Jianglong He

Investigating the anti-inflammatory potential of mulberry anthocyanins: Molecular docking, cellular studies, and zebrafish model verification

Yuqi Li, Jianglong He, Xueping JIANG, Haoran Huang et autres

Mulberry fruits contain a lot of anthocyanins, which are attributed to their medicinal characteristics. In this study, a combined method, which involves network pharmacology, molecular docking, molecular dynamics simulation and experimental validation, was used to test the anti-inflammatory activity of mulberry fruit …

cn (code pays fourni par la source)

Integrated Multi-Omics and Experimental Strategy Reveals the Anti-inflammatory Mechanism of Mulberry Seed Flavonoids: Implications for Functional Food

Haoran Huang, Jianglong He, Yuqi LI, Yue ZHANG et autres

cn (code pays fourni par la source)

Chloramphenicol biodegradation by Citrobacter freundii CT2: Degradation pathways, toxicity assessment, and genomic analysis

Xueping JIANG, Hao Li, Jia Kong, Yongjun Zang et autres

Chloramphenicol (CAP), a widely used antibiotic, persists in the environment and poses ecological risks. Despite the growing understanding of these degradation pathways of CAP, the secondary metabolic routes and their impacts on the environment remain poorly understood. Here, we aimed to characterize …

cn, kr (code pays fourni par la source)

Chloramphenicol Biodegradation by Citrobacter Freundii Ct2: Degradation Pathways, Toxicity Assessment, and Genomic Analysis

Xueping JIANG, Hao Li, Jia Kong, Yongjun Zang et autres

cn, kr (code pays fourni par la source)

Unravelling the Multi-target Anti-inflammatory Mechanisms of Mulberry Flavonoids: An Integrated Computational and Experimental Validation

Jianglong He, Yuqi Li, Yue Zhang, Xueping JIANG et autres

cn (code pays fourni par la source)

1-Deoxynojirimycin Derivative Containing Tegafur Induced HCT-116 Cell Apoptosis through Mitochondrial Dysfunction and Oxidative Stress Pathway

Liqin Tang, Yixing Xu, Jianglong He, Gaiqun Huang et autres

Three 1-deoxynojirimycin (DNJ) derivatives (named C4 – C6 ) including DNJ and tegafur (TGF) were designed and synthesized, and their antiproliferative effects were investigated. C4 – C6, especially C6, exerted good lipophilicity, α-glucosidase inhibitory activity, and antitumor effects. Mechanism studies indicated that …

cn (code pays fourni par la source)

MARS: optimistic therapy method in fulminant hepatic failure secondary to cytotoxic mushroom poisoning – a case report

Yufei Shi, Jianxing He, S Chen, Xi Yang et autres

BACKGROUND: Poisoning by cytotoxic mushrooms (Amanita phalloides and related species) is associated with severe morbidity and a high mortality rate (lethality > 20% in adults and > 50% in children). The main causes of this intoxication are the amatoxines, which inhibit DNA-dependent …

cn (code pays fourni par la source)