Yaping Wang

Antibacterial Efficacy of Ethanol Extracts from Edible Rumex madaio Root and Application Potential for Eliminating Staphylococcus aureus and Vibrio cholerae in Aquatic Products for Green Food Preservation

Huanhuan Fan, Yue Liu, Yaping Wang, Shunlin Ren et autres

Edible and medicinal plants provide a treasure trove of natural phytochemicals for mining the next generation of green food preservatives. Herein, we evaluated antibacterial activities of 55–95% ethanol extracts from the edible rhizome of Rumex madaio (RmEEs). The 75% ethanol extract displayed …

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Activated PI3K-δ syndrome presenting with cervical lymphadenopathy in a pediatric patient: a case report and review of the literature

Zhiwei Huang, Yaping Wang, Hui Ding, Lian Du et autres

Background: Activated phosphoinositide 3-kinase delta syndrome (APDS) is a primary immunodeficiency caused by gain-of-function mutations in the PIK3CD gene, leading to dysregulated immune responses. Clinical manifestations include recurrent infections, lymphoproliferation, and increased risk of malignancies. Due to its rarity and variable presentation, …

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Interleukin-13 gene polymorphisms and asthma susceptibility in children: a meta-analysis

Song Su, Tong Zhang, Yaping Wang, Huan Zhang et autres

BACKGROUND: Interleukin (IL)-13 is a central mediator of airway inflammation in asthma, and gene polymorphisms may play a role in asthma pathogensis. However, the relationship between IL-13 gene polymorphisms and asthma susceptibility remain unclear. Therefore, we conducted this meta-analysis to evaluate this …

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Hypoxia combined with a high-fat diet aggravates pulmonary vascular endothelial dysfunction in rats

Yan-Xia Zhao, Lai-You Li, Hongyu Li, Xiaoqin Wu et autres

OBJECTIVES: Hypoxia and high-fat diet are independent risk factors for pulmonary vascular endothelial dysfunction (VED); however, their interactive effects are poorly understood. This study aimed to elucidate the effect and mechanism of hypoxia combined with a high-fat diet on the pulmonary arterial …

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Tannic acid-iron stabilized probiotic silver nano hybrids: Multi-target gut microbiota modulation and intestinal barrier restoration

Saisai Gong, Zhibo Zeng, Chuxian Quan, M Rahim et autres

The limited efficacy and adverse effect profile of current pharmacological treatments for intestinal inflammation underscore the need for modalities that preserve gut microbiota balance while attenuating inflammation. The aim of this study was to develop and evaluate a BL@TA-Fe III @AgNPs system …

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Elucidation of antibacterial efficacy and mechanism of the extract from fruit of Phyllanthus emblica L. against Vibrio cholerae and Staphylococcus aureus

Fengfeng Cao, Yue Liu, Yaping Wang, Shunlin Ren et autres

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Assembly of T4 bacteriophages with β-galactosidase for electrochemical detection of Escherichia coli K12

Qiaoli Yang, Yaping Wang

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Discovery of a novel regulator, 3β-sulfate-5-cholestenoic acid, of lipid metabolism and inflammation

Yaping Wang, Arun Jayant Sanyal, Phillip B. Hylemon, Shunlin Ren

This study identifies a novel oxysterol metabolite, 3β-sulfate-5-cholestenoic acid (3SCA), secreted by hepatocytes, which regulates lipid metabolism and inflammatory responses in hepatocytes and macrophages. These findings reveal previously unknown metabolic pathways of mitochondrial oxysterols and their roles in the progression and recovery …

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Assembly of T4 Bacteriophages with Β-Galactosidase for Electrochemical Detection of Escherichia Coli K12

Qiaoli Yang, Yaping Wang

Epileptic seizures as an initial symptom for Sturge‑Weber syndrome type III: A report of two cases

Yaping Wang, Guifu Geng, Wandong Hu, Huan Zhang et autres

Sturge-Weber syndrome (SWS) type III, a rare neurocutaneous disorder, presents diagnostic challenges due to its variable clinical manifestations. The present study focuses on enhancing the understanding of this syndrome by conducting a detailed analysis of two pediatric cases and providing a comprehensive …

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Microglial exosomes in paraquat-induced Parkinson's disease: Neuroprotection and biomarker clues

Jingwen Wu, Wenya Shao, Xu Liu, Fuli Zheng et autres

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Cardiac injury progression in children with multisystem inflammatory syndrome associated with SARS-CoV-2 infection: a review

Song Su, Wandong Hu, Xiao Chen, Ying Ren et autres

The symptoms and signs of infection caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are milder in children than in adults. However, in April 2020, British pediatricians first reported that coronavirus disease 2019 (COVID-19) may present as multisystem inflammatory syndrome in …

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