnosis at advanced stages. Acknowledging the constraints of the existing current treatment paradigm, there is a pressing need for the development of innovative, targeted therapeutic …

cn, hk (code pays fourni par la source)

Copper homeostasis and pregnancy complications: a comprehensive review

Tong-Yu Peng, Chenglin Liu

cn (code pays fourni par la source)