Amit Kumar

Time Lost Is Brain Lost: Insights into Acute Ischaemic Stroke Delays in a Tertiary Care Super-speciality Centre in Jharkhand

Tannu Kumari, Yuvraj Sinha, Amit Kumar, Anupa Prasad et autres

Background Early hospital arrival is essential for timely thrombolysis in acute ischaemic stroke. However, many patients in low-resource settings continue to reach tertiary care centres beyond the recommended treatment window. Purpose To evaluate pre-hospital and in-hospital delays among patients with acute ischaemic …

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Inflammation and Stress: The Resemblance and Variance Between Atherosclerosis and Carcinogenesis—A Pilot Study

Varsha Suryan, Amit Kumar, Nimai Chand Chandra

While atherosclerosis is a disease of vascular hypercholesterolemia, reports have also shown the presence of intracellular hypercholesterolemia in cancer tumor cells. Since the dietary cholesterol in the blood vessel is the major source of intracellular cholesterol, a low blood cholesterol level is …

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Abstract 2432: Precision genomics in leukemiareveals mutational and fusion landscapes in South Asian patients driving clinical decisions

Puja Sinha, Amit Kumar, Shobit Gupta, Rama E. Chandran et autres

Abstract Background: The integration of next-generation sequencing (NGS) into routine diagnostic workflows is revolutionizing molecular characterization in cancer care, enabling precise detection of pathogenic variants and other fusion transcripts. Particularly in malignant haematological diseases, NGS has significantly enhanced diagnostic accuracy and prognostic …

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Survival Outcomes of Neck Management(s) Approaches in OSCC: A Systematic Review and Meta-analysis

Ankita Tandon, Kumari Sandhya, Narendra Nath Singh, Khushboo Gupta et autres

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Tuberculosis associated hemophagocytic lymphohistiocytosis (TB-HLH)-A case series and role of steroid pulse therapy & intravenous immunoglobulin (IVIG) in a critically ill TB-HLH patient

Rituparna Pal, Rishi Rana, Upendra Kumar, Vinay Soni et autres

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Efficacy and safety of the muscarinic receptor agonist KarXT (Xanomeline-Trospium) in schizophrenia: a systematic review, meta-analysis and Bayesian sensitivity analysis

Nikhil Sharma, Mahalaqua Nazli Khatib, R. Roopashree, Mandeep Kaur et autres

BACKGROUND: Schizophrenia significantly impacts global health, with existing treatments primarily focusing on positive symptoms and often causing considerable side effects. KarXT (Xanomeline-Trospium), a novel treatment combining xanomeline, a muscarinic M1/M4 receptor agonist, and trospium, targets a broader range of symptoms including negative …

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A note on extended distribution of an endemic Eragrostis tremula var. gajanandii (Poaceae) from Indian Desert and its IUCN Red List Assessment

C. S. Purohit, Amit Kumar, S. L. Meena

Prevalence of Malnutrition among Adolescent Tribal Girls in India: A Systematic Review and Meta-analysis

Litna George, Asha Kiran, Neelam Nalini, Manisha Kujur et autres

BACKGROUND: About 104 million tribal people make up India's total population, and among them, 4.7 million tribal children suffer from malnutrition. OBJECTIVES: This systematic review and meta-analysis aimed to determine the pooled prevalence of malnutrition among adolescent tribal girls in India. MATERIALS …

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Low titre of agroinoculum with prolonged incubation period and low auxin concentration in the regeneration media are the key to high frequency of transformation in climate-resilient Aus-type rice genotype Nagina 22

Amit Kumar, Priyanka, K. Jeevanandhan, Megha Kaushik et autres

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Effectiveness of sternal wiring versus plating on operative and postoperative recovery metrics in sternal fractures and sternotomies: A systematic review and meta-analysis

Mohammed Ahmed, Mahalaqua Nazli Khatib, R. Roopashree, Mandeep Kaur et autres

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Association between vascular endothelial growth factor and atrial fibrillation: a systematic review

Nikhil Sharma, Mahalaqua Nazli Khatib, R. Roopashree, Mandeep Kaur et autres

BACKGROUND: Atrial fibrillation (AF) is the most prevalent form of sustained cardiac arrhythmia, with vascular endothelial growth factor (VEGF) increasingly recognized for its potential role in the pathogenesis of AF through mechanisms involving atrial remodeling, inflammation, and fibrosis. This systematic review aims …

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Association Between SHBG Levels and Hypertensive Disorders of Pregnancy: A Systematic Review and Meta‐Analysis

Ajay Malvi, Muhammed Shabil, Mahalaqua Nazli Khatib, R. Roopashree et autres

ABSTRACT Sex hormone‐binding globulin (SHBG) regulates sex hormone availability and is influenced by metabolic factors. Variations in SHBG levels during pregnancy may affect the development of hypertensive disorders such as gestational hypertension (GH) and preeclampsia (PE). This systematic review and meta‐analysis explores …

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