Pengcheng Shi

Efficacy and safety of sorafenib combined with Standard Chemotherapy in adult patients with Myeloid sarcoma: A multi-center, cohort study

Qian Li, Xi Jia, Guopan Yu, Danian Nie et autres

Abstract Background Currently, treatment for myeloid sarcoma (MS) primarily follows protocols of AML including standard chemotherapy and hematopoietic stem cell transplantation (HSCT), while most patients have a poor outcome. Sorafenib, a multitargeted tyrosine kinase inhibitor (TKI), has demonstrated promising antileukaemic activity in …

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Efficacy and Safety of cladribine combined with cytarabine and G-CSF in Eliminating Measurable Residual disease for Core-binding factor acute myeloid leukemia: A retrospective, single-arm, multicenter study

Qian Li, Xi Jia, Guopan Yu, Danian Nie et autres

Abstract Background Persistent measurable residual disease (MRD) in core-binding factor acute myeloid leukemia (CBF-AML) is closely associated with increased risk of relapse.This study aims to evaluate the efficacy and safety of cladribine combined with cytarabine and G-CSF (CLAG) regimen in eliminating MRD …

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Tunable sound absorption and energy absorption of origami-inspired metastructures

Zerui Shao, Yao Chen, Pengcheng Shi, Jinlong Wei et autres

Origami-inspired acoustic metastructures overcome limitations of conventional materials by integrating tunable geometric configurations. Here, we propose a set of origami honeycomb metastructures with Miura-ori and origami-bellow foldcores, achieving both frequency-adjustable sound absorption and high energy dissipation. Numerical simulations reveal that the Miura-ori …

Tunable sound absorption and energy absorption of origami-inspired metastructures

Zerui Shao, Yao Chen, Pengcheng Shi, Jinlong Wei et autres

Conventional acoustic and impact protection structures are often limited by fixed frequency bands and non-adjustable energy absorption properties. Recently, the ancient art of origami has inspired the design and fabrication of acoustic and energy-absorption mechanical metamaterials that address these limitations. Here, we …

Research on a phonocardiogram and electrocardiogram signal classification algorithm based on global group coordinate attention mechanism and multi-scale feature fusion

Guofu Wang, Yuhua Yang, Jiangong Cui, Wendong Zhang et autres

Purpose In recent years, the incidence of cardiovascular disease has continued to rise, and early screening and prevention are especially critical. Phonocardiography (PCG) and electrocardiography (ECG), as simple, cost-effective and non-invasive tests, are important tools for clinical analysis. However, it is difficult …

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MCAF-Net: A non-invasive early screening method for coronary artery disease based on a multi-scale cross-modal model

Fangyuan Chen, Jiangong Cui, Renxin Wang, Pengcheng Shi et autres

Coronary artery disease (CAD) is one of the leading causes of death worldwide. Achieving early, non-invasive, and highly accurate detection of CAD is crucial for reducing its mortality rate. This study utilizes a high-sensitivity MEMS-based PCG-ECG Synchronous Auscultation System to construct a …

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The necessity of enhancing the human health risk assessment of 1,3,6,8-tetrabromocarbazole: Based on in vitro experiments, theoretical calculations, and model predictions

Junchao Ma, Mengxi Ren, Jiangyan He, Pengcheng Shi et autres

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Legal Evalutions and Challenges of Large Language Models

Jiaqi Wang, Huan Zhao, Zhenyuan Yang, P. Shu et autres

In this paper, we review legal testing methods based on Large Language Models (LLMs), using the OPENAI o1 model as a case study to evaluate the performance of large models in applying legal provisions. We compare current state-of-the-art LLMs, including open-source, closed-source, …

Ginsenoside Rb1 improves human nonalcoholic fatty liver disease with liver organoids-on-a-chip

Hui Wang, Yue Zhu, Pengcheng Shi, Xiangyang Li et autres

Non-alcoholic fatty liver disease (NAFLD), a type of liver disease for which no treatment is currently approved, remains a major concern worldwide. It is manifested as simple hepatocyte steatosis and can develop into inflammation, fibrosis, cirrhosis and liver cancer in severe cases. …

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Where is VALDO? VAscular Lesions Detection and segmentatiOn challenge at MICCAI 2021

Carole H. Sudre, Kimberlin Van Wijnen, Florian Dubost, Hieab H.H. Adams et autres

Imaging markers of cerebral small vessel disease provide valuable information on brain health, but their manual assessment is time-consuming and hampered by substantial intra- and interrater variability. Automated rating may benefit biomedical research, as well as clinical assessment, but diagnostic reliability of …

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udPINNs: An Enhanced PDE Solving Algorithm Incorporating Domain of Dependence Knowledge

Nanxi Chen, Jiyan Qiu, Pengcheng Shi, Wu Yuan et autres

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Biomedical image analysis competitions: The state of current participation practice

Matthias Eisenmann, Annika Reinke, Vivienn Weru, Minu D. Tizabi et autres

The number of international benchmarking competitions is steadily increasing in various fields of machine learning (ML) research and practice. So far, however, little is known about the common practice as well as bottlenecks faced by the community in tackling the research questions …

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