Jorge Sánchez

Deciphering Molecular Mimicry: An In Silico Exploration of Heat shock protein 70 Conservation and its Role in Cross-Reactivity.

Andrés Sánchez, ISAURA FIGUEROA CARO, Isabella Rodriguez Jimenez, Andres Cuello Arrieta et autres

Objectives To evaluate the sequence and structural conservation of heat shock protein 70 (HSP70) across different allergenic sources and to assess its potential role in molecular mimicry- mediated cross- reactivity . Additionally, conserved linear and conformational epitopes potentially involved in immune recognition …

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Evaluation of the clinical utility of medical tests in chronic urticaria

Jorge Sánchez, Ana M. Martín Caraballo, Elizabeth García

Route of Allergen Immunotherapy: A Global Look Into Physicians' Motivations

Carmen Vidal, Davide Caimmi, Pablo Rodríguez del Río, Óscar Lado‐Baleato et autres

BACKGROUND: Current Allergen Immunotherapy (AIT) guidelines provide no definitive guidance on route selection, whether subcutaneous (SCIT) or sublingual (SLIT). The primary objective of this study was to characterize real-world AIT prescription patterns, with emphasis on route selection, using a factor analysis approach …

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Relationship of NSAID-hypersensitivity and Chronic Urticaria. Clinical Implications

Jorge Sánchez, Ana Caraballo, Susana Diez

Abstract Purpose of Review In this review, we conducted a literature search seeking to better understand the relationship between chronic spontaneous urticaria (CSU) and nonsteroidal anti-inflammatory drugs hypersensitivity (NSAID-hypersensitivity) associated with NSAID exacerbated cutaneous diseases (NECD), its clinical course, and gain insight …

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Prevalence of adverse reactions and food allergies in Colombia: Cross-sectional national study

Jorge Sánchez, Laura Osorio, Javier Estarita, Leidy Álvarez et autres

Background: The prevalence of food allergy (FA) has been widely studied in developed countries but has been less explored in Latin American countries, where the population has unique cultural conditions, which influence different factors associated with the prevalence of FAs. Objective: We …

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Autoallergy in chronic rhinosinusitis and its clinical relevance

Jorge Sánchez, A Bernal Sánchez, Julian Arango, Dalgys Martínez et autres

Background: The presence of IgE autoantibodies against human proteins ("autoallergy") has been identified in different type 2 inflammation. Objective: The aim of this study was to evaluate the presence of autoallergy in chronic rhinosinusitis (CRS) and explore its clinical impact. Methods: Cross-sectional …

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Clinical Evolution of Acute Urticaria and Association With IgE Autoantibodies

Jorge Sánchez, Andres Sánchez Biol, Ana M. Martín Caraballo, Maria-Valentina Bedoya-Florez et autres

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Adverse Events of Biologics in Severe Asthma

Jorge Sánchez, Ana M. Martín Caraballo, Leidy Laura Beltrán Álvarez

Abstract Purpose of Review To summarize current evidence on the immediate and long-term safety profile of the available monoclonal biological therapy (MBT) approved for the treatment of severe asthma. Recent Findings Clinical trials and real-world studies have shown that MBT are generally …

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Long‐Term Efficacy and Safety of Ligelizumab as Re‐Treatment in Patients With Chronic Spontaneous Urticaria

Ana M. Giménez‐Arnau, Marcus Maurer, Adam Reich, Chia‐Yu Chu et autres

BACKGROUND: Chronic spontaneous urticaria (CSU) is a debilitating skin condition affecting approximately 1% of the global population, characterized by recurrent wheals, angioedema, or both for over 6 weeks without identifiable external triggers. METHODS: This Phase 3b multicentre, double-blinded followed by open-label extension …

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Comment on ‘Patients with acute and chronic spontaneous urticaria have similar autoantibody profiles: CHAPEAU pilot study’

Jorge Sánchez, Ana M. Martín Caraballo

We read with great pleasure the recent article by Bonnekoh et al. in the British Journal of Dermatology. This article opens a new path to a better understanding of the urticaria pathophysiology and the possible clinical implications of measuring auto-IgG or auto-IgE …

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Sexual Health in Atopic Dermatitis: Impact of Skin Clinical Control

Jorge Sánchez, Gabriel Montoya, Ana M. Martín Caraballo, María Fernanda Ordóñez et autres

BACKGROUND: Sexual health in patients with atopic dermatitis (AD) remains scarcely studied. Identifying the problematic of sexual health disorders (SHD) in AD and associated factors is important for the design and implementation of targeted interventions. OBJECTIVE: To describe the frequency of sexual …

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Key Predictors of Adherence to a Mobile Health App for Managing Chronic Spontaneous Urticaria

Hugo Viegas, Bernardo Sousa‐Pinto, Rafael José Vieira, Aisté Ramanauskaité et autres

BACKGROUND: Mobile health technologies may improve the management of chronic diseases, such as chronic spontaneous urticaria. However, effectiveness of mHealth tools largely depends on patient adherence, which can be influenced by various demographic, clinical, behavioural, psychosocial factors, and apps characteristics (appealing and …

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