Accès ouvert
2026
review
OpenAlex
Shengnan Li, Tengfei Chen, Hongyan Chen, 高博贤 et autres
Male infertility (MI) represents a complex clinical issue affecting millions of couples worldwide. Its diverse etiologies and incompletely elucidated mechanisms limit the development of effective therapeutic strategies. Animal models, serving as a bridge between basic research and clinical practice, play an indispensable …
cn
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Accès ouvert
2026
article
OpenAlex
Ye Yuan, Minghui Wang, Mingyue Hao, Jialu Chen et autres
Brucella is a Gram-negative facultative intracellular pathogen that causes widespread zoonotic infections. Macrophages are crucial immune and antigen-presenting cells that differentiate into proinflammatory M1-type or anti-inflammatory M2-type cells in different microenvironments. The BtpB protein of Brucella is a type IV secretion system …
Tunisie, cn
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Accès ouvert
2026
article
OpenAlex
Ye Yuan, Minghui Wang, Mingyue Hao, Jialu Chen (2939340) et autres
Additional file 2. Primers used in this study.
cn
(code pays fourni par la source)
Accès ouvert
2026
other
OpenAlex
Ye Yuan, Minghui Wang, Mingyue Hao, Jialu Chen (2939340) et autres
Additional file 1. Validation of inhibitor treatment and overexpression. (A) CCK8 screening for Stattic concentration. (B) Inhibitory effect of Stattic on STAT3 detected by qPCR. (C) PCR amplification of stat3 gene. (D) Fluorescence detection of pEGFP-C1-STAT3 vector transfection efficiency. (E) Western blot …
cn
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Ye Yuan, Minghui Wang, Mingyue Hao, Jialu Chen (2939340) et autres
Additional file 2. Primers used in this study.
cn
(code pays fourni par la source)
Accès ouvert
2026
other
OpenAlex
Ye Yuan, Minghui Wang, Mingyue Hao, Jialu Chen (2939340) et autres
Additional file 1. Validation of inhibitor treatment and overexpression. (A) CCK8 screening for Stattic concentration. (B) Inhibitory effect of Stattic on STAT3 detected by qPCR. (C) PCR amplification of stat3 gene. (D) Fluorescence detection of pEGFP-C1-STAT3 vector transfection efficiency. (E) Western blot …
cn
(code pays fourni par la source)
Accès ouvert
2026
review
OpenAlex
Shengnan Li, Tengfei Chen, 高博贤, Chongfu Zhong
Background Varicocele is a common correctable cause of male infertility, and antisperm antibodies (ASA) have been detected at varying rates in affected men. However, the effect of varicocele repair on ASA positivity remains controversial, and no meta-analysis has specifically quantified this outcome …
cn
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2025
letter
OpenAlex
Shengnan Li, Yiheng Yao, Liang Liu
The data that support the findings of this study are available on request from the corresponding author. The data are not publicly available due to privacy or ethical restrictions.
cn
(code pays fourni par la source)
2025
article
OpenAlex
Yiheng Yao, Shengnan Li, Qing Shui Yin, Liang Liu
Data sharing not applicable to this article as no datasets were generated or analysed during the current study.
cn
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Accès ouvert
2025
article
OpenAlex
Shengnan Li, Wenkui Zhang, Wenzhong Shi, Yan Zhang et autres
ABSTRACT Obesity involves persistent inflammation, insulin resistance, and disturbances in gut microbiota. Achyranthes bidentata , a plant long used in Chinese medicine, contains polysaccharides with bioactive properties. This study investigates polysaccharides isolated from its water extract (ABPs) consisting of 41.83% Glucose, 40.75% …
cn
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Accès ouvert
2025
article
OpenAlex
Zhan Yu Pan, Dejun Cun, Wenjing Wang, Jingyu Zhao et autres
Frailty and diabetes mellitus (DM) are closely linked, but their causal relationship remains unclear. This study aims to determine the bidirectional causal relationship between frailty and different DM subtypes using Mendelian randomization (MR). We performed a 2-sample MR analysis using summary statistics …
cn, hk
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Accès ouvert
2025
article
OpenAlex
Le Huang, Hua Li, Weitao Yang, Lihui Huang et autres
. In gestational obesity mice, LTA administration reduced weight gain, visceral/gonadal adiposity, metabolic markers (fasting glucose/insulin/cholesterol), gut barrier dysfunction (TNF-α, IL-6, IL-8, Claudin-2), and linked to FXR/FGF15 pathway alterations. Furthermore, LTA intervention suppressed MCP-1, IL-1β, F4/80 and hepatic lipid metabolism regulators (CD36, …
cn
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