Yan Dong

Association of the TREM‐1–STAT3 Axis With Stroke Severity and Functional Outcomes in Ischemic Stroke: A Prospective Case‐Control Study

Haohai Lin, Yan Dong, Zhangping He, Chao Qin et autres

BACKGROUND: Information regarding the signaling axis involving triggering receptor expressed on myeloid cells 1 (TREM-1) and its downstream mediator, signal transducer and activator of transcription 3 (STAT3), remains limited in ischemic stroke. We investigated the plasma levels of TREM-1 in patients with …

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Dual-engineered defect-rich molecularly imprinted zirconium metal organic framework platform for selective adsorption and ultrasensitive analysis of alternariol

Shi-Rong Sun, Lu Liu, Xia Wang, Yan Dong et autres

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Exercise training for myocardial ischemia reperfusion injury: Mechanism and clinical practice (Review)

Junwei Gao, Lingyao Li, Yan Dong, Zhiyi Zhang et autres

Myocardial ischemia reperfusion injury (MIRI) remains a key and difficult issue in the field of cardiovascular diseases, and its pathogenesis involves multiple aspects. Exercise can effectively improve MIRI, and the mechanisms include reducing oxidative stress and inflammatory responses, regulating mitochondrial function and …

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The impact of left atrial voltage abnormality on ablation outcomes in paroxysmal atrial fibrillation and its pre-procedural predictors: an observational retrospective study

Dongsheng Zhao, Yan Dong, Qiushi Chen, Gaoyuan Ge et autres

BACKGROUND: Left atrial (LA) localized voltage abnormality displayed by electro-anatomic mapping (EAM) has been established as a surrogate marker of atrial fibrosis (AF) which predicts post-ablation recurrence. This study investigates preoperative predictors of LA voltage abnormalities and assesses their impact on atrial …

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Regulatory Role of Tubulin Beta 1 in Oocyte Endoplasmic Reticulum Stress and Mitochondrial Integrity via Transforming Growth Factor‐β1 Signaling Pathway in Mice

Zhiyong Li, Yan Dong, Xiaoxia Lin, Xueyuan Zhou et autres

Enhancing the developmental competence and quality of oocytes cultured in vitro remains challenging, in part due to limited understanding of the structural and molecular regulators of oocyte maturation. Microtubules, as key components of the cytoskeleton, are essential for chromosome segregation and meiotic …

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The association between multimorbidity and intrinsic capacity among older adults: The mediating role of frailty

Lulu Xiao, Junzi Dong, Na Hu, Junyan Zeng et autres

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Wearable Photonic Device for Multiple Biomarker Sampling and Detection without Blood Draws

Zuan‐Tao Lin, Biswabandhu Jana, Sandeep Korupolu, Yifei Kong et autres

Needle-based blood draws or phlebotomy practice in clinics for centuries, often causing pain, discomfort, and inconvenience. Here, a wearable photonic device is presented by integrating a microlens array (MLA) and an optic microneedle array (OMNA) functionalized with immunobinding for safe and needle-free …

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Response‐adapted zanubrutinib and tislelizumab as a potential strategy to enhance CD19 CAR T‐cell therapy in relapsed/refractory large B‐cell lymphoma: A retrospective observational study

Rong Shen, Weiguo Cao, Wang Li, Lingshuang Sheng et autres

BACKGROUND: CD19 chimeric antigen receptor (CAR) T-cell therapy is a potential treatment for relapsed/refractory (R/R) large B-cell lymphoma (LBCL). The combination of targeted therapeutic strategies, particularly bruton tyrosine kinase inhibitor zanubrutinib and programmed death-1 inhibitor tislelizumab, may improve clinical outcomes and modulate …

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Author Correction: Causal relationship between inflammatory factors and gynecological cancer: a Bayesian Mendelian randomization study

Chunxiao Dang, Mengmeng Liu, Pengfei Liu, Jinxing Liu et autres

In the original version of this Article Chunxiao Dang and Mengmeng Liu were omitted as equally contributing authors. The statement now reads:

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Improved visualization of electron-density dual-energy computed tomography for lumbar disc disease over the standard gray-scale type and virtual noncalcium imaging

Peng-Feng Sun, Xiaoping Wu, Mingyong Gao, Xiaoyue Zhang et autres

Background: Dual-energy computed tomography (DECT) enhances tissue imaging characterization. However, no studies have evaluated the diagnostic accuracy of electron density (ED) for simultaneously displaying the lumbar disc and disc calcification. This retrospective study aimed to investigate the ability of ED to visualize …

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Wearable Photonic Device for Multiple Biomarker Sampling and Detection Without Blood Draws

Zuan‐Tao Lin, Biswabandhu Jana, Sandeep Korupolu, Yifei Kong et autres

Abstract Blood draws or phlebotomy using needles have been practiced in clinics for several centuries and it often causes pain, discomfort, and inconvenience. Herein, we create a wearable photonic device by integrating a microlens array (MLA) and an optic microneedle array (OMNA) …

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P1295 Transcriptional analysis of chronic enteropathy associated with SLCO2A1 gene at single-cell resolution

Yan Dong, Jianfeng Huang, Y Zhang, QiSen Wang et autres

Abstract Background Eight inflamed gastrointestinal tissue samples and one non-inflamed sample from six CEAS patients, along with three healthy controls, were analyzed using single-cell RNA sequencing (scRNA-seq). Cellular composition, transcriptional profiles, and intercellular communication networks were compared to reference datasets, including Crohn’s …

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