Yi Zhang

Within-host evolution of tandemly duplicated blaKPC-14 conferring cross-resistance to ceftazidime-avibactam, cefiderocol and aztreonam-avibactam in hypervirulent ST11 Klebsiella pneumoniae

Fuyao Hu, Yi Zhang, Mingju Hao, Wenhua Li

Objectives Hypervirulent carbapenem-resistant Klebsiella pneumoniae (hv-CRKP) exhibiting cross-resistance to multiple antimicrobial agents represents a formidable therapeutic challenge. Therefore, elucidating the mechanisms driving antimicrobial resistance is crucial. Methods A ceftazidime-avibactam-resistant K. pneumoniae isolate was recovered and subjected to antimicrobial susceptibility testing and whole-genome …

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From Recycled Aluminum to Automotive Material: A Through‐Process Adjustment Strategy for Mitigating the Negative Impacts of Fe‐Contained Intermetallic Compounds

Jiale Ma, Yi Zhang, Dan Zhou, Sijia Mu et autres

ABSTRACT Increasing the usage of recycled aluminum (Al) is an efficient way to maintain a low‐carbon supply‐chain for modern automobile companies, where the major challenge is the mitigation of the negative effect of tramp element, such as Fe. This paper aims at …

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Design of integrated testing platform for ship platform monitoring system based on scene driven

Long Fan, Canzhi Gui, Yi Zhang, Xiaonan Song

The ship platform monitoring system provides real-time monitoring, control, and management of major systems (equipment) such as ship power, electricity, auxiliary pipeline networks, and ship installations based on typical mission requirements, and is an important force in ship typical mission support. As …

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Double-layer NiCo heterostructure and enzyme-free dual-circle DNA signal amplification for simultaneous detection of dual target microRNAs of lung cancer using microfluidic electrochemical sensor

Qingteng Lai, Yinghui Zhao, Yaqi Dong, Rongzhen Liu et autres

Detection of microRNAs (miRNAs) reveals tumor information at the transcriptional level, which is crucial for early diagnosis and prognosis of tumors. However, the rapid detection of miRNAs in biological samples without relying on large equipment remains a significant challenge. In this work, …

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A high-precision joint prediction method for robotic machining error decomposition embedded with error decomposition

Zaiming Geng, Yi Zhang, Hui Liu, Jing Yan et autres

Industrial robots have become another important manufacturing equipment, following machine tools due to their large working space and other advantages. Affected by geometric and compliance errors, robotic machining errors are very large, significantly impacting the application of robotic machining in scenarios that …

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Erbium Determination in Wrought Aluminum Alloys via Inductively Coupled Plasma Optical Emission Spectrometry

Pan Liu, Jianhao Zhang, Xiaodong Yuan, Yi Zhang et autres

Abstract Erbium-containing advanced aluminum alloys, such as 5E61, 5E83 and 7E75, have received widespread attention aluminum industrial chains due to their better comprehensive performance, including strength, plasticity, heat resistance and corrosion resistance. Then a rapid quantitative requirement for erbium content with a …

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Determination of manganese, chromium, nickel, molybdenum, tungsten, and copper in high manganese austenitic low-temperature steel by inductively coupled plasma atomic emission spectrometry

Jianhao Zhang, Pan Liu, Yi Zhang, Qianqian Chen et autres

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Exploring potential circRNA biomarkers for cancers based on double-line heterogeneous graph representation learning

Yi Zhang, ZhenMei Wang, Hanyan Wei, Min Chen

BACKGROUND: Compared with the time-consuming and labor-intensive for biological validation in vitro or in vivo, the computational models can provide high-quality and purposeful candidates in an instant. Existing computational models face limitations in effectively utilizing sparse local structural information for accurate predictions …

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m6A-modified circARHGAP12 promotes the aerobic glycolysis of doxorubicin-resistance osteosarcoma by targeting c-Myc

Dawei Zhang, Qingzhu Guo, Kemin You, Yi Zhang et autres

Abstract Chemotherapy resistance accompanied by energy metabolism abnormality functions as one of the main reasons for treatment failure and poor prognosis. However, the function of N6-methyladenosine (m6A)-modified circular RNA (circRNA) on osteosarcoma (OS) is still unclear. Here, present research investigated the potential …

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Identification of urinary volatile organic compounds as a potential non-invasive biomarker for esophageal cancer

Qi Liu, Shuhai Li, Yaping Li, L.‐C. YU et autres

Early diagnosis of esophageal cancer (EC) is extremely challenging. The study presented herein aimed to assess whether urinary volatile organic compounds (VOCs) may be emerging diagnostic biomarkers for EC. Urine samples were collected from EC patients and healthy controls (HCs). Gas chromatography-ion …

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Volatile organic compounds for early detection of prostate cancer from urine

Qi Liu, Yingjing Fan, Shunjie Zeng, Yuxiao Zhao et autres

Prostate cancer (PCa) is one of the most common cancers in men worldwide. Early diagnosis of PCa is extremely challenging due to the lack of effective diagnostic methods. The study presented here aims to evaluate whether urine volatile organic compounds (VOCs) can …

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Intergenic CircRNA Circ_0007379 Inhibits Colorectal Cancer Progression by Modulating miR-320a Biogenesis in a KSRP-Dependent Manner

Fei Long, Li Liang, Canbin Xie, Min Ma et autres

Circular RNAs (circRNAs) are covalently closed RNA structures that play multiple roles in tumorigenesis and progression.Compared with exon-intron circRNAs, the biological functions and implications of intergenic circRNAs in human cancer are still poorly understood.Here, we performed circRNA microarray analysis and identified an …

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