Meng Jiang

Metabolomic alterations in the plasma of patients with various clinical manifestations of COVID-19

Xin Qi, Xiao Liang, Jin Yang, Xiaorui Wang et autres

BACKGROUND: The metabolomic profiles of individuals with different clinical manifestations of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection have not been clearly characterized. METHODS: We performed metabolomics analysis of 166 individuals, including 62 healthy controls, 16 individuals with asymptomatic SARS-CoV-2 infection, …

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Recent Progresses in the Multimodality Imaging Assessment of Myocardial Fibrosis

Han Zhu, Kewei Xie, Yingying Qian, Zhiguo Zou et autres

Myocardial fibrosis, a common pathophysiological consequence of various cardiovascular diseases, is characterized by fibroblast activation and excessive deposition of extracellular matrix (ECM) collagen. Accumulating evidence indicates that myocardial fibrosis contributes to ventricular stiffness, systolic and diastolic dysfunction, and ultimately leads to the …

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Reply

Hang Zhao, Xiao-Chuan Cai, Meng Jiang, Jing Ma et autres

An MRI-based Radiomics Approach to Improve Breast Cancer Histological Grading

Meng Jiang, Chang-li Li, Xiaomao Luo, Zhi-Rui Chuan et autres

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The trends of maternal mortality ratios and cause pattern in 34 Chinese provinces, 1990–2017

Chang-li Li, Meng Jiang, Ke-cheng Huang, Jian Li et autres

BACKGROUND: Understanding the trends and causes to the burden of maternal deaths is a key requirement to further reduce the maternal mortality ratio (MMR), and devise targeted intervention policy. We aimed to evaluate the spatiotemporal trends of MMRs and cause patterns across …

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Application Value of MRI Combined with MSCT in Diagnosis and Staging of Colon Carcinoma

Zhiwei Zhao, Yong Chun Zhou, Meng Jiang, Ling Dang

Objective: To clarify the application value of magnetic resonance imaging (MRI) combined with multislice spiral computed tomography (MSCT) in the diagnosis and staging of colon carcinoma (CC). Methods: A total of 103 patients with histopathologically diagnosed CC were enrolled. Patient clinical and …

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Distinct miRNAs associated with various clinical presentations of SARS-CoV-2 infection

Qiqi Zeng, Xin Qi, Junpeng Ma, Fang Hu et autres

MicroRNAs (miRNAs) have been shown to play important roles in viral infections, but their associations with SARS-CoV-2 infection remain poorly understood. Here, we detected 85 differentially expressed miRNAs (DE-miRNAs) from 2,336 known and 361 novel miRNAs that were identified in 233 plasma …

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Functional CAD-RADS using FFRCT on therapeutic management and prognosis in patients with coronary artery disease

Chun Xiang Tang, Hong Yan Qiao, Xiao Lei Zhang, Meng Jiang et autres

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One-year outcomes of CCTA alone versus machine learning–based FFRCT for coronary artery disease: a single-center, prospective study

Hong Yan Qiao, Chun Xiang Tang, Uwe Joseph Schoepf, Richard R. Bayer et autres

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The bioequivalence of a single dose of a generic solifenacin succinate tablet or Vesicare in fasting or postprandial healthy Chinese adults

Hao Jin, Liping Shi, Jun-Gang Yin, Jingmei Yu et autres

OBJECTIVE: The present study evaluated the bioequivalence of the test preparation (5 mg generic solifenacin succinate tablet, produced by Jiangsu Deyuan Pharmaceutical Co., Ltd.) or the reference preparation (5 mg solifenacin succinate tablets with the trade name Vesicare, produced by Astellas Pharma …

Bioequivalence of daclatasvir hydrochloride tablets in healthy Chinese subjects

Liping Shi, Xue Feng Yang, Fang Liu, Jun-Gang Yin et autres

OBJECTIVE: The aim of the present study was to evaluate the bioequivalence and safety of two types of daclatasvir hydrochloride tablets administered to healthy Chinese subjects under fasting and postprandial conditions. MATERIALS AND METHODS: A total of 72 healthy Chinese subjects were …

A biomarker-based age, biomarkers, clinical history, sex (ABCS)-mortality risk score for patients with coronavirus disease 2019

Meng Jiang, Changli Li, Zheng Li, Wenzhi Lv et autres

Background: Early identification and timely therapeutic strategies for potential critical patients with coronavirus disease 2019 (COVID-19) are of crucial importance to reduce mortality. We aimed to develop and validate a prediction tool for 30-day mortality for these patients on admission. Methods: Consecutive …

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