Shi Yue

High modularity, more flexible and independent communication of brain networks after stroke

Zou Huai, Xin Yu, Kang Wu, Yuan Li et autres

Abstract Stroke is recognized as a network communication disorder. Advances in neuroimaging technologies have enhanced our comprehension of dynamic cerebral alterations. However, abnormal and adaptive brain activity patterns after stroke are still underexplored. We aim to identify dynamic patterns of network remodeling …

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Optimization and clinical application of the preconditioning regimen in the treatment of severe aplastic anemia with interfamilial haploidentical peripheral hematopoietic stem cell transplantation: A report of 26 cases

Feng Shuqing, Xue Hui, Wang Cui-min, Yanhong Yao et autres

Objective To evaluate the safety and efficacy of an further optimized pretreatment for the treatment of severe aplastic anemia (SAA) by haploidentical peripheral hematopoietic stem cell transplantation. Methods From July 2009 to July 2019, 26 SAA patients in the Affiliated Hospital of …

樹状突起細胞の高塩食加重多発性硬化過程における研究の進展【JST・京大機械翻訳】

Shi Yue

外傷後肘剛性の発生と進行の危険因子:688例の症例対照研究【JST・京大機械翻訳】

Qian Yun, Yu Shiyang, Shi Yue, Huang Hengye et autres

基于UHPLC-MS/MS苦参实定性定量及其入血成分分析

宿美凤, 雒晓梅, W. ming, 常晓燕 et autres

蛇床子素上调miRNA-9抑制BACE-1表达治疗阿尔茨海默病

蔺莹, Ying Lin, 姚璎珈, Yao Ying-jia et autres

目的 探讨蛇床子素上调miRNA-9治疗AD的作用机制。 方法 基因芯片技术筛选蛇床子素治疗后差异表达的microRNAs; 数据库和Cytoscape预测miRNA-9调控的靶基因；脂质体2000建立APP高表达的SH-SY5Y细胞模型，MTT法检测蛇床子素对细胞活力的影响；将miRNA-9抑制剂转入到APP高表达的SH-SY5Y细胞中，RT-PCR法检测各组miR-9、BACE-1 mRNA的表达情况；Western blot方法检测细胞中BACE-1蛋白的表达情况。 结果 数据库结果显示，蛇床子素调控的miRNA-9可以与BACE-1靶向结合。本实验成功建立APP高表达的SH-SY5Y细胞模型。MTT结果显示，50 μmol·L-1蛇床子素对细胞有较好的保护作用。RT-PCR结果显示，蛇床子素可以上调miR-9的表达，抑制剂组miRNA-9表达最低。与模型组相比，蛇床子素可以抑制BACE-1 mRNA和蛋白的表达，且抑制剂组的BACE-1 mRNA和蛋白表达最多。 结论 蛇床子素治疗阿尔茨海默病可能与上调miRNA-9，从而抑制BACE-1表达有关。

QTL Mapping of Hydrocyanic Acid Content in Sorghum-Sudangrass

Wu Guofang, Yu Zhuo, Qianqian Lu, Yu XiaoXia et autres

Legal Reflection on the Direct Presumption of Medical Fault

Zhao Zijun, Shi Yue

脳出血早期血腫拡大危険因子に関する研究【JST・京大機械翻訳】

Shi Yue, Wang Desheng, Zhang Xin

異なる厚さの岩盤破断モード実験研究【JST・京大機械翻訳】

Jianping Zuo, Meilu Yu, Hu Shunyin, Song Hong-qiang et autres

Cassandraに基づく大量MUSERデータ分散記憶と検索研究【JST・京大機械翻訳】

Shi Yue, Wang Feng, Li Pengcheng, Liu Yingbo

3陰性乳癌と免疫チェックポイント抑制療法の最新研究【JST・京大機械翻訳】

Xin-yuan Feng, Zhong Shaozheng, Shi Yue, Wang Haiyu et autres