Yuliang Wang

Screening of dsRNA targets in the salivary glands of M yzus persicae and development of a T richoderma ‐based bio‐expression system

Yuxin Hou, Xinhua Wang, Jie Chen, Yiyang Han et autres

BACKGROUND: Aphids are globally prevalent pests that inflict considerable harm on plants. Owing to increasing pesticide resistance, it is crucial to develop environmentally sustainable and effective control methods. RNA interference (RNAi) using double-stranded RNA (dsRNA) holds great promise for pest control, but …

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Structural Characterization of a Novel Galactoarabinan from Baphicacanthus cusia and Its Protective Effects Against Oxidative Stress and Inflammation via the PI3K/Akt and Nrf2/HO-1 Signaling Axes

Z Zuo, Chen Yang, Wenli Liang, Qian Zhang et autres

The roots of Baphicacanthus cusia (Nees) Bremek, commonly known as Nan-Ban-Lan-Gen, have been used for a long time in traditional Chinese medicine to manage inflammatory and infectious diseases. However, the structural features and bioactive potential of its polysaccharides have not been extensively …

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[Pathogenesis of "inflammation cancer transformation" in chronic atrophic gastritis and TCM entropy-reducing prevention and treatment strategies based on entropy disease theory].

Song Zhi-xin, Xiao-Na Sun, Bin Sun, Meng-Ke An et autres

Gastric cancer(GC) is the fifth most common malignancy worldwide and the third leading cause of cancer-related deaths. Chronic atrophic gastritis(CAG) is the most common precursor lesion of GC, and its "inflammation cancer transformation" is a multi-step, multifactorial process. Based on the second …

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Specialized structures and developmental mechanisms of secondary metabolite‐synthesizing organs and tissues in medicinal plants

Xueqing Fu, Yaojie Zhang, Muyao Yu, Han Zheng et autres

Specialized structures in medicinal plants underpin the spatial regulation of secondary metabolism, determining the biosynthesis, accumulation, and storage of pharmacologically active compounds. Specialized structures, such as glandular trichomes, roots, rhizomes, laticifer, heartwood, and so on, have evolved distinct developmental programs and metabolic …

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Identification and validation of biomarkers related to centrosome replication in ulcerative colitis based on bulk transcriptome, single-cell RNA sequencing and experiments

Zhenhuan Yang, Xingxing Wu, Lei Luo, Xiuxia Wu et autres

Background: Ulcerative colitis (UC) is a complex chronic inflammatory disease. Centrosome amplification (CA) has been implicated in UC pathogenesis, but its mechanistic role remains unclear. This study aimed to investigate the relevance of centrosome amplification-related genes (CARGs) in UC progression. Methods: UC …

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Magnesium Plus Hydrogen Fertilization Enhances Mg Uptake, Growth Performance and Monoterpenoid Indole Alkaloid Biosynthesis in Catharanthus roseus

Chaoqin Ou, Xinmin Qiu, Qian Zhao, Ding Ding et autres

Magnesium and hydrogen fertilization have been reported to contribute to plant growth and metabolite production. Simultaneous fertilization of magnesium and hydrogen is a promising strategy for plant development and secondary metabolism, but remains unexplored in Catharanthus roseus (L.) G.Don, which produces varieties …

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Jasmonate‐Activated AaWRKY9 – AabHLH93 / AabHLH93 – AaMYB7 Complexes Balance Artemisinin Biosynthesis in Artemisia annua

Xueqing Fu, Han Zheng, Yaojie Zhang, Ming Zien Yu et autres

Artemisinin, an antimalarial sesquiterpene lactone, is biosynthesized in glandular trichomes of Artemisia annua. Although numerous transcription factors have been demonstrated to regulate artemisinin biosynthesis, the molecular mechanisms underlying the high expression of artemisinin-associated biosynthetic enzyme and transcription factor genes in young leaves …

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Liraglutide alleviates sepsis-induced encephalopathy via attenuating neuronal damage, glial cell activation and mitochondrial dysfunction in a mouse model of sepsis

Hongyu Yi, Yan Jiao, Hui He, Linjue Wang et autres

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Evaluating Non-Invasive Biomarkers and Composite Scores for Liver Fibrosis Diagnosis in Hepatitis B and C Infections

Tamer A. Addissouky, Ibrahim El Tantawy El Sayed, Ayman E. El Agroudy, Yuliang Wang

us, Égypte, cn (code pays fourni par la source)

Assembly and characterization of the first mitochondrial genome of Phyllanthaceae: a case study of the ornamental aquatic plant Phyllanthus fluitans

Yuliang Wang, Qiang Li, Xing Jian

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Online takeaway food consumption and its association with health among young and middle-aged urban residents in mainland China: a cross-sectional study

Ke Jin, Tianyuan Pan, Tao Zeng, Yuliang Wang et autres

BACKGROUND: Although ordering food online has become a leading lifestyle factor among the Chinese urban population, its health impact is understudied. This study aims to examine this aspect, focusing on online takeaway food impacts related to foodborne illness, nutrition, and suboptimal health …

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Comprehensive analysis of SPL gene family and miR156a/SPLs in the regulation of terpenoid indole alkaloid biosynthesis in Catharanthus roseus L

Yaojie Zhang, Xianjun Ni, Xueqing Fu, Ayat Taheri et autres

BACKGROUND: Catharanthus roseus (C. roseus), belongs to the dogbane family Apocynaceae, is the source of various terpenoid indole alkaloids (TIAs) with excellent antitumor properties, including vinblastine, vincristine, ajmalicine, serpentine, vindoline, and catharanthine. However, TIAs are widely used in clinical anticancer research, their …

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