Shilin Chen

A telomere-to-telomere genome assembly of Asparagus cochinchinensis reveals the evolution of centromere and steroidal saponin biosynthesis

Mingjiang Huang, Yawen Yang, Liying Feng, Yun Peng et autres

Abstract Asparagus cochinchinensis is a perennial medicinal plant that accumulates bioactive steroidal saponins in enlarged tuberous roots, yet the genomic basis of its specialized metabolism and the regulatory mechanisms underlying steroidal saponin biosynthesis remain poorly understood. Here, we present the first telomere-to-telomere …

cn (code pays fourni par la source)

Biomimetic PD-1-MSCs membrane-engineered nanoparticles for enhanced blood-brain barrier penetration and anti- glioma therapy

Jie Li, Yuhao Gao, Wenbo Zhao, Huamin Zeng et autres

Objective Glioma is the most common and aggressive primary intracranial tumor. Its clinical management is substantially hindered by the blood–brain barrier (BBB) and the immunosuppressive tumor microenvironment (TME). This study aimed to construct PD-1-functionalized mesenchymal stem cell (MSC) membrane biomimetic nanoparticles co-loaded …

cn (code pays fourni par la source)

Artificial intelligence empowering innovation in traditional Chinese medicine

Wei Chen, Shilin Chen

cn (code pays fourni par la source)

Lignin Polymerization: Towards High-Performance Materials

Yan Li, Alberto J. Huertas-Alonso, H Liu, Lin Dai et autres

Preprint

cn, se (code pays fourni par la source)

Lignin Polymerization: Towards High-Performance Materials

Yan Li, Alberto J. Huertas-Alonso, H Liu, Lin Dai et autres

Preprint

cn, se (code pays fourni par la source)

Circumventing the energy gap law via an isomerization-aggregation strategy toward highly efficient solution-processed OLEDs

Xiang Chang, Fusheng Zhang, Bin Ma, Dingyuan Yan et autres

cn (code pays fourni par la source)

A Novel CsYABBY3‐CsAS1 Feedback Loop Coordinates Trichome Differentiation and Cannabinoid Biosynthesis in Cannabis sativa L.

Xuewen Zhu, Yaolei Mi, Xue Cao, Weiqiang Chen et autres

Glandular trichome development typically coincides with specialized-metabolite production, yet the regulatory mechanisms that synchronizes these processes remain elusive. We uncover a trichome-enriched CsYABBY3-CsAS1 transcriptional module that links glandular trichome differentiation with cannabinoid biosynthesis in cannabis. CsYABBY3, a FILAMENTOUS FLOWER (FIL)/YAB3-family transcription factor, …

cn (code pays fourni par la source)

A “Lung-Trap” Theranostic Strategy for Precision Management of Drug-Resistant Bacterial Pneumonia and Bacteremia

Yu Xia Hou, Dingyuan Yan, Weigeng Huang, Dengke Chen et autres

The escalating global crisis of antibiotic resistance demands the development of novel therapeutic strategies. This study proposes a “lung-trap” strategy that shifts the paradigm from systemic chemical eradication to localized physical interception and clearance. An engineered peptide conjugate, namely BTFR, selectively accumulates …

cn, us, hk, kr (code pays fourni par la source)

Circumventing the Energy Gap Law via an Isomerization-Aggregation Strategy toward Highly Efficient Solution-Processed OLEDs

Xiang Chang, F Zhang, Bin Ma, Dingyuan Yan et autres

cn, hk, sg (code pays fourni par la source)

Molecularly engineered cellulose: the next-generation sustainable polymer electrolyte material

Liyu Zhu, Hongbin Yang, Kun Liu, Wei Li et autres

This review provides a clear and detailed interpretation of the required properties for cellulose-mediated PEMs and the common design approaches across different applications.

cn (code pays fourni par la source)

The X-ray absorption spectroscopy for advanced battery systems

Kaijie Miao, Shilin Chen, Jiangqi Zhou

cn (code pays fourni par la source)

miRNA rco-MIR395a-p5_1ss8TC suppresses CsOMT957 expression leading to reduction in cannflavin A accumulation in Cannabis sativa L.

Yuxin Zhou, Kang Ning, Yongzhong Chen, Shuming Yang et autres

cn (code pays fourni par la source)