Jiaxin Wang

A Temporally Programmed Microneedles Platform for Long‐Acting Regulation and Rapid Sensing of Systemic Copper Dyshomeostasis

Xu‐Wei Qi, Ya‐Hui Chen, Ye-Tao Zhang, Jing Li et autres

ABSTRACT Developing a minimally invasive platform capable of simultaneously enabling long‐acting copper metabolism regulation and rapid copper sensing remains a critical unmet challenge in addressing systemic copper dyshomeostasis. Here, we report a temporally programmed dual‐module microneedles platform integrating bio‐inspired nanosponges (BQMNPs) as …

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Global and regional prevalence, temporal trends, and projected trends of stroke after left ventricular assist device implantation: a systematic review and meta-analysis of 132,869 patients from 16 countries

Chao Wan, Meng‐Wei Ge, Wenhua Li, Lu-Ting Shen et autres

INTRODUCTION: Stroke after left ventricular assist device (LVAD) implantation is a serious complication in patients receiving LVAD treatment. This study aims to estimate the global and regional prevalence, temporal trends, and projected trends of post-LVAD stroke. METHODS: This study compiled literature on …

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Atmospheric Fate of n -Propyl Nitrate: Unraveling • OH-Initiated Oxidation Pathways, Kinetics, and Subsequent Degradation Mechanisms

Yun Ye, Peng Wang, Tai-Xing Chi, Jiaxin Wang et autres

N -propyl nitrate (NPN, CH 3 CH 2 CH 2 ONO 2 ), a prevalent atmospheric alkyl nitrate (RONO 2 ), is a key component of secondary organic aerosol (SOA) and a critical NO x reservoir. To support atmospheric pollution control, its …

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MOTS-c attenuates hyperoxia-induced neonatal cardiac injury by inhibiting oxeiptosis via maintaining the KEAP1-PGAM5 interaction

Shu-hong Li, Shi-qi Chen, Tao Lu, Jia-hao Wang et autres

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Reutilization of berry by-products for green food additives: a comprehensive review and future perspectives

Hao‐Yu Xue, Xiao‐Lin Yu, Fa-Lin Sun, Nuo Wang et autres

This paper reviews research from 2020 to 2026 on the applications of berry by-products. Based on their compositional profiles, it summarizes recent advances in extraction and processing technologies, with a focus on their potential as natural food additives. The role of artificial …

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Desensitization Induced by Alternating Layered Stacking: Structure–Property Correlation in CL-20/DMDNP Cocrystals

Cong Li, Zujia Lu, Chao Zhang, Mei-Qi Xu et autres

The pursuit of high-energy-density materials (HEDMs) with low mechanical sensitivity remains a paramount challenge in energetic materials science. This study addresses this challenge through the rational design and synthesis of a novel cocrystal formed between the powerful explosive CL-20 and the insensitive …

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Fibroblast-Mediated MMP2 Contribution to Nonresponse in Anti-TNFα Therapy for Crohn’s Disease

Danshu Wang, Dehao Zhu, Xiangyu Zhao, Jiaxin Wang et autres

BACKGROUND: Despite the transformative impact of biologics on the treatment of inflammatory bowel disease (IBD) in recent years, a substantial proportion of patients remain unresponsive to these advanced therapies. Overcoming resistance remains a significant clinical challenge, largely due to the incomplete understanding …

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Integrating network pharmacology, molecular docking and experimental verification to explore the protective effect of Buyang Huanwu Decoction on cerebral ischemic stroke

Yixuan Guo, Wenqian Liu, Bei Qi, Ziyi Liu et autres

Cerebral ischemic stroke (CIS), the most prevalent form of stroke worldwide, exerts substantial impacts on both public health and socioeconomic conditions, particularly among elderly populations. Buyang Huanwu Decoction (BYHWD) has been recognized as a representative herbal formula for the management of ischemic …

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The Influence of Intramolecular C═C Number on the ESIPT Reactions of HBTM Derivatives: A Theoretical Study

Zhiqiang Chen, Yu Yang, Xiaofei Tan, Jiaxin Wang et autres

In the work, theoretical calculations were utilized to explore how the count of intramolecular double bonds influences the excited-state intramolecular proton transfer (ESIPT) reaction in HBTM derivatives. Three derivatives, namely, HBTM-1 (HBTM: 4-methyl-2-benzothiazolyl-6-pyrimidine vinylphenol), HBTM-2, and HBTM-3, were designed, and their geometric …

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Zhichi Suanzaoren Decoction alleviates perimenopausal insomnia via restoring astrocytic primary cilia and modulating Wnt/GSK-3β/GR signaling axis

Zeyu Zhang, Yufei Liu, Boyang Zhao, Hongxin Fu et autres

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Decoding TRON: A Comprehensive Framework for Large-Scale Blockchain Data Extraction and Exploration

Qian’ang Mao, Jiaxin Wang, Yi Zhang, Jiaqi Yan

Cryptocurrencies and Web3 applications based on blockchain technology have flourished in the blockchain research field. Unlike Bitcoin and Ethereum, due to its unique architectural designs in consensus mechanisms, resource management, and throughput, TRON has developed a more distinctive ecosystem and application scenarios …

Deciphering the enzymatic responses, composition, network complexity, and functional degraders of the marine sediment bacterial community in response to 2-methyl-4-isothiazoline-3-one exposure

Jingwei Wang, Jiaxin Wang, Shuzhen Li, Xuwang Zhang et autres

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