Lei Zhang

Plasma Bile Acids Profiling Identifies Chenodeoxycholic Acid as a Marker to Differentiate Impaired Glucose Tolerance Patients from Healthy Individuals

Lei Zhang, Xu Liu, Tenghui Jin, Jing Dong et autres

cn (code pays fourni par la source)

Geniposide inhibits cell proliferation and migration in human oral squamous carcinoma cells via AMPK and JNK signaling pathways

Guohui Bai, Bin Chen, Xin Xiao, Yuexin Li et autres

Iridoids are a special class of cyclopentanoid monoterpenes, which exhibit a wide range of biological effects. The present study aimed to investigate the potential effects of three iridoids genipin, geniposide and geniposidic acid on three human oral squamous cell carcinoma (OSCC) cell …

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Chemotherapy-induced peripheral neuropathy is promoted by enhanced spinal insulin-like growth factor-1 levels via astrocyte-dependent mechanisms

Yue Le, Xin Chen, Long Wang, Wanyou He et autres

cn (code pays fourni par la source)

Malyngamide F Possesses Anti-Inflammatory and Antinociceptive Activity in Rat Models of Inflammation

LI Zhuo-cheng, Lei Zhang, Zhichao Zhao

Objective. Inflammation and pain are involved in the pathophysiology of various clinical conditions. This investigation aims to probe the analgesic and anti-inflammatory activity of Maltoamide F. Methods. The possible toxicity of Maltoamide F was evaluated by an acute toxicity test. To assess …

cn (code pays fourni par la source)

Spice up your food for cancer prevention: Cancer chemo-prevention by natural compounds from common dietary spices

Jie Gao, Kenza Mamouni, Lei Zhang, Bal L. Lokeshwar

us (code pays fourni par la source)

Dipeptidyl peptidase-4 promotes calcification of human vascular smooth muscle cells through ERK1/2 signaling pathway

Weidan Luo, Xueqin Wang, Huqiang He, Lei Zhang et autres

Objective To further investigate direct effects of dipeptidyl peptidase-4(DPP4)on calcification and to identify responsible signaling pathways in human vascular smooth muscle cells(HVSMC). Methods The effect of DPP-4 on calcification of HVSMC was observed by alizarin red, and Western blot was used to …

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Genipin Derivatives Protect RGC-5 from Sodium Nitroprusside-Induced Nitrosative Stress

Rikang Wang, Jiaqiang Zhao, Lei Zhang, Lizhi Peng et autres

CHR20 and CHR21 are a pair of stable diastereoisomers derived from genipin. These stereoisomers are activators of neuronal nitric oxide synthase (nNOS) and endothelial nitric oxide synthase (eNOS). In the rat retinal ganglion (RGC-5) cell model these compounds are non-toxic. Treatment of …

cn, mo (code pays fourni par la source)

Quitline Use and Effectiveness Among Young Adults

Lei Zhang