Bin Zhang

Transperitoneal vs retroperitoneal laparoscopic radical nephrectomy: a double-arm, parallel-group randomized clinical trial

Junyao Liu, Bin Zhang, Peng Qi, Xiaowei Ren et autres

OBJECTIVE: To compare the outcomes of patients undergoing Retroperitoneal laparoscopic Radical nephrectomy (RLRN) and Transperitoneal laparoscopic Radical nephrectomy (TLRN). METHODS: A total of 120 patients with localized renal cell carcinoma were randomized into either RLRN or TLRN group. Mainly by comparing the …

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Establishment and validation of a prognostic nomogram for patients with renal cell carcinoma based on SEER and TCGA database

Changming Wang, Baorui Wu, Deyun Shen, Bin Zhang et autres

Background: Renal cell carcinoma (RCC) is a lethal urological malignancy. Precise risk-stratification is very important for decision-making in postoperative patient management. This study aimed to establish and validate a prognostic nomogram of overall survival (OS) in patients with RCC based on Surveillance, …

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Retroperitoneal laparoscopic radical nephrectomy (RLRN) is associated with poor integrity of Gerota's fascia and perirenal fat: A prospective comparative study

Junyao Liu, Duo Zheng, Peng Qi, Zheng Xu et autres

Purpose To figure out the difference of integrity of Gerota's fascia and perirenal fat between Retroperitoneal Laparoscopic Radical Nephrectomy (RLRN) and Transperitoneal Laparoscopic Radical Nephrectomy (TLRN). Methods This is a prospective comparative study of patients with Renal Cell Carcinoma (RCC) from a …

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TAGLN2 Promotes the Proliferation, Migration, Invasion, and EMT of Clear Cell Renal Cell Carcinoma Through the PI3K/Akt Signaling Pathway

Yang He, Bin Zhang, Dali Han, Yuelin Du et autres

The effect of Transgelin 2 (TAGLN2) on clear cell renal cell carcinoma (ccRCC) is unknown. This study explored the potential role and mechanism of ccRCC. The expression of TAGLN2 in Pan-cancers was analyzed using the Genotype-Tissue Expression (GTEx) and The Cancer Genome …

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The RBPJ/DAPK3/UBE3A signaling axis induces PBRM1 degradation to modulate the sensitivity of renal cell carcinoma to CDK4/6 inhibitors

Wentao Liu, Bin Zhang, Dan Zhang, Feng Guo et autres

Renal cell carcinoma (RCC) is a kind of malignant tumor originating from the renal tubular epithelium. Approximately 30% of patients with renal cancer are found to have metastasis when first diagnosed. Exploring other effective treatment methods in addition to surgery is an …

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Synchronous sporadic bilateral multiple chromophobe renal cell carcinoma accompanied by a clear cell carcinoma and a cyst: A case report

Fan Yang, Zichen Zhao, Ajin Hu, Pengfei Sun et autres

BACKGROUND: Renal cell carcinomas are usually unilateral. However, they are bilateral in 2% to 4% of sporadic cases and is considerably more common in familial cases. Synchronous sporadic bilateral multiple chromophobe renal cell carcinoma (CHRCC) with different subtypes is rare. CASE SUMMARY: …

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FLCN-regulated miRNAs suppressed reparative response in cells and pulmonary lesions of Birt-Hogg-Dubé syndrome

Haiyan Min, Dehua Ma, Wei Zou, Yongzheng Wu et autres

BACKGROUND: Birt-Hogg-Dubé Syndrome (BHDS) characterised by skin fibrofolliculomas, kidney tumour and pulmonary cysts/pneumothorax is caused by folliculin (FLCN) germline mutations. The pathology of both neoplasia and focused tissue loss of BHDS strongly features tissue-specific behaviour of the gene. Isolated cysts/pneumothorax is the …

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Retrospective analysis on the efficacy of sunitinib/sorafenib in combination with dendritic cells-cytokine-induced killer in metastasis renal cell carcinoma after radical nephrectomy

Haixing Mai, Mei Guo-Hui, Feilong Zhao, Botao Li et autres

OBJECTIVE: Sunitinib/sorafenib (SU/SO), dendritic cells (DCs), or DC-cytokine-induced killer (CIK) could significantly prolong progression-free survival (PFS), 3-year overall survival (OS), or 5-year OS for patients with metastatic renal cell carcinoma (mRCC). We retrospectively analyzed the clinical efficacy between SU/SO combined with DC-CIK …

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A follow-up analysis of positron emission tomography/computed tomography in detecting hidden malignancies at the time of diagnosis of membranous nephropathy

Zhonglin Feng, Shu-Xia Wang, Yanlin Huang, Xinling Liang et autres

// Zhonglin Feng 1 , Shuxia Wang 2 , Yanlin Huang 3 , Xinling Liang 1 , Wei Shi 1 and Bin Zhang 1 1 Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China 2 Department of Nuclear …

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Preoperative planning and real-time assisted navigation by three-dimensional individual digital model in partial nephrectomy with three-dimensional laparoscopic system

Dongwen Wang, Bin Zhang, Xiaobin Yuan, Xuhui Zhang et autres

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[Application of internal mammary artery perforator flap for tracheostoma and anterior cervical defect].

Bin Zhang, Dangui Yan, Yun Feng, Zhen-gang Xu et autres

UNLABELLED: OBJECTIVE To investigate the application of pedicled internal mammary artery perforator (IMAP) flap for tracheostoma and anterior cervical defect. METHODS: From April to December 2009, 4 IMAP flaps, based on the second internal mammary artery perforator, were used for two cases …

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Effect of Haishengsu as an Adjunct Therapy for Patients with Advanced Renal Cell Cancer: A Randomized and Placebo-Controlled Clinical Trial

Jizhu Liu, Shou-Guo Chen, Bin Zhang, Chunbo Wang et autres

OBJECTIVE: The purpose of this study was to investigate the effect of Haishengsu, an extract from Tegillarca L. granosa, on the effects and side-effects of immunotherapy in patients with advanced renal cell cancer. METHODS: Fifty-five (55) patients with renal cell cancer were …

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