Bin Peng

Physiological and transcriptomic analyses reveal the effect of exogenous chitosan oligosaccharides on ‘Harumi’ fruit resistance to Penicillium digitatum

Mingfei Zhang, Xu Zou, Jiahuan Liu, Yuping Wang et autres

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Laminin β1 stimulates the Hippo-YAP1 pathway to advance the progression and lenvatinib resistance in hepatocellular carcinoma

Zhiliang Cai, Jinjin Li, Long Wu, Xinyi Hu et autres

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Effect of exogenous glucose and sucrose on quality maintenance of 'Huangguogan' fruit during postharvest storage

Mingfei Zhang, Kexin Liu, Yu Wang, Shanghong Chen et autres

Citrus fruits are susceptible to postharvest quality deterioration. While exogenous sugar treatments have shown potential for modulating postharvest physiology, their mechanistic actions in citrus remain poorly defined. This study investigated the effects of exogenous sucrose and glucose on the postharvest quality of …

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Analysis of sugar components and identification of SPS genes in citrus fruit development

Wen Lu, Wenhui Hao, Kexin Liu, Jiahuan Liu et autres

Sugar is a primary determinant of citrus fruit flavour, but undergoes varied accumulation processes across different citrus varieties owing to high genetic variability. Sucrose phosphate synthase (SPS), a key enzyme in glucose metabolism, plays a crucial role in this context. Despite its …

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coRIC map: a framework for the exploration of multifaceted subcellular RNA-binding proteins

Yuan Lv, Xiangpeng Guo, Jieyi Hu, Shahzina Kanwal et autres

Abstract The ability of RNA-binding proteins (RBPs) to form complexes with other biomolecules underpins a broad range of functions and remarkable structural properties. Understanding the precise spatiotemporal dynamics of RBPs and their interacting partners in the steady state and upon perturbation is …

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Pan-glioma analyses reveal species- and tumor-specific regulation of neuron-glioma synapse genes by lncRNAs

Wei Xiong, Xuecong Zhang, Bin Peng, Hao Zhu et autres

Gliomas are highly heterogeneous and aggressive. Malignant cells in gliomas can contact normal neurons through a synapse-like structure (called neuron-to-glioma synapse, NGS) to promote their proliferation, but it is unclear whether NGS gene expression and regulation show species- and tumor-specificity. This question …

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Supplementary figures from Genomic Analysis of Nasopharyngeal Carcinoma Reveals TME-Based Subtypes

Li Zhang, Kenzie D. MacIsaac, Ting Zhou, Pei-Yu Huang et autres

Supplementary Figures Figure S1: Subtype identification using random sub-sampling. Figure S2: Subtype robustness. Figure S3: Morphological evaluation of tumors. Figure S4: % Tumor content by subtype. Figure S5: Principle components analysis. Figure S6: Microenvironment signatures. Figure S7: Cytotoxic to T-cell signature ratio …

Supplementary figures from Genomic Analysis of Nasopharyngeal Carcinoma Reveals TME-Based Subtypes

Li Zhang, Kenzie D. MacIsaac, Ting Zhou, Pei-Yu Huang et autres

Supplementary Figures Figure S1: Subtype identification using random sub-sampling. Figure S2: Subtype robustness. Figure S3: Morphological evaluation of tumors. Figure S4: % Tumor content by subtype. Figure S5: Principle components analysis. Figure S6: Microenvironment signatures. Figure S7: Cytotoxic to T-cell signature ratio …

Screening of traditional Chinese medicine monomers as ribonucleotide reductase M2 inhibitors for tumor treatment

Yaya Qin, Song Feng, Xiaodong Zhang, Bin Peng

BACKGROUND: Ribonucleotide reductase (RR) is a key enzyme in tumor proliferation, especially its subunit-RRM2. Although there are multiple therapeutics for tumors, they all have certain limitations. Given their advantages, traditional Chinese medicine (TCM) monomers have become an important source of anti-tumor drugs. …

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Investigation of the binding behavior of bioactive 7-methoxyflavone to human serum albumin by coupling multi-spectroscopic with computational approaches

Qing He, Qi’er Mu, Zhongxun Wei, Bin Peng et autres

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Glucosamine‐phosphate N‐acetyltransferase 1 and its DNA methylation can be biomarkers for the diagnosis and prognosis of lung cancer

Peikun Ding, Bin Peng, Guofeng Li, Xuefeng Sun et autres

OBJECTIVE: Lung cancer ranking high in the cancer-related list has long perplexed patients, in which glucosamine-phosphate N-acetyltransferase 1 (GNPNAT1) is found to be highly expressed. Besides, DNA methylation is perceived as a biomarker to assess the prognosis of patients with various cancers. …

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The Microbiota and Cytokines Correlation between the Jejunum and Colon in Altay Sheep

Mengjun Ye, Meng Hou, Qimin Peng, Sheng Jia et autres

Both the jejunum and colon release cytokines that interact with intestinal microbiota. However, it is largely unclear which cytokines and microbial populations are involved in the homeostasis of the intestinal ecosystem for sheep health. To address this, we collected contents for isolating …

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