Qingyun Li

Corrigendum to “Xiao-Liu Tang (XLT), a traditional Chinese medicine formula that suppresses the progression of cervical cancer by inducing apoptosis and inhibiting cell migration” [J Ethnopharmacol. (2026) 358 120966]

Siying Dang, Xiaoxuan Tang, Qingyun Li, J Wu et autres

Figure S5 from Interleukin-34–Induced Arg1+ Macrophages Play a Key Role in Breast Cancer Brain Metastasis

Xiaoqing Cheng, Khooshbu Kantibhai Patel, Brandon Zhou, Yiwei Fu et autres

IL34 induced ARG1 expression in BV2 cells.

Figure 1 from Interleukin-34–Induced Arg1+ Macrophages Play a Key Role in Breast Cancer Brain Metastasis

Xiaoqing Cheng, Khooshbu Kantibhai Patel, Brandon Zhou, Yiwei Fu et autres

Organoid transplant model for HER2-positive BCBMs. A, MRI of a patient with HER2+ breast cancer shows two cerebellar metastases in the brain. B, Schema for establishing BCBM in mice. C, Dorsal and coronal brain slice views of the mouse cerebellum. D, Brightfield …

Data from Interleukin-34–Induced Arg1+ Macrophages Play a Key Role in Breast Cancer Brain Metastasis

Xiaoqing Cheng, Khooshbu Kantibhai Patel, Brandon Zhou, Yiwei Fu et autres

Abstract Brain metastases occur in up to 40% of patients with stage IV breast cancer, and the cerebellum is a common site for metastases in HER2-positive breast cancer. We developed a syngeneic, immunocompetent mouse model of breast cancer brain metastases (BCBM) by …

Figure 6 from Interleukin-34–Induced Arg1+ Macrophages Play a Key Role in Breast Cancer Brain Metastasis

Xiaoqing Cheng, Khooshbu Kantibhai Patel, Brandon Zhou, Yiwei Fu et autres

IL34-induced Arg1 expression at the invading edge in cerebellum metastasis of HER2+ breast cancer. A, Spatial feature plot of IL34 in a representative murine tissue sample. B, ELISA test result of IL34 protein level from astrocytes and microglial cells, HP breast cancer …

Figure S2 from Interleukin-34–Induced Arg1+ Macrophages Play a Key Role in Breast Cancer Brain Metastasis

Xiaoqing Cheng, Khooshbu Kantibhai Patel, Brandon Zhou, Yiwei Fu et autres

Spatial gene expression in mouse BCBM.

Table S2 from Interleukin-34–Induced Arg1+ Macrophages Play a Key Role in Breast Cancer Brain Metastasis

Xiaoqing Cheng, Khooshbu Kantibhai Patel, Brandon Zhou, Yiwei Fu et autres

Differentially Expressed Genes

Figure S4 from Interleukin-34–Induced Arg1+ Macrophages Play a Key Role in Breast Cancer Brain Metastasis

Xiaoqing Cheng, Khooshbu Kantibhai Patel, Brandon Zhou, Yiwei Fu et autres

IL34-induced ARG1 expression in macrophages at the invading edge of BCBM.

Figure 7 from Interleukin-34–Induced Arg1+ Macrophages Play a Key Role in Breast Cancer Brain Metastasis

Xiaoqing Cheng, Khooshbu Kantibhai Patel, Brandon Zhou, Yiwei Fu et autres

IL34 expression and CD163+ macrophages in human BCBM samples. A, IHC staining of human IL34 on human BCBM samples (N = 19). B, IF costaining of CD206 and IL34 on human BCBM samples (N = 8). C, CD163 IHC on human BCBM …

Figure 4 from Interleukin-34–Induced Arg1+ Macrophages Play a Key Role in Breast Cancer Brain Metastasis

Xiaoqing Cheng, Khooshbu Kantibhai Patel, Brandon Zhou, Yiwei Fu et autres

Spatial transcriptomics reveals the clusters of cells and genes in HER2+ BCBM. A, Sample joint clustering in the duplicate samples of spatial transcriptomics in the HER2+ breast cancer cerebellum metastasis model. The average expression of the whole genome in each cluster is …

Figure S1 from Interleukin-34–Induced Arg1+ Macrophages Play a Key Role in Breast Cancer Brain Metastasis

Xiaoqing Cheng, Khooshbu Kantibhai Patel, Brandon Zhou, Yiwei Fu et autres

Characterization of murine breast cancer organoids.

Figure S6 from Interleukin-34–Induced Arg1+ Macrophages Play a Key Role in Breast Cancer Brain Metastasis

Xiaoqing Cheng, Khooshbu Kantibhai Patel, Brandon Zhou, Yiwei Fu et autres

Effect of CSF1R blocking antibody and IL34 CRISPR knockout.