Haiyan Sun

Correction to: Continuous Lumbar Sympathetic Blockade Enhances the Effect of Lumbar Sympatholysis on Refractory Diabetic Neuropathy: A Randomized Controlled Trial

Haiyan Sun, Mingwei He, Jinlei Pang, Xiangfei Guo et autres

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NCAM1 potentiates small cell lung cancer stemness and resistance to NK cell-mediated cytotoxicity

Jing Qi, Haiyan Sun, Yinli Yang, Jiaqi Zhang et autres

Abstract Intrinsic resistance of small cell lung cancer (SCLC) to immunotherapy underscores our limited understanding of how tumors can evade immune responses. Here we demonstrated that neural cell adhesion molecule 1 (NCAM1, also called CD56) facilitates disease progression, tumor stemness, and resistance …

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The relationship between obstructive sleep apnea and insulin resistance in patients with type 2 diabetes mellitus: a cross-sectional observational study

Haiyan Sun, Xiaotao Wu, Guoxian Ma, Junqing Liu et autres

Background: Increasing evidence suggests obstructive sleep apnea (OSA) is an independent risk factor for type 2 diabetes. Insulin resistance is the primary mechanism in the early stage of type 2 diabetes. The aim of this study was to assess the prevalence of …

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Mouse V(D)J Humanization Recapitulates human-like Severe SARS-CoV-2 Immune Imprinting

Niu Xiao, Fanchong Jian, Yutong Li, Ke Li et autres

Summary The mechanisms driving divergent SARS-CoV-2 immune imprinting in populations with distinct SARS-CoV-2 exposure histories remain unclear. However, conventional wild-type mouse models fail to recapitulate severe imprinting, even after potent ancestral-strain mRNA immunization, hindering imprinting-related mechanistic investigation and vaccine evaluation. Here, we …

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Letter to the Editor “Cross-Sectional Associations of Depressive Symptoms, Anxiety Symptoms, and Emotional Support Seeking with Lower Urinary Tract Symptoms and Bladder Health”

Anqi Sun, Huanhuan Wang, Haiyan Sun

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Lactate Metabolism in Intervertebral Disc Degeneration: Unveiling Novel Mechanisms Through Bioinformatics

Haiyan Sun, Mingwei He, Jinlei Pang, Xiangfei Guo et autres

ABSTRACT Background Intervertebral disc degeneration (IDD) is a widespread issue associated with chronic lumbar pain and disability. This study aimed to identify lactate metabolism‐related genes in IDD and elucidate their mechanistic roles in disease progression. Methods IDD datasets were analyzed using R …

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Impact of Pre-PCI Activated Clotting Time on Outcomes of Bivalirudin Versus Heparin During Primary PCI

Meili Liu, Yi Li, Zhenyang Liang, Miaohan Qiu et autres

Background The BRIGHT-4 trial demonstrated that procedural anticoagulation with bivalirudin followed by a median 3-hour high-dose infusion reduced the 30-day composite of all-cause mortality or Bleeding Academic Research Consortium (BARC) types 3 to 5 bleeding compared with heparin alone among patients with …

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A tetraphenylethylene fused hemicyanine fluorescent probe for detection of sulfur dioxide (SO2) derivatives and its practical applications

Hong‐Shui Lv, Haiyan Sun

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Advances in Anesthesia Techniques for Postoperative Pain Management in Minimally Invasive Cardiac Surgery: An Expert Opinion

Kexin Yuan, Boqun Cui, Duomao Lin, Haiyan Sun

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Research progress of post-acute sequelae after SARS-CoV-2 infection

Taiwei Jiao, Yuling Huang, Haiyan Sun, Lina Yang

SARS-CoV-2 has spread rapidly worldwide and infected hundreds of millions of people worldwide. With the increasing number of COVID-19 patients discharged from hospitals, the emergence of its associated complications, sequelae, has become a new global health crisis secondary to acute infection. For …

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Abstract 3817: Real-world clinical outcomes in patients with advanced ROS1+non-small cell lung cancer in the US

Reginald Villacorta, Saurabh Ray, Yong Yuan, Sushupta M. Vijapur et autres

Abstract Introduction: ROS1 rearrangements define a rare molecular subtype of non-small cell lung cancer (NSCLC), occurring in 1-2% of patients (pts) with advanced NSCLC (aNSCLC). Crizotinib and entrectinib received US approval for ROS1+ aNSCLC in March 2016 and August 2019, respectively. Few …

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How Extracellular Nano-Vesicles Can Play a Role in Sepsis? An Evidence-Based Review of the Literature

Xiaolin Jin, Haiyan Sun, Lina Yang

Sepsis is a systemic inflammatory reaction caused by infection. Severe sepsis can lead to multiple organ dysfunction, with a high incidence rate and mortality. The molecular pathogenesis of sepsis is complex and diverse. In recent years, with further study of the role …

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