Ke Chen

Immune Escape in Renal Cell Carcinoma: Latest Research and Treatment Strategies

Kaixiang Huang, Ke Chen

Renal cancer is a common malignant tumor in the urinary system. Current research has found that immune escape in kidney cancer can prevent immune system attacks through specific mechanisms, making it difficult for the immune system to effectively kill cancer cells, and …

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Realization of the Value of Ecological Products in National Parks: Basic Logic, Core Mechanisms and Modes

Jin Xue, Lu Jie, Ke Chen

The construction of national parks is a strategic choice for safeguarding national ecological security and an urgent need for increasing the supply of high-quality ecological products. To sort out the basic logic and internal connections of the value realization of ecological products …

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An integrative framework combining Mendelian randomization, single-cell profiling, and experimental validation identifies FTMT as a mitochondrial–immune regulator in non-small cell lung cancer

Shouyong Xiao, Siyun Wu, Xianfeng Shao, Ming Wei Chao et autres

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Chinese Yi Lacquerware—Inheritance and Innovation

Wang Feng, Ke Chen

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Association between early life famine exposure and T2D among Chinese immigrants: a population-based cohort study

Aili Cao, Zhen Hong, Ning Liu, David M. Lee et autres

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Effectiveness of digital interventions in middle-aged and older adults with mild cognitive impairment: A systematic review and meta-analysis of randomized controlled trials

Ke Chen, Yun Yue, Yu Zhang, X. H. Wu et autres

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Next-generation enhancer AAVs for selective interspecies targeting of midbrain dopaminergic neurons

Kian A. Caplan, Ke Chen, Ricardo C.H. del Rosario, Fenna M. Krienen et autres

Abstract Using single-nucleus multiomic profiling of the marmoset midbrain, we develop and benchmark enhancer–AAVs to selectively access dopamine (DA) neurons in wild-type animals without combinatorial systems. In vivo candidate screenings identified one highly specific DA enhancer, cjDAE8, in both mice and marmosets. …

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Efficacy of Hypofractionated Stereotactic Radiotherapy with Different Dose Fractionation Regimens Combined with Concurrent Bevacizumab in Recurrent High-Grade Gliomas: A Randomized Controlled Trial

Feng Liu, Hui Wang, Xin Chen, Wei Zhu et autres

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A Galactose‐Engineered Dual‐Responsive Nanocarrier for ASO/CRISPR‐Cas9 Delivery to Inhibit HBV Replication

Liuxian Chen, Qin Huang, Yongjie Liu, Ke Chen et autres

Complete hepatitis B virus (HBV) cure is hindered primarily by the stable persistence of covalently closed circular DNA (cccDNA). Gene editing approaches to eradicate HBV by targeting cccDNA face challenges and limitations due to suboptimal editing efficiency and substantial off-target effects. Herein, …

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EP.08.38 Real-World Data of Adjuvant Therapy With Aumolertinib for EGFR-Mutated NSCLC Patients

Huan Liu, Liping Tong, Hubin Duan, Xiaoyu Dong et autres

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P2.08.43 Perioperative Adebrelimab Plus Chemotherapy in Patients With Resectable Stage II-III NSCLC: 4-Year Update From a Phase 1b/3 Trial

Yi-Long Lung Cancer Wu, Wenqing Yan, W-Z. Zhong, Yunhui Liu et autres

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Surface Temperature Assisted State of Charge Estimation for Retired Power Batteries

Lei Xu, Wenxuan Han, Jiawei Dong, Ke Chen et autres

Accurate State of Charge (SOC) estimation for retired power batteries remains a critical challenge due to their degraded electrochemical properties and heterogeneous aging mechanisms. Traditional methods relying solely on electrical parameters (e.g., voltage and current) exhibit significant errors, as aged batteries experience …

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