Li Chen

Nonzero-sum game-based online off-policy approximate optimal control of modular robotic manipulator system via data-driven method

Bo Dong, Li Chen, Bing Ma, Jingkai Liang et autres

This paper proposes a data-driven online off-policy approximate optimal control method within a nonzero-sum game framework for trajectory tracking tasks in modular robotic manipulator systems. To address the problem of partially inaccessible system dynamics, a data-driven neural network identifier is constructed to …

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Servo-Elastic Control of a Flexible Airship with Multiple Vectored Propellers

Li Chen, Lu Huang, Jie Lin

Owing to its large flexible envelope, an airship is highly sensitive to environmental disturbances, such as wind gusts. Fluid–structure interaction induces structural deformation, which modifies the aerodynamic force distribution and introduces additional coupling effects. Furthermore, servo-elastic deformation alters the position and orientation …

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Topology optimization and performance simulation of the transition zone of the proton exchange membrane fuel cell flow field

Zhuo Zhang, Yang Wang, Qi-Wei Luo, Qu Yang et autres

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Phenylbutene and Phenylpropanoid Constituents From Zingiber montanum and Their Anti‐Inflammatory Activity in Macrophages

Zhi‐Hang Wu, Li Chen, J. Y. Zhao, S. F. Yu et autres

Seventeen compounds, including seven undescribed compounds named Zingiberenes A-G (1-7), were isolated from the traditional medicinal plant Zingiber montanum. Their planar structures and absolute configurations were established by comprehensive spectroscopic analysis and ECD calculations. Evaluation of anti-inflammatory activity in LPS/IFN-γ-stimulated RAW264.7 macrophages …

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Resource Heterogeneity-Aware and Utilization-Enhanced Scheduling for Deep Learning Clusters

Abeda Sultana, Nabin Pakka, Fan Xu, Xu Yuan et autres

Scheduling deep learning (DL) models to train on powerful clusters with accelerators like GPUs and TPUs, presently falls short, either lacking fine-grained heterogeneity awareness or leaving resources substantially under-utilized. To fill this gap, we propose a novel task-level heterogeneity-aware scheduler for DL …

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Theoretical frontiers of in-situ rock mechanics under multi-physics-phase coupling in deep exploration of fluidized coal mining

Hongwei ZHOU, Ru Zhang, Dongjie Xue, Cunbao LI et autres

As shallow energy resources on Earth are progressively depleted, enhancing the capability to extract deep coal resources has become an inevitable trend in global scientific frontiers and technological development, as well as a strategic choice to ensure China’s long-term energy security. The …

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Model Whisper: Steering Vectors Unlock Large Language Models' Potential in Test-time

Xinyue Kang, Li Chen

It is a critical challenge to efficiently unlock the powerful reasoning potential of Large Language Models (LLMs) for specific tasks or new distributions. Existing test-time adaptation methods often require tuning model parameters, which is not only computationally expensive but also risks degrading …

Nicotine Activates PI3K/AKT Pathway to Induce Cellular Proliferation, Invasion, and Migration in HPV‐16 Positive Cervical Cancer SiHa Cells

Juan Wang, Yuxin Hu, Jin Sung Gong, Li Chen et autres

Nicotine exerts a substantial influence on cervical carcinogenesis by affecting the malignant progression of human papillomavirus (HPV)-18 positive and HPV-negative cervical cancer cells, as well as HPV-immortalized cervical epithelial cells. Further research is needed to fully elucidate the impact of nicotine on …

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PFOS effects on root stem cell maintenance and regeneration by suppressing the stem cell factor PLT2

Chenglin Wang, Chan Sun, Ke Ning, Shan He et autres

Perfluorooctane sulfonic acid (PFOS), a persistent organic pollutant, poses significant environmental risks due to its widespread contamination of agricultural systems. However, its phytotoxic mechanisms on Arabidopsis root growth and regeneration remain incompletely understood. In this study, we systematically investigated PFOS phytotoxicity and …

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The Influence of the External Chemistry of Silica-Based Mesoporous Nanocarriers on Organ Tropism and the Inhibition of Pulmonary Metastases

Wenping Ye, Yakai Yan, Li Chen, Zhongrui Yang et autres

Background: Mesoporous silica nanoparticles (MS NPs) have attracted significant interest for their role in the advancement of drug delivery systems. However, further investigation is needed to unravel the mechanisms behind the shift in organ tropism that occurs with changes in composition. Methods: …

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Patch-as-Decodable-Token: Towards Unified Multi-Modal Vision Tasks in MLLMs

Yongyi Su, Haojie Zhang, Shijie Li, Nanqing Liu et autres

Multimodal large language models (MLLMs) have advanced rapidly in recent years. However, existing approaches for vision tasks often rely on indirect representations, such as generating coordinates as text for detection, which limits performance and prevents dense prediction tasks like segmentation. To overcome …

Phase-separated NDF−FACT condensates facilitate transcription elongation on chromatin

Ziwei Li, Francesca Burgos‐Bravo, Kevin Xu, Li Chen et autres

How the facilitates chromatin transcription (FACT) complex enables RNA polymerase II to overcome chromatin barriers in cells remains poorly understood-especially given the limited direct interactions of FACT with polymerases, DNA or nucleosomes. Here we demonstrate that phase separation, mediated by nucleosome destabilizing …

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