Fan He

Online-dominant self-management is associated with lower, while hybrid mode is associated with higher, quality of life: a community-based cross-sectional study

Xuanyu Wang, Fan He, Qinli Zhang, Yang Meng et autres

Background Health-related quality of life (HRQoL) is an important outcome measure for evaluating community health interventions. Exploring effective community-based health self-management strategies is of practical significance in the context of population aging. This study compared the associations of different activity delivery modes …

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Case Report: A rare case of Pneumocystis jirovecii infection with left hydropneumothorax following immunotherapy for stage IVB clear cell renal cell carcinoma

Li Jiang, Tao Ye, Haibo Cai, Fan He

Background: Pneumocystis jirovecii pneumonia (PJP) is an opportunistic infection that predominantly affects immunocompromised individuals, most commonly HIV-infected patients with significantly reduced CD4+lymphocyte counts, and is associated with high clinical mortality. Currently, there are few reports of pneumothorax secondary to PJP, and most …

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Retinoid X receptor γ interacts with peroxisome proliferator-activated receptor-γ to promote browning during adipose tissue differentiation

Defei Chen, Saed Woraikat, Xiong Guo, Fuyu Yang et autres

Obesity and type 2 diabetes mellitus are global public health challenges. Activating thermogenic adipose tissues, such as brown adipose tissue and beige adipose tissue, could be a promising strategy to combat obesity and consequently obesity-related diabetes. Both peroxisome proliferator-activated receptor-γ (PPARγ) and …

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Saliva MicroAge: A salivary microbiome based machine learning model for noninvasive aging assessment and health state prediction

Tiansong Xu, Yuting Niu, Chenyu Deng, YH Cheung et autres

Saliva MicroAge is a machine learning-based model designed to estimate biological age and assess health status using globally sourced salivary microbiome data. Trained on 4532 healthy samples, the model achieves high accuracy in predicting chronological age and captures health-related deviations (MicroAgeGap) in …

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Impact of previous abdominal surgery on minimally invasive radical resection of colorectal cancer: A meta-analysis

Fan He, Defei Chen

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Chinese Expert Consensus on Integrated Chinese and Western Medicine for the Treatment of Tic Disorders

Rong Ma, Sumei Wang, Yi Zheng, Jianmin Chen et autres

OBJECTIVE: Tic disorders are neurodevelopmental conditions that manifest in childhood or adolescence and can significantly impact the quality of life of affected children and their families to varying degrees. Integrated traditional Chinese and Western medicine treatment strategies have demonstrated more pronounced efficacy …

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Research Progress on the Material Basis of Traditional Chinese Medicines Based on Chemical Biology Methods

Xinyue Bai, Huimin Lin, Ziqi Yang, Fan He et autres

The chemical biology method is a cutting-edge technology that utilizes chemical research methods and ideas to study life and biomedicine at the molecular level. Recently, it has gradually been applied to screening chemical markers in traditional Chinese medicines. This article reviews the …

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Assessment of stress hyperglycemia ratio to predict all-cause mortality in patients with critical cerebrovascular disease: a retrospective cohort study from the MIMIC-IV database

Yuwen Chen, Jian Xu, Fan He, Jie Wang et autres

BACKGROUND: The association between the stress hyperglycemia ratio (SHR), which represents the degree of acute stress hyperglycemic status, and the risk of mortality in cerebrovascular disease patients in the intensive care unit (ICU) remains unclear. This study aims to investigate the predictive …

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Study on the correlation between alkaloids and tastes of Coptis Rhizome from four species based on UHPLC-QQQ-MS/MS combined with electronic tongue technique

Yu‐Feng Huang, Wenhui Luo, Wenhan Pei, Dongmei Sun et autres

Objective Taste is one of the vital indicators for the quality evaluation of Coptis rhizome (CR), but the traditional taste evaluation lacks objectivity. By establishing the correlation between CR’s tastes and alkaloids, an objective basis for the taste evaluation was established. Methods …

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UHPLC-QQQ-MS/MS method for the simultaneous quantification of 18 amino acids in various meats

M.Z. Wang, Junxiu Guo, Huimin Lin, Dawei Zou et autres

Amino acids are an essential source of human protein, and their content and composition are the main factors determining food protein utilization rate. Determining amino acids is essential in the component analysis of food. Therefore, a groundbreaking technique was developed utilizing ultra-high …

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Obstructive sleep apnea comorbid with insomnia symptoms and objective short sleep duration is associated with clinical and preclinical cardiometabolic risk factors: Clinical implications

Slobodanka Pejovic, Alexandros N. Vgontzas, Julio Fernández‐Mendoza, Fan He et autres

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Laparoscopic gastrectomy versus open gastrectomy for gastric cancer in patients among octogenarians: a meta-analysis

Fan He, Junjie Xiong, Hongjiang Liu, Chenglin Tang et autres

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