Wenhao Zhou

Chemical components with antitumour activity from Inula britannica

Wenhao Zhou, Yijie Cai, Xilei Wang, Yijun Tu et autres

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Covalently Self-Polymerized Bioactive Poly(dopamine–silicon) Nanoplatform Reprograms Macrophage Metabolism, Modulates Redox Homeostasis, and Promotes Efficient Angiogenesis for Inflammation Injury Repair

Yidan Wang, Ting Li, Tongtong Leng, Meng Luo et autres

The inflammation-related tissue injury repair is still a challenge, in which the metabolic disturbance of macrophages induces cascade amplification of inflammatory mediators and hinders tissue repair. Herein, we developed covalently self-assembled poly(dopamine-silicon) nanoparticles (DS NPs) that integrate enzyme-mimetic catalysis with bioactive ion …

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Synergistic antibacterial and osteogenic properties of micro-arc oxidation GO@Ag/SF composite coatings for the repair of infectious bone defects

Wanliang Yang, Jingwei Bi, Xinxin Ji, Tian Bai et autres

Background: Bacterial infection and insufficient osseointegration of titanium-based implants remain major clinical challenges. Conventional drug-loaded coatings often fail to simultaneously achieve long-term antibacterial activity and the construction of an osteogenic microenvironment. Methods: volume ratio, the antibacterial and osteogenic performances of the coatings …

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Investigation on co-pyrolysis of oily sludge and polyethylene model compounds for enhancing pyrolytic oil quality using reactive force field molecular dynamics simulation

Zejian Ai, Lijian Leng, Qian Li, Wenhao Zhou et autres

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HSF1-UCHL1 transcriptional axis protects against MASLD via regulation of PPARα protein stability

Yuxiang Cao, Xiangcheng Fan, Meiyao Meng, Yingwen Wang et autres

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Biodegradable Zn‐Based Implants: Progress, Challenges, and Pathways toward Clinical Translation

Panfeng Zhao, Zhengquan Wang, Hui Yang, Xiyuan Zhang et autres

As a new generation of biomaterials, biodegradable zinc (Zn)-based implants hold substantial promise for clinical use due to their favorable biocompatibility and controllable degradation behavior. This review summarizes recent progress in Zn-based implants, focusing on the physiological roles of Zn, current Zn-based …

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“Even if I do it, I cannot see any differences”: Designing Strategies to Facilitate Adolescents’ Low-Carbon Behavior

Rui Shan, Wenhao Zhou, Huanshu Jiang, Wei Zhang

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A Zn 2+ -Coordinated, HA-Reinforced Hierarchical Cellulose-Based Composite Hydrogel with Multifunctions

Weimin Zhang, Mi Chen, Xiaotong Lu, Jianfei Liu et autres

Current bone repair materials struggle to integrate mechanical support, bioactivity, and antibacterial function, particularly those capable of mimicking the multiscale structure and regulating the local ionic microenvironment of natural bone. Herein, a biomimetic multilevel composite hydrogel based on a natural luffa sponge …

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Ag-enhanced β titanium alloys for surgical implants: microstructural regulation achieves superior strength, corrosion resistance and biocompatibility

Xiqun Ma, Yufei Tang, Sen Yu, Wenhao Zhou et autres

β-titanium alloys attract great interest in surgical implants due to its low elastic modulus. The addition of Ag further enhances the strength, ductility, corrosion resistance and biocompatibility of such alloys, which optimizes their compatibility with human bones. In this study, Ti-15Mo-xAg (x …

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Tailoring the microstructure of biodegradable Zn-Cu-Li wires via thermo-mechanical processing towards high-performance surgical staples

Xiyuan Zhang, Zilong Wang, Chun Chen, Wenhao Zhou et autres

Although biodegradable Zn alloy fine wires are promising for staples, most exhibit inadequate mechanical properties, and current studies remain preliminary. In this work, Zn-2Cu-0.8Li (wt%) alloy fine wires (0.22 mm) for staples with outstanding mechanical properties were fabricated via hot extrusion, multi-pass …

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Roles of plant-derived natural compounds in the prevention and treatment of osteoporosis

Ziyi Duan, Wenhao Zhou, Yingjie Cai, Min Zhong et autres

Osteoporosis is a systemic disease, and epidemiological projections indicate that by 2050, approximately 23.43% of the Chinese population over 50 years of age will be affected. Given the poor prognosis associated with osteoporosis, the exploration of safe and effective natural products is …

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Laser rapidly fabricated amorphous/crystalline Mg-Zn-Ca biodegradable alloys: hetero-structure, corrosion behavior and antibacterial effect

Wei Wang, Jiapeng Ren, Xuehua Wu, Wenhao Zhou et autres

• A near-fully dense part with a heterogeneous microstructure was fabricated by LPBF. • It consisted primarily of amorphous matrix (>80%) with a few of nanocrystalline phases. • Dense Zn-rich corrosion product layer effectively delayed the degradation of Mg matrix. • Massive …

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