Meng Li

NQO1‑activated self‑reinforcing bimetallic nanoplatform triggers ferroptosis and cuproptosis for osteosarcoma therapy

Ye Zhang, Qingqing Bai, Yanhua Zhong, Xinjian Guo et autres

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A Self‐Augmenting Ion‐ROS Nanogenerator for Deep‐Penetration Pyroptosis‐Driven Immunotherapy of Solid Tumors

Yu Pang, Yuxin Wei, Xiaoyu Wang, Jie Lv et autres

ABSTRACT Pyroptosis holds significant potential for cancer immunotherapy by coupling tumor eradication with immune activation. However, its efficacy remains limited due to poor penetration of pyroptosis inducers and insufficient activation within tumors, primarily caused by dense extracellular matrix and elevated tumor interstitial …

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Silencing of optogenetic and chemogenetic transgenes in human iPSCs involves promoter methylation and methylation-independent mechanisms

Yiwen Wang, Yanyan Li, Jingzhen Li, Meng Li et autres

The transplantation of neural progenitor cells derived from induced pluripotent stem cells (iPSCs) has therapeutic potential for the treatment of neurological diseases. However, the functional integration of transplanted iPSC-derived neurons into host neural networks remains controversial. Optogenetic and chemogenetic tools offer the …

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Disease Severity Treatment Outcomes in Vitiligo: A Systematic Review of Randomized Controlled Trials

Jia Bai, Ryan S.Q. Geng, Meng Li, Edgar Akuffo‐Addo et autres

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Self-amplifying hypoxia cascade in covalent organic framework/metal organic framework nanoreactors for synergistic cancer therapy

Chengcai He, Xiaozhen Liu, Chi Yu, Jie Lv et autres

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Spatiotemporal heterogeneity of population exposure to outdoor days across China’s climatic zones

Kwan Hyung Yi, Haixia Lin, Tehseen Javed, Ning Yao et autres

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Establishment and application of a dual RPA-LFD rapid detection method for Salmonella Pullorum and Salmonella Enteritidis

Can Wang, Tingting Zeng, Houxun Ya, Li‐Jun Wan et autres

Salmonella species are known to cause a significant decline in poultry production performance and to contaminate various stages of the breeding process, with Salmonella Pullorum (S. Pullorum) and Salmonella Enteritidis (S. Enteritidis) being the predominant serotypes responsible for infection in poultry. For …

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A Study on the Use of Real Cases in Short Videos for Lung Cancer Public Awareness and Users' Willingness to Seek Relevant Health Information

Meng Li

This study aims to explore the impact of real case presentations in medical and health science popularization short videos on users' willingness to seek health information. With the popularity of social media, short videos have become a key channel for the public …

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Abstract 4372833: Study on the Mechanism of Protocatechualdehyde in Improving Sepsis-Induced Cardiomyopathy by Targeting Mitochondrial ROS and Inhibiting the GSDMD/STING Pathway in Macrophage

Meng Li, Yirong Wu, Yizhou Xu

Background: Sepsis-induced cardiomyopathy (SICM) is a major cause of high morbidity and mortality in septic patients. In SICM, macrophage infiltration and aberrant immune activation play a critical role in triggering inflammatory responses in cardiac tissue. Our previous studies identified that among 23 …

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Near Infrared‐Activatable Nanomodulator Enabling Self‐Amplifying Calcium Overload and Oxidative Stress for Precision Cancer Therapy

Chunzhe Xu, Xiaoyu Wang, Haozhe Zhang, Yanhua Zhong et autres

Abstract Calcium interference therapy (CIT) is a promising cancer therapeutic strategy, but its efficacy is limited by intrinsic cellular calcium regulation. To address this limitation, herein, a near‐infrared (NIR)‐responsive nanoplatform, UC@COFs@CaO 2 ‐HA/PAG/ICG (UCCPI), integrating dual‐amplified CIT with photodynamic therapy (PDT) is …

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Acupuncture promotes antidepressant effects by enhancing hippocampal neurogenesis via Wnt/β-catenin signaling in a chronic unpredictable mild stress-induced rat depression model

Zhuoran You, Meng Li, Jingyu Zeng, Jianguo Li et autres

BACKGROUND: Acupuncture is a common complementary treatment for anxiety and depression. This study aimed to investigate whether acupuncture at Shangxing (GV23) and Fengfu (GV16) alleviates chronic unpredictable mild stress (CUMS)-induced depressive-like behaviors in rats, and to explore the underlying mechanisms involving the …

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High-strength biodegradable Zn-0.6Cu-0.2Li-0.05Mg fine wires for intrauterine stents

Lei Zhang, Zhang‐Zhi Shi, Meng Li, Shenglian Yao et autres

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