Zhihua Liu

Pretreatment viral quasispecies characteristics and evolutionary phases correlate with HBsAg seroconversion in peginterferon-alfa-2a-treated children with HBeAg-positive chronic hepatitis B

Juncheng Yang, Guifeng Yang, Haitang He, Hai Liu et autres

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Interacting and joint effects of type of menopause and age at menopause on the likelihood of frailty and the mediating role of age at menopause in older women: A population-based analysis from NHANES 1999–2018

Huijie Guo, Yilu Ye, Zhihua Liu, Yunfei Gao et autres

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Baveno VI-SSM stratifies the risk of portal hypertension-related events in patients with HBV-related cirrhosis

Weihao Liang, Ling Zhou, Jiankang Song, Biao Wen et autres

BACKGROUND/AIMS: Cirrhotic patients with liver stiffness measurement (LSM) <20 kPa and platelet count ≥150×109/L (Baveno VI criteria), otherwise spleen stiffness measurement (SSM) ≤40 kPa (Baveno VI-SSM criteria) can avoid endoscopy screening; however, no prospective data for their hepatic outcomes. METHODS: Compensated cirrhosis …

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List of contributors

Muhammad Radzi Abu Hassan, Oidov Baatarkhuu, Ajeet Singh Bhadoria, David Charles Boettiger et autres

Detection of CRISPR‒Cas and type I R–M systems in Klebsiella pneumoniae of human and animal origins and their relationship to antibiotic resistance and virulence

Xue Li, Ling Wang, Yingjuan Gu, Zhihua Liu et autres

ABSTRACT The clustered regularly interspaced short palindromic repeats (CRISPR)‒CRISPR-associated protein (Cas) and restriction‒modification (R–M) systems are important immune systems in bacteria. Information about the distributions of these two systems in Klebsiella pneumoniae from different hosts and their mutual effect on antibiotic resistance …

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Distinct Binding Modes of Inter-Spike Cross-Linking Suggest a Supplementary Mechanism for SARS-CoV-2 Antibody Neutralization

Xuanyu Nan, Yujie Li, Rui Zhang, Ruoke Wang et autres

Abstract The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its Omicron subvariants drastically amplifies transmissibility, infectivity, and immune escape, mainly due to their resistance to most neutralizing antibodies. Thus, exploring the mechanisms underlying antibody evasion is crucial. Although the …

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Squamous cell lung cancer coexisting with pulmonary MALT lymphoma: a rare case report

Ao Li, Lei Jiang, Yu‐Wen Hu, Zhihua Liu et autres

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The intake of solid fat and cheese may be associated with a reduced risk of Helicobacter pylori infection status: a cross-sectional study based on NHANES 1999–2000

Huan Zhang, Chao Xu, J. Zhang, Jumei Yin et autres

BACKGROUND: Diet plays an important role in Helicobacter pylori (HP) infection, and our objective was to investigate potential connections between dietary patterns, specific food groups, and HP infection status in U.S. adults. METHODS: The data for this study was obtained from the …

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Mortality associated with carbapenem resistance in Klebsiella pneumoniae bloodstream infection: A propensity score–matched study

Ling Wang, Chaoying Zeng, Xue Li, Yuqing Li et autres

Abstract Objective: Klebsiella pneumoniae are common pathogens causing bloodstream infection (BSI) that increasingly express carbapenem resistance worldwide. To date, no study has precisely investigated the impact of carbapenem resistance in K. pneumoniae (CRKP) BSI on mortality. Methods: This retrospective study included 87 …

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Real-world implementation of a multilevel interventions program to prevent mother-to-child transmission of HBV in China

Xueru Yin, Wei Qiang Wang, Hui Chen, Qing Mao et autres

Reducing hepatitis B virus (HBV) mother-to-child transmission (MTCT) is a fundamental step toward the HBV elimination goal. The multicentred, multilevel SHIELD program aimed to use an intense intervention package to reduce HBV MTCT in China. This study was conducted in diverse health …

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Age at first birth is associated with the likelihood of frailty in middle-aged and older women: A population-based analysis from NHANES 1999–2018

Huijie Guo, Yilu Ye, Yunfei Gao, Zhihua Liu

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Association between the cumulative dose of glucocorticoids before the development of pneumonia and death in patients receiving long-term glucocorticoids: a secondary analysis based on a Chinese cohort study

Huijie Guo, Yilu Ye, Rong Cao, Zhihua Liu et autres

Background: The present study aimed to evaluate the association between the cumulative dose of glucocorticoids (GCs) and case fatality in hospitalized patients who developed pneumonia while receiving glucocorticoid therapy. Methods: This retrospective cohort study included 625 patients receiving long-term GC treatment who …

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