Zhilin Chen

DNA Barcoding Applications in Ants (Hymenoptera: Formicidae)

Jue Wang, Dongqing Liu, Zhilin Chen, Congcong Du

Taxonomy is fundamental to all organismic research. Therefore, the integration of molecular and morphological data is increasingly encouraged for more accurate species identification. However, the emphasis on and application of DNA barcoding methods appear to vary across different taxonomic groups. Ants, among …

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PHLPP1 deficiency alleviates dopaminergic neurodegeneration and represses neuroinflammation in Parkinson’s disease

Zhilin Chen, Yuan Liu, Jinyue Zhao, Xin‐Fu Zhou et autres

BACKGROUND: Pleckstrin homology (PH) domain leucine-rich repeat protein phosphatases (PHLPP) has been associated with several neurodegenerative diseases, however, few studies have investigated the role of PHLPP in Parkinson's disease (PD). The present study aimed to answer this question through establishing a Parkinson's …

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Author response for "High-Entropy Alloys and Oxides as Catalysts for Water-Splitting: Synthesis, Characterization, Applications and Prospect"

Tong Wu, Xiaoyi Zhang, Ziyu Yang, Zhilin Chen et autres

Protocol for a Randomized Controlled Trial to Enhance Executive Function via Brief Mindfulness Training in Individuals with Internet Gaming Disorder

Zhilin Chen, Jie Ge, Quan Gan, Yu Fu et autres

BACKGROUND: Internet Gaming Disorder (IGD) is characterized by uncontrolled gaming behavior, leading to emotional distress, neglect of academic or life responsibilities, and damage to interpersonal relationships, all of which have serious negative impacts on individuals and society. IGD has been associated with …

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High-entropy alloys and oxides as catalysts for water-splitting: synthesis, characterization, applications and prospects

Tong Wu, Xiaoyi Zhang, Ziyu Yang, Zhilin Chen et autres

This review provides an overview of recent advancements in high-entropy alloys and oxides for electrocatalysis, with a focus on their applications in the hydrogen evolution reaction, oxygen evolution reaction, and oxygen reduction reaction.

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Research on the Regulation Mechanism of Laser Shock Peening on SCC Performance of Thin-Walled Austenitic Welded Joints

Qianwu Li, Chengtao Li, Jing Wan, Zhaoguang Zhu et autres

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Use of DFIT Analysis Approach to PFPD in a Pilot: Preliminary Verification and Application

Z. Zhang, Xianlin Ma, Jie Zhan, C. M. Xiong et autres

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A novel micro-scale structure reconstruction approach for porous media and characterization analysis: An application in ceramics-based diesel particulate filter

Diming Lou, Zhilin Chen, Yunhua Zhang, Yu-qi Yu et autres

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Numerical simulation of diesel particulate filter flow characteristics optimization: From the perspective of pore structure parameters and inlet velocity

Diming Lou, Zhilin Chen, Yunhua Zhang, Yu-qi Yu et autres

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Chimeric antigen receptors enable superior control of HIV replication by rapidly killing infected cells

Yuqi Zhou, Julie K. Jadlowsky, Caitlin Baiduc, Alex W. Klattenhoff et autres

Engineered T cells hold great promise to become part of an effective HIV cure strategy, but it is currently unclear how best to redirect T cells to target HIV. To gain insight, we generated engineered T cells using lentiviral vectors encoding one …

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Intrathecal delivery of a bicistronic AAV9 vector expressing β-hexosaminidase A corrects Sandhoff disease in a murine model: A dosage study

Alex E. Ryckman, Natalie M. Deschenes, Brianna M. Quinville, Karlaina J.L. Osmon et autres

The pathological accumulation of GM2 ganglioside associated with Tay-Sachs disease (TSD) and Sandhoff disease (SD) occurs in individuals who possess mutant forms of the heterodimer β-hexosaminidase A (Hex A) because of mutation of the HEXA and HEXB genes, respectively. With a lack …

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Efficacy of Adeno-Associated Virus Serotype 9-Mediated Gene Therapy for AB-Variant GM2 Gangliosidosis

Meera Vyas, Natalie M. Deschenes, Karlaina J.L. Osmon, Zhilin Chen et autres

GM2 gangliosidoses are a group of neurodegenerative lysosomal storage disorders that are characterized by the accumulation of GM2 gangliosides (GM2), leading to rapid neurological decline and death. The hydrolysis of GM2 requires the specific synthesis, processing, and combination of products of three …

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