Yuqian Zhang

A systemic epithelial–immune–neural framework for pediatric atopic dermatitis–allergic rhinitis comorbidity

Suning Mu, Yijie Wang, Wen Qin, Mengying Mao et autres

Atopic dermatitis (AD) and allergic rhinitis (AR) commonly coexist in childhood and are associated with an important clinical burden. Their frequent coexistence and substantial mechanistic overlap suggest that pediatric AD-AR comorbidity may involve patterns more complex than simple co-occurrence. However, existing models …

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Lactic Acid Bacteria-Derived γ-Aminobutyric Acid: From Targeted Screening and Biosynthesis to Functional Food Applications and Health Benefits

Yuqian Zhang, Xue Zhou, Dan Zheng, Xuezhi Yuan et autres

γ-Aminobutyric acid (GABA) is a non-proteinogenic amino acid that acts as a major signaling molecule across the nervous, cardiovascular, and immune systems. While GABA has historically been produced via chemical synthesis or plant extraction, microbial fermentation using lactic acid bacteria (LAB) provides …

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Conductive and stability-enhanced lanthanide complex electrochemiluminescence emitter and its application in sensitive detection of microRNA-21

Cun Wang, Yuqian Zhang, Shaohan Xu, Yan Wen et autres

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The signaling mechanism of phyA involves direct interaction with ATG8 to regulate HY5 autophagic degradation under nutrient starvation

Lu Jiang, Shilong Zhang, Huishan Liu, Ran Zhao et autres

Phytochrome A (phyA), the only far-red light (FRL) photoreceptor, initiates photomorphogenesis under FRL. Autophagy, an evolutionarily conserved degradation pathway, facilitates plant adaptation to nutrient stress. Recent studies revealed that elongated hypocotyl 5 (HY5) undergoes autophagic degradation during carbon and nitrogen starvation, a …

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Multi-objective aerodynamic optimization and flow mechanism investigation of centrifugal compressor impeller based on ANN and NSGA- III

Yuqian Zhang, Jiabin Mao, J F Chen, Yue Shu et autres

Semi-open centrifugal impellers are crucial parts of industrial compressors, as their aerodynamic performance directly influences the energy efficiency and operational stability of the system. The current optimization research faces major challenges: substantial computational costs for high-dimensional multi-objective optimization, susceptibility to local optima, …

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Increased 30‐s Arm Curl Frequency Can Reduce the Risk of Type 2 Diabetes Mellitus in Older Adults: A Cohort Study From Wuhan, Central China

Yuqian Zhang, Chengjing Huang, Liang Wang, Xi Zhang et autres

INTRODUCTION: This study aimed to investigate the association between performance on the 30-s arm curl test and the risk of new-onset type 2 diabetes mellitus (T2DM) in older adults. METHODS: In this prospective cohort study, community-dwelling adults aged ≥ 65 years in …

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Association of body mass index trajectories with incidence of stroke among elderly Chinese adults: a 10-year cohort study

Xi Zhang, Yuqian Zhang, Wei Li, Yaxuan Zhou et autres

Background: Limited data exists on relationship between body mass index (BMI) trajectory and stroke risk among elderly Chinese individuals. This study aimed to examine the association of BMI trajectory with stroke among people aged 65 years and older in China. Methods: 150, …

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Effect of hydrogen blending ratio on the aerodynamic performance and transient characteristics of natural gas centrifugal compressors

Ming Zhu, Yuqian Zhang, Fengyu Li, Zhengdao Wang et autres

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Effect of integrated combustor–vane configurations on inlet hot streak behavior and aerodynamics of axial turbine

Guojin Zhang, Zhiyuan Gao, Yuqian Zhang, Zhengdao Wang et autres

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Metabolomic and Transcriptomic Analyses Reveal the Differential Response Model of Cultivated Tea and Wild Tea Resources against Pestalotiopsis theae

Meishan Fang, Feiyan Wang, Lijie Wang, R. Zhang et autres

Tea gray blight caused by Pestalotiopsis theae threatens tea production. We investigated the differential responses in two cultivated (“JX”, “YJ”) and two wild tea resources (“R”, “S”) via metabolomics, transcriptomics, and in vitro analyses. Phenotypically, resistance ranked “JX” > “R” > “YJ” …

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Water-Dispersible Plasmonic Gold Nanoparticle Vesicle as a Drug Delivery Carrier for Cancer Therapy

Jinjian Wei, Xinjie Wang, H. K. Xu, Yi Yu et autres

Fabrication of water-dispersible plasmonic gold nanoparticle vesicles (GNVs) by using small-molecule surface ligands for biological applications still remains a significant challenge. In this paper, we demonstrate that a tri(ethylene glycol) terminated octafluoro-4,4′-biphenol ligand (TrOFBL) can self-assemble with 5 or 10 nm gold …

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Specificity of reward-based attention bias modification for depression in left-behind adolescents

Jiaxin Peng, Wen Xiao, Yuqian Zhang, Jiamin Li et autres

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