Sang‐Jun Park

CHARMM-GUI Quick Bilayer: Simple and Intuitive One-Stop Membrane Bilayer Builder

Sang‐Jun Park, Wonpil Im

Molecular modeling and simulation play a crucial role in advancing our understanding of protein function at the molecular level, offering insights that complement experimental approaches. In particular, molecular dynamics (MD) simulations with explicit lipid bilayers have become essential for a molecular level …

us (code pays fourni par la source)

Asymptomatic tuberculosis detected in health screening predicts favourable outcome

Sang‐Jun Park, Hyung Woo Kim, Eung Gu Lee, Yeonhee Park et autres

Background: The clinical and prognostic implications of asymptomatic tuberculosis remain poorly understood. Methods: We conducted a multicentre prospective cohort study to evaluate the association between asymptomatic tuberculosis (TB) and treatment outcomes. Individuals with rifampicin-susceptible pulmonary TB were enrolled from the Cohort Study …

us, kr, jp, gb, Afrique du Sud (code pays fourni par la source)

Sparsely Labeled fMRI Data Denoising with Meta-learning-Based Semi-supervised Domain Adaptation

Keun-Soo Heo, Ji-Wung Han, Soyeon Bak, Bogyeong Kang et autres

kr, us, cn (code pays fourni par la source)

Regenerative effect of human cell-derived BMP-2 cultured within a collagen bone graft in a rat calvaria defect model

Keun‐Suh Kim, Euna Pi, Sang‐Jun Park, In-Young Choi et autres

-derived recombinant human BMP-2 are constrained by structural deficiencies and high-dose requirements, which increases the risk of adverse effects. In this study, we aimed to address these limitations by developing a novel approach leveraging genetically engineered human retinal pigment epithelial cells (ARPE-19) …

kr, ch (code pays fourni par la source)

BPS2025 - BioMembHub: An innovative cyberinfrastructure for membrane protein research

Stanislav Cherepanov, L. Ponoop Prasad Patro, Zigang Song, Sang‐Jun Park et autres

us (code pays fourni par la source)

OPRLM: A Web Tool and a Database for Positioning and Simulations of Proteins in Realistic Lipid Membranes

Sang‐Jun Park, Kyle A Schnitzer, Stanislav Cherepanov, L. Ponoop Prasad Patro et autres

Molecular dynamics (MD) simulations in explicit lipid bilayers enable modeling of protein-lipid interactions essential for membrane protein functions and regulation. The newly developed computational web tool, OPRLM (Orientations of Proteins in Realistic Lipid Membranes), automates the assembly of membrane protein structures with …

us (code pays fourni par la source)

Improving binding affinity prediction by emphasizing local features of drug and protein

Daejin Choi, Sang‐Jun Park

kr, jp (code pays fourni par la source)

CHARMM-GUI PDB Reader and Manipulator: Covalent Ligand Modeling and Simulation

Lingyang Kong, Sang‐Jun Park, Wonpil Im

us (code pays fourni par la source)

CHARMM-GUI normal mode analyzer

Sang‐Jun Park, Hyuntae Na, Wonpil Im

us (code pays fourni par la source)

Measuring hydrodynamic force and friction on lipid-anchored proteins

Leah Knepper, Gabriel R. Cuce, Emily Ankorm, Samuel Pash et autres

us (code pays fourni par la source)

Using CHARMM all-atom simulations to determine the force required to move lipid-anchored proteins

Gabriel R. Cuce, Leah E. Knepper, Emily Ankrom, Lingyang Kong et autres

us (code pays fourni par la source)

CCDC 2287760: Experimental Crystal Structure Determination

Zihang Deng, Melanie A. Padalino, Julius E. L. Jan, Sang‐Jun Park et autres

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, …