Jaehun Lee

Telomerase reverse transcriptase (TERT) accelerates β-catenin-driven hepatocarcinogenesis via MAPK/ERK pathway activation

Hyunjung Park, Jaehun Lee, Hyuk Moon, Simon Weonsang Ro

Mutations in CTNNB1 and in the TERT promoter are among the most prevalent genetic alterations in hepatocellular carcinoma (HCC), yet their functional cooperation in hepatocarcinogenesis remains poorly defined. This study aimed to elucidate the molecular interplay between β-catenin and TERT in driving …

kr (code pays fourni par la source)

First-in-Human Imaging Results of PHAROS: A Versatile High-Resolution TOF/DOI PET Scanner for Brain, Breast, and Extremity Imaging

Guen Bae Ko, Kyeong Yun Kim, Seung Kwan Kang, Jaehun Lee et autres

We present the design and performance of the newly developed PHAROS—a high-resolution, multifunctional PET system integrating time-of-flight (TOF) and depth-of-interaction (DOI) technologies—and report its first-in-human imaging results for brain and breast applications in multiple patient positions. Methods: The PHAROS system features a …

kr, pr, Éthiopie (code pays fourni par la source)

Characterization and mechanistic regulation of the Bovine inflammasome

Huijeong Ahn, Jaehun Lee, Gilyoung Lee, Younghye Ro et autres

kr, jp (code pays fourni par la source)

마취 후 회복실에서의 구조 항구토제 투여 예측을 위한 머신러닝 모델의 개발 및 외부 검증

Jaehun Lee

학위논문(석사) -- 서울대학교 대학원 : 의과대학 의학과, 2026. 2. 이형철.

'이미지론'을 통해 본 관료제와 외교정책 결정구조를 중심으로

Jaehun Lee

학위논문(석사) -- 서울대학교 대학원 : 행정대학원 행정학과(정책학전공), 2026. 2. 구민교.

Epithelial WNT secretion drives niche escape of developing gastric cancer

Jaehun Lee, Soomin Kim, Youngchul Oh, Stephan R. Jahn et autres

BACKGROUND: WNT signaling plays a key role in maintaining the gastric epithelium and promoting tumorigenesis. However, how gastric tumors achieve WNT niche independence remains unclear, as mutations on APC or CTNNB1-common mechanisms of ligand-independent WNT activation in colorectal cancer-are infrequent in gastric …

kr, de, at, mx, us (code pays fourni par la source)

An Examination of Reporting and Recording Practices in Construction Safety Management: Analyzing Improvements under the Construction Technology Promotion Act

Jaehun Lee, M Park, 안창범

건설산업에서 발생하는 사고의 빈도와 심각성이 증가함에 따라, 건설현장 안전관리의 중요성이 그 어느 때보다 강조되고 있다. 이와 같은 현행 건설산업 안전관리 관행의 문제점으로 건설현장의 과도한 서류작업이 지적되고 있다. 현장의 과도한 서류작업으로 인해, 안전관리 업무를 수행해야 할 안전관리자들이 본연의 업무를 등한시한 채 서류작업에 전념하고 …

Kinase suppressor of Ras 1 (KSR1) promotes liver carcinogenesis via activation of the RAS/RAF/MEK/ERK signaling pathway

Hyuk Moon, S.-H. Lee, Soyun Lee, Mihyeon Jun et autres

BACKGROUND & AIMS Mutations in the RAS and RAF genes are frequently observed in various human cancers, leading to persistent activation of the RAS/RAF/MEK/ERK signaling pathway and driving tumorigenesis. Intriguingly, hepatocellular carcinoma (HCC) reveals rare mutations in RAS and RAF , despite …

kr (code pays fourni par la source)

Mechanism of Annealing of Complementary DNA Strands by the Single-Stranded DNA Binding Protein of Bacteriophage T7

Seung‐Joo Lee, Sebastian Urbano, Jaehun Lee, Meghana Cheela et autres

Gp2.5, an essential single-stranded DNA-binding protein encoded by bacteriophage T7, is integral to various steps of DNA metabolism. Unlike other single-stranded DNA binding proteins, it greatly facilitates the annealing of complementary DNA strands. Gp2.5 efficiently anneals DNA duplexes as short as 30 …

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알류미늄 도핑된 하프늄옥사이드 박막과 비정질 인듐-갈륨-아연 산화물을 이용한 강유전 박막 트랜지스터의 메모리 윈도우 향상에 관한 연구

Jaehun Lee

학위논문(박사) -- 서울대학교 대학원 : 공과대학 재료공학부(하이브리드재료전공), 2025. 2. 황철성.

Unilateral Vestibulopathy Mimicking Inner Ear Ischemia Modeling Using Photothrombosis and Behavioral Assessment Using EthoVision

Minseok Song, Min Young Lee, Ji Eun Choi, So‐Young Chang et autres

Objectives: Inner ear ischemic animal models using photochemical reactions have been devised in various ways. Localized vascular ischemia occurs with 532-nm laser irradiation after systemic rose bengal injection, a known photothrombotic mechanism. The aim of this study is to evaluate a photothrombosis-induced …

Limitations in Transitioning from Conventional to Modern Total Knee Arthroplasty: A Review

Muhammad Sohail, Jaehyun Park, Jaehun Lee, Heung Soo Kim

kr (code pays fourni par la source)