Wenxing He

Comparative modelling and MD-derived energetic fingerprints identify engineering hotspots in Purpureocillium lilacinum subtilisin-like S8 proteases

Xiujun Zhang, Li Liu, Qing Lv, X Cheng et autres

Subtilisin-like serine proteases (family S8) secreted by the nematophagous fungus Purpureocillium lilacinum are widely involved in virulence-related processes during nematode infection and are therefore potential targets for biocontrol enhancement. Here, nine extracellular S8A.139 proteases from P. lilacinum PLFJ-1 were analysed using a …

Comparative modelling and MD-derived energetic fingerprints identify engineering hotspots in Purpureocillium lilacinum subtilisin-like S8 proteases

Xiujun Zhang, Li Liu, Qing Lv, X Cheng et autres

Subtilisin-like serine proteases (family S8) secreted by the nematophagous fungus Purpureocillium lilacinum are widely involved in virulence-related processes during nematode infection and are therefore potential targets for biocontrol enhancement. Here, nine extracellular S8A.139 proteases from P. lilacinum PLFJ-1 were analysed using a …

Identification of LsPROG gene in Leymus secalinus and validation of its function in Arabidopsis thaliana

Xi Zhang, J Q Li, Di Zhao, Xueru Feng et autres

BACKGROUND: Leymus secalinus, a perennial grass in the Poaceae family, exhibits multiple stress resistances including drought, salt-alkali, and trampling tolerance, with developed rhizomes enabling adaptation to harsh environments such as sand dunes, thus holding significant value for grassland improvement and forage breeding. …

cn (code pays fourni par la source)

Bacillus Cereus C3 Addition Facilitates Carbohydrate Degradation and Earthworm Growth During Vermicomposting of Sewage Sludge

Tiantian Tian, Xinge Cui, Wenxing He, K. Liu et autres

cn (code pays fourni par la source)

CsMYB60 confers cucumber resistance to Pseudomonas syringae pv. lachrymans through both receptor‐like kinase CsFLS2 ‐dependent and ‐independent pathways

Jialin Li, Jingdan Zhang, Wei Liu, Hongmei Li et autres

Bacterial angular leaf spot (BALS), caused by Pseudomonas syringae pv. lachrymans (Psl), is a severe bacterial disease constraining the cucumber industry. However, few genes have been identified that regulate resistance to BALS in cucumber. Here, we identified a gene, CsFLS2, which encoded …

cn (code pays fourni par la source)

Transformer-Based Multi-label Protein Subcellular Localization Prediction

Wenhui Zhao, Yixin Zhong, Yi Cao, Yaou Zhao et autres

cn (code pays fourni par la source)

Engineering plant holobionts for climate-resilient agriculture

Nayanci Portal-González, Wenbo Wang, Wenxing He, Ramón Santos

The plant holobiont-an integrated unit of the host and its microbiome-has co-evolved through ecological and genetic interactions. Microbiome engineering offers a promising route to enhance resilience in response to climate stress, soil degradation, and yield stagnation. This review presents an integrated framework …

cn (code pays fourni par la source)

MSADeepLoc: Subcellular Localization Prediction Using MSA and Protein Language Model

Wenhui Zhao, Yixin Zhong, Yi Cao, Wenxing He et autres

Protein subcellular localization (PSCL) prediction is a key research area in bioinformatics. However, most existing models have ignored the homology and diversity among protein sequences, which can reveal the functional sequence segments and indirectly reflect the structure of the protein. Consequently, the …

cn (code pays fourni par la source)

Metabolome-driven microbiome assembly determining the health of ginger crop (Zingiber officinale L. Roscoe) against rhizome rot

Wenbo Wang, Nayanci Portal-González, Xia Wang, Jialin Li et autres

BACKGROUND: Plant-associated microorganisms can be found in various plant niches and collectively comprise the plant microbiome. The plant microbiome assemblages have been extensively studied, primarily in model species. However, a deep understanding of the microbiome assembly associated with plant health is still …

cn (code pays fourni par la source)

ResSepDTAF: improving protein-ligand binding affinity predictions with residual separable convolutions and sequence-structural integration

menglin chen, xiujun zhang, Yi Cao, Fengli Zhang et autres

Prediction of protein-ligand binding affinity holds significant guidance value in fields such as drug development and protein molecular design. This study proposes a novel deep learning model, ResSepDTAF, for predicting protein-ligand binding affinity. The model integrates depthwise separable convolutions and residual modules, …

cn (code pays fourni par la source)

Mining key genes associated with phosphorus deficiency through genome-wide identification and characterization of cucumber SPX family genes

Jialin Li, Linyue Hu, Qianqian Luan, Jingdan Zhang et autres

BACKGROUND: Proteins harboring the SPX domain are crucial for the regulation of phosphate (Pi) homeostasis in plants. This study aimed to identify and analyze the entire SPX gene family within the cucumber genome. RESULTS: The cucumber genome encompassed 16 SPX domain-containing genes, …

cn (code pays fourni par la source)

Insights into the microbial assembly and metabolites associated with ginger (Zingiber officinale L. Roscoe) microbial niches and agricultural environments

Wenbo Wang, Nayanci Portal-González, Xia Wang, Jialin Li et autres

Ginger, a vegetable export from China, is well-known for its spicy flavour and use in traditional Chinese medicine. By examining the interactions of ginger plants' microbiome and metabolome, we can gain insights to advance agriculture, the environment, and other fields. Our study …

cn (code pays fourni par la source)