Guoping Wang

Amyloid-β precursor protein promotes tumor growth by establishing an immune-exclusive tumor microenvironment

Tao Yin, Guoping Wang, Zhehao Ma, Liuyang Wang et autres

Abstract During initiation and progression, cancerous tissue hijacks a series of elaborate tissue homeostatic mechanisms to avoid immune surveillance, including neuro-immune interactions. Here, we show that amyloid-β precursor protein (APP) and its β-cleavage product amyloid-β1-42 (Aβ1-42), well-known in the pathogenesis of Alzheimer’s …

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Changes in tear cytokine and lactoferrin levels in postmenopausal women with primary acquired nasolacrimal duct obstruction complicated with obstructed meibomian gland dysfunction

Haili Jin, Xianjie Chen, Feng Ji, Yin Liu et autres

BACKGROUND: Epiphora and secondary ocular surface damage are increasingly impairing the quality of life of people, particularly elderly women. We aimed to investigate the changes in tear cytokine and lactoferrin levels in postmenopausal women with primary acquired nasolacrimal duct obstruction (PANDO) complicated …

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Author response for "Dexamethasone-loaded fibroin nanoparticles promote retinal reattachment in rats by regulating the Th17/Treg balance"

Linfeng Han, Xiaomeng Li, Genjie Ke, Kai Dong et autres

Author response for "Dexamethasone-loaded fibroin nanoparticles promote retinal reattachment in rats by regulating the Th17/Treg balance"

Linfeng Han, Xiaomeng Li, Genjie Ke, Kai Dong et autres

Aberrant cytoplasmic expression of UHRF1 restrains the MHC-I-mediated anti-tumor immune response

Lianmei Tan, Tao Yin, Handan Xiang, Liuyang Wang et autres

Immunotherapy successfully complements traditional cancer treatment. However, primary and acquired resistance might limit efficacy. Reduced antigen presentation by MHC-I has been identified as potential resistance factor. Here we show that the epigenetic regulator ubiquitin-like with PHD and ring finger domains 1 (UHRF1), …

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Neurotrophic keratitis caused by lightning injury: a case report

Sidou Yi, Guoping Wang, Xuan Meng, Xuejing Lu

BACKGROUND: This study aimed to report a case of neurotrophic keratitis caused by lightning. CASE PRESENTATION: A 38-year-old man was hit by lightning and suffered eye injury. He eventually developed neurotrophic keratitis. RESULTS: The patient's injury history and burn site were analyzed, …

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Dominantly Inherited Alzheimer Network Trials Unit (DIAN-TU): Trial Satisfaction and Attitudes towards Future Clinical Trials

Haiyan Liu, Jonathan C. Li, Ellen Ziegemeier, Sarah Foster Adams et autres

BACKGROUND: Clinical trial satisfaction is increasingly important for future trial designs and is associated with treatment adherence and willingness to enroll in future research studies or to recommend trial participation. In this post-trial survey, we examined participant satisfaction and attitudes toward future …

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Reply to Comment on “Association Between Physical Indicators and Myopia in American Adolescents: National Health and Nutrition Examination Survey 1999-2008”

Ninghong Chen, Yonghong Sheng, Guoping Wang

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Trend analysis and prediction of the incidence and mortality of CKD in China and the US

Wenpeng Zhu, Mengqi Han, Yuxin Wang, Guoping Wang

BACKGROUND: Currently, limited research is available on the comparative analysis of chronic kidney disease (CKD) incidence and mortality rates between China and the United States. This study aimed to explore the trends in CKD incidence and mortality rates in both countries, as …

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Recurrence of macular edema in patients with branch retinal vein occlusion: a proteomic study

Yin Liu, Xiaohu Wang, Yonghong Sheng, Haili Jin et autres

BACKGROUND: Branch retinal vein occlusion (BRVO) is a common retinal vascular disease leading to severe vision loss and blindness. This study aimed to investigate and reveal the pathophysiological mechanisms underlying macular edema (ME) recurrence in patients with BRVO through a proteomic approach. …

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Higher incidence of meibomian gland dysfunction in postmenopausal women with primary acquired nasolacrimal duct obstruction

Guoping Wang, Haili Jin, Yonghong Sheng, Feng Ji et autres

PURPOSE: This study aimed to investigate the incidence of meibomian gland dysfunction (MGD) in postmenopausal women with primary acquired nasolacrimal duct obstruction (PANDO) and enables ophthalmologists to pay attention to ocular surface damage before surgery. METHODS: 165 postmenopausal women with PANDO and …

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Trend analysis and prediction of the incidence and mortality of CKD in China and the US

Wenpeng Zhu, Mengqi Han, Yuxin Wang, Guoping Wang

Abstract Purpose Currently, limited research is available on the comparative analysis of chronic kidney disease (CKD) incidence and mortality rates between China and the United States. This study aimed to explore the trends in CKD incidence and mortality rates in both countries, …

cn (code pays fourni par la source)