Dandan Li

Efficacy and Safety of Co‐Ablation Combined With Aintilimab for Metastatic Melanoma to the Liver (CryoCheck‐001): A Phase II Trial

Lujun Shen, Letao Lin, Shuanggang Chen, Chen Li et autres

Liver metastasis is a key driver of immune tolerance in melanoma, limiting immune checkpoint inhibitor efficacy. This prospective single-arm phase II trial investigated the efficacy and safety of co-ablation combined with sintilimab for liver-metastatic melanoma (ChiCTR2200061591). Eligible patients received sintilimab (anti-PD-1, 200 …

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Copper isotope perspective on sulfide-silicate liquid immiscibility

Li-Juan Zhu, Lie-Meng Chen, Peter C. Lightfoot, Sheng-Ao Liu et autres

cn, ca (code pays fourni par la source)

[Expression of GATA3 in Patients with Peripheral T-Cell Lymphoma and Its Clinical Significance].

Wen-Juan Li, Xue Guo, Xin Cheng, Feng-jiao Yue et autres

OBJECTIVE: To investigate the expression of the GATA binding protein 3 (GATA3) gene in patients with peripheral T-cell lymphoma (PTCL) and its clinical significance. METHODS: gene in their tissue samples was detected, and efficacy evaluation and survival analysis were performed for the …

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Isolation and whole-genome characterization of an emerging G9P[23] porcine rotavirus in Central China

Chaoliang Leng, Jiabao Wang, Jiajia Cao, Tianyu Jia et autres

Rotavirus (RV), a significant enteric pathogen, causes diarrheal disease in both nursing piglets and infants. To characterize the genomic features and evolutionary patterns of a porcine rotavirus (PoRV) strain, we isolated viral strains from RT-qPCR confirmed PoRV-positive diarrheic piglet specimens through MA104 …

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Electrochemically Driven Direct Participation of Chalcogenophenols in 1,2-Thio/Seleno-Heteroarylation of Alkenes

Siyu Wang, Tingting Cai, Dandan Li, Bowen Xu et autres

Herein, we report an electrochemically driven three-component strategy that successfully achieves direct coupling of nonpreactivated chalcogenophenols with styrenes and N-heteroarenes, enabling efficient construction of the biologically significant β-azaaryl chalcogenoether. The key to this strategy lies in an anodic oxidation-mediated deprotonation-oxidation pathway, which …

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A multi-axis spatiotemporal attention model with multilayer convolution and Kolmogorov-Arnold Networks for ENSO prediction

Bin Wang, Minxin Jing, Dandan Li, Xiao Dong et autres

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A novel homozygous KEL variant causing K 0 phenotype in a Chinese woman and therapeutic plasma exchange for anti‐Ku removal in preoperative management

Danxin Du, Dong Xiang, Xinfang Zhu, Aijing Li et autres

BACKGROUND: are often identified after developing anti-Ku, an antibody associated with hemolytic transfusion reactions (HTR) and hemolytic disease of the fetus and newborn (HDFN). Transfusion management in this population is particularly challenging as compatible blood is difficult to find. It is crucial …

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Intelligent Prediction of Surface Turbulent Fluxes: An Innovative Approach Based on the iTransformer Model

Dandan Li, Minxin Jing, Xuan Lei, Bin Wang et autres

Abstract Surface turbulent fluxes constitute key energy exchanges in the atmospheric boundary layer (ABL). Accurate prediction of variations in the ABL is essential for agricultural ecology and climate studies. Existing prediction methods include those based on Monin–Obukhov similarity theory (MOST) and machine …

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SLC22A3 Regulates Ferroptosis in the Mesenchymal Subtype of Triple-Negative Breast Cancer by Modulating Histone H3K4 Serotonylation

Zifan Lu, Dongsheng Zhai, Li Wang, Guo Chen et autres

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Comparison of the efficacy of aerosolized inhalation of different doses of recombinant human interferon alpha1b combined with budesonide in the treatment of asthmatic bronchitis in children

Long yu Huang, Qin Zhang, Yong Chen, Kangkang Li et autres

Background: Asthmatic Bronchitis (AB) is the most common type of bronchitis in children, severely affecting their quality of life and growth. This study aimed to investigate the efficacy and safety of aerosol inhalation of different doses of Recombinant Human Interferon alpha1b (IFNα1b) …

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MA11.03 Tifcemalimab Plus Toripalimab and Chemotherapy as a First-Line Therapy in ES-SCLC: A Phase Ib/II Study

Yao Yu, Chen Ya, Ying Zhang, Wendong Zhang et autres

cn, mn, us (code pays fourni par la source)

Serum metabolic changes in acute myelogenous leukemia during initial chemotherapy and their prognostic implications

Rong Hu, Dandan Li, Xiaofan Jia, Yating Zhang et autres

Motivation: Acute myeloid leukemia is marked by complex metabolic adaptations. Identifying metabolic alterations in patients may provide insights into treatment responses. Goal(s): The study aims to explore serum metabolic profiles of newly diagnosed AML patients throughout their initial chemotherapy stages to find …