Chunlin Wang

Effects of Dietary Bacillus amyloliquefaciens TL106 on Growth Performance, Antioxidant Capacity, Immune Function and Intestinal Microbiota in Danzhou Chickens

xinlei wang, Peijie Du, Chong Xi, Yunhe Cao et autres

The study aimed to investigate the effects of Bacillus amyloliquefaciens TL106 (TL106) on growth performance, antioxidant capacity, immune function, and intestinal microbiota in Danzhou chickens. A total of 384 healthy female Danzhou chicks were randomly assigned to a control group (CON) and …

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PHLPP1 inhibition in vascular smooth muscle cells alleviates atherosclerotic plaque formation via up-regulating autophagy in ApoE−/− mice

Mingjun Zhang, Xiaobin Guo, Jiaxing Zhang, Xiangran Kong et autres

Abstract PH domain and leucine-rich repeat protein phosphatase1 (PHLPP1) is a recently identified serine/threonine protein phosphatase which plays a critical role in metabolic disorders through dephosphorylation of its downstream targets, but the association between PHLPP1 and atherosclerosis as well as vascular smooth …

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Dual inhibition of tubulin and DNMT by the novel letermovir derivative H62 blocks leukemia

Jian Gao, Fen Tian, Yao Tang, Hongqian Zhu et autres

Leukemia therapy, especially myelogenous leukemias, is often challenged by an aggressive nature, high relapse rate due to dormant stem cells, side effects, and drug resistance. Microtubules-targeting agents are often used as first-line therapy for various cancers, including hematological malignancies. However, limitations such …

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Effects of parathyroid hormone on bone augmentation in a rat model of orthodontic treatment: potential involvement of the non-PLC/PKC signaling pathway

Xiaolu Zhang, Minjie Li, Chunlin Wang, Qiuyu Wang et autres

This study investigates the effects of parathyroid hormone (PTH) on alveolar bone formation in a rat model of orthodontic treatment, with a specific focus on the non-phospholipase C (PLC)-dependent protein kinase C (PKC) activation pathway. Forty female Sprague-Dawley rats were randomly assigned …

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Parametric analysis and design approach of staged prestressed composite beams based on serviceability requirements

Zexuan Sun, Yong Zhao, 崔田霞, Bin Zeng et autres

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Comparison of mRNA-based and next-generation sequencing HPV assays in a population-based cervical cancer screening program in China

H W Zhang, H M Zhou, Mengting Li, Tuohetiguli Mutailipu et autres

OBJECTIVE: To evaluate and compare the diagnostic performance of the Food and Drug Administration-approved APTIMA® human papillomavirus (HPV) assay (E6/E7 mRNA-based) and the Mygene HPV-STI Assay (MHSA) in detecting cervical intraepithelial neoplasia (CIN) 2+ and CIN3+ lesions among Chinese women in a …

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Performance degradation of cross-shaped steel reinforced concrete columns under freeze-thaw cycles: An integrated experimental, numerical, and theoretical study

Weichen Wang, Xiang Huang, Junhua Li, Chunlin Wang et autres

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A Novel SOX10 Mutation in a Patient with Kallmann an Waardenburg Syndrome Type II: A Case Report

Yilin Zhu, Chunlin Wang

Introduction: Waardenburg syndrome (WS) is a disease characterized by congenital sensorineural hearing loss and pigmentary abnormalities, including hair and irises. Kallmann syndrome (KS) involves idiopathic hypogonadotropic hypogonadism (IHH) with anosmia. Certain SOX10 mutations were found in both WS and KS, suggesting SOX10 …

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CD4+ T cell receptor repertoire and antigen-specific T cell responses in people who “resist” infection of Mycobacterium tuberculosis 3108

Fei Gao, Mark M. Davis, Thomas J. Scriba, Chetan Seshadri et autres

Abstract Description Mycobacterium tuberculosis (Mtb) is the cause of tuberculosis that is usually transmitted through contact with TB patients. Several studies described “resisters” who exposed to Mtb for years but consistently negative for Mtb diagnosis, which assessed via IFNγ response to Mtb …

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Effects of Tetrabasic Zinc Chloride as Alternative to High Doses of Zinc Oxide on Growth Performance, Nutrient Digestibility, Intestinal Morphology, Immune Function, and Gut Microbiota in Weaned Piglets

Shuyu Peng, Nan Zhang, Yi Chen, Yongxi Ma et autres

This study aimed to investigate the effects of dietary supplementation with TBZC on the growth performance, diarrhea incidence, antioxidant ability, immune function, and intestinal health of weaned piglets. A total of 120 weaned piglets were randomly allocated to one of three dietary …

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Electrochemical-mediated FeS active sites regeneration for effective extraction of uranium from seawater

Zena Zhang, Chunlin Wang, Ruoyu Du, Jingjing Wang et autres

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Carbon source and electro-stimulation modulates performance, microbial ecology, and metabolism in U (VI) bioreduction systems

Chunlin Wang, Fan Chen, Jingjing Wang, Qi Huang et autres

Efficient removal and recovery of uranium from mining wastewater are essential for environmental protection and resource sustainability. Microbial reduction of soluble U(VI) to insoluble U(IV) is a promising strategy, but the role of biostimulation via tailored carbon sources and electrochemical inputs remains …

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