Jun Li

Single cell multi-omics guided hydrogel enables closed-loop therapy for renal osteodystrophy

Lei Fan, Kenan Sun, Feiping Xia, Guanghong Wu et autres

Fracture repair in renal osteodystrophy remains challenging because impaired bone quality compromises fixation stability, while current systemic therapies regulating bone metabolism do not sufficiently address the disease-specific mechanisms underlying defective repair. An integrated strategy combining early fracture stabilization with mechanism-guided local treatment …

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A strategy of 3D-printed Ta4C3 MXenes nanohydroxyapatite/methacryloylated silk fibroin scaffolds for postsurgical management of osteosarcoma

Liu Yang, Kenan Sun, Deng Shihao, Shuai Liang et autres

The postoperative repair of bone tumors remains a significant clinical challenge requiring urgent solutions, and this holds particularly true for regenerating large bone defects, completely removing residual tumor cells, and effectively preventing and controlling postoperative infections. The efficacy of traditional single treatments …

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Total hip arthroplasty and perioperative management of a patient with hip osteonecrosis secondary to hypopituitarism due to Sheehan syndrome: a case report and literature review

Biao Ma, Jun Li, Tao Ma, He Shang et autres

Background: Sheehan's syndrome, a rare disorder resulting from postpartum hemorrhage-induced necrosis of the anterior pituitary gland, necessitates long-term hormone replacement therapy with glucocorticoids. This predisposes patients to severe complications, including rapid-progression osteonecrosis of the femoral head (ONFH), which carries a high disability …

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Case Report: Prosthetic revision due to aseptic loosening following total knee arthroplasty: a clinical management and pathological mechanism investigation

Jun Li, He Shang, Tao Ma, Tianxiang Yang et autres

Background: Total joint arthroplasty is an effective treatment for end-stage joint diseases, with approximately 1.5 million procedures performed globally annually and a 25%-30% annual growth rate in China. However, 10%-15% of patients develop prosthetic loosening or subsidence within 15-20 years postoperatively, predominantly …

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Radial extracorporeal shock wave therapy alters plantar pressure distribution in chronic plantar fasciitis: a biomechanical analysis

He Shang, Tao Ma, Yuan Wei, Tianxiang Yang et autres

Objective This study aimed to investigate the impact of radial extracorporeal shockwave therapy (rESWT) on plantar pressure distribution in patients with chronic plantar fasciitis (PF). While prior research has established rESWT's clinical efficacy in pain relief, its specific biomechanical effects on plantar …

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Comparative efficacy of the modified minimally invasive “Parachute Technique” vs. the intermuscular GAP Approach in proximal humeral fracture management: a prospective study

Jianhua Wei, Jun Li, Tao Chen, Hao Yi et autres

Background Proximal humeral fractures (PHFs) are common in elderly individuals, often resulting from osteoporosis and falls. Surgical intervention is required for displaced fractures to restore shoulder function. This study compares the Modified Minimally Invasive Parachute Technique and the Intermuscular Gap Approach in …

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Comparative Efficacy of the Modified Minimally Invasive “Parachute Technique” Versus the Intermuscular Gap Approach in Proximal Humeral Fracture Management: A Prospective Study

Jun Li, Tao Chen, Hyeong-Joong Yi, Wentao Zhao et autres

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Multifidus fat infiltration negatively influences the postoperative outcomes in lumbar disc herniation following transforaminal approach percutaneous endoscopic lumbar discectomy

Kai Sun, Renjie Qin, Wenzhuo Wang, Genlong Jiao et autres

PURPOSE: This study aims to investigate the influence of multifidus muscle fat infiltration on clinical outcomes in lumbar disc herniation (LDH) undergoing percutaneous endoscopic lumbar discectomy (PELD). METHODS: A retrospective analysis was conducted on 224 patients who underwent lateral PELD, with complete …

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Comparison of clinical outcomes of bilateral and unilateral unicompartmental knee arthroplasty for the treatment of knee osteoarthritis

Hao Yu, Jia Li, Jun Li, Feng Zhao et autres

The risks and benefits associated with simultaneous bilateral unicompartmental knee arthroplasty (UKA) continue to engender contentious debate. The aim of this study was to compare the clinical outcomes of simultaneous bilateral and unilateral UKA. A retrospective review was performed between 2019 and …

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Efficacy of Percutaneous Kyphoplasty and Percutaneous Pedicle Screw Fixation in Managing Osteoporotic Vertebral Compression Fractures in Middle-Aged and Elderly Individuals: A Comparative Study

Jun Li, Wenbin Zhou, Jiansheng Chen, Xian Tao

AIM: This study is aims to compare the clinical efficacy and safety of percutaneous kyphoplasty (PKP) and percutaneous pedicle screw fixation (PPSF) in managing osteoporotic vertebral compression fractures (OVCFs) among middle-aged and elderly individuals. METHODS: A total of 142 patients aged 55-65 …

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Comparison of the effects of high tibial osteotomy with and without a tourniquet

Huiwen Wu, Fangyuan Wang, Shihao Deng, Shuai Liang et autres

BACKGROUND: Tourniquets are routinely employed to achieve hemostasis in modern limb surgeries. Nevertheless, the precise role and benefits of tourniquets in high tibial osteotomy (HTO) surgeries remain understudied. The aim of this study was to assess the application of tourniquets in high-tibial …

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Comparative clinical efficacy of percutaneous coaxial large-channel endoscopic lumbar interbody fusion and transforaminal lumbar interbody fusion for degenerative lumbar spinal stenosis: a retrospective study

Zige Liu, Tianxiang Yang, Jun Li, Desheng Chen

This study aimed to evaluate the clinical efficacy of percutaneous coaxial large-channel endoscopic lumbar interbody fusion (PCLE-LIF) and transforaminal lumbar interbody fusion (TLIF) in the treatment of degenerative lumbar spinal stenosis. The clinical data of patients with degenerative lumbar spinal stenosis who …

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