Yun Zhang

Structural Airworthiness and Mechanical Characteristics Analysis of Real-Time Flight Data Acquisition Equipment

Xiaodong Xu, Jianwei Gao, Qiang Guo, Yun Zhang et autres

The rising complexity of civil aviation and recent incidents, including Sichuan Airlines “14 May” and China Eastern Airlines “21 March,” highlight the urgent need for real-time flight data acquisition systems to support timely safety monitoring and early warning. Current methods rely mainly …

Folate-ClipTAC: Design and Proof of Concept Study

Xueyan Cao, Meiying Quan, Yun Zhang, Qingyang Chen et autres

OBJECTIVE: Proteolysis-targeting chimaeras (PROTAC) technology is a rapidly emerging and intensively investigated strategy in the field of new drug research and development. However, due to the tripartite structure of PROTAC molecules, their molecular weights are generally high, which results in poor cell …

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Single‐Atom Control of Aromaticity and Excited‐State Dynamics in Endohedral Zirconium–Antimony Zintl Clusters

Yun Zhang, Ziqi Deng, Wen‐Juan Tian, Huiqing Sun et autres

ABSTRACT Three‐dimensional (3D) aromaticity provides a powerful framework for understanding the stability and electronic structures of superatomic clusters, yet how such aromaticity evolves during atom‐by‐atom structural growth remains poorly understood. Herein, we report two endohedral zirconium‐antimony Zintl clusters, [Zr@Sb 12 ] 2− …

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Enhancing SiCf/SiC Composite Fabricated by PIP Process with In-situ Formed SiC Nanowires

Luke Ma, Weiye Xu, Yun Zhang, Xueliang Pei et autres

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Discovery of novel METTL3 inhibitors: design, synthesis, and in silico and in vitro evaluations

Yun Zhang, Mengyan Chen, Yanwen He, Qinlan Chen et autres

value of 980.3 nM, significantly better than Genistein (37.31% inhibition at 40 µM). Molecular docking revealed that H1's binding mode was similar to STM2457, forming hydrogen bonds and hydrophobic interactions within the METTL3 pocket. Druglikeness prediction by SwissADMET and ADMETlab 3.0 showed …

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Correction: Discovery of novel METTL3 inhibitors: design, synthesis, and in silico and in vitro evaluations

Yun Zhang, Mengyan Chen, Yanwen He, Qinlan Chen et autres

Correction for ‘Discovery of novel METTL3 inhibitors: design, synthesis, and in silico and in vitro evaluations’ by Yun Zhang et al. , RSC Adv. , 2026, https://doi.org/10.1039/d6ra02851a.

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Microwave co-pyrolysis of metallurgical dust and corn straw for magnetic biochar toward wastewater treatment

Xiaolei Ye, Ming Hou, Lei Gao, Yi Xia et autres

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Molecular diagnosis of suspected intestinal schistosomiasis in a non-endemic area of Yunnan Province, China

Shiyuan Wu, Chunhong Du, Jihuang Yang, Fang Lin Luo et autres

BACKGROUND: While Schistosoma japonicum is endemic in the Yangtze River Basin and parts of Yunnan and Sichuan provinces in China, Mangshi City in Dehong Prefecture, Yunnan Province, is not recognized as an endemic area. Between 1996 and 2018, more than 20 suspected …

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A method for predicting random vibration response of train-track-bridge system based on GA-BP neural network

Jianfeng Mao, Yun Zhang, Zheng Li, Mansoor A. Khan et autres

To enhance the efficiency of stochastic vibration analysis for the train-track-bridge (TTB) coupled system, this paper proposes a prediction method based on a Genetic Algorithm-optimized Backpropagation (GA-BP) neural network. First, initial track irregularity samples and random parameter sets of the vehicle–bridge system(VBS) …

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PROTACs in Antivirals: Current Advancements and Future Perspectives

Jiacheng Jin, Meiying Quan, Xueyan Cao, Yun Zhang et autres

Proteolysis-targeting chimera (PROTAC) technology has demonstrated remarkable progress in tumor therapy, attributed to its unique capability of catalytically degrading "undruggable" targets. In the context of the ongoing global health threat posed by the Coronavirus Disease 2019 (COVID-19) pandemic, the application scope of …

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Photochromic Cu-TiO2 Nanocatalysts for Visible-Light-Triggered C−Cl Activation and Selective Molecular Assembly

Chaowei Han, Yun Zhang, Lulu Fu, Lili Xu et autres

The efficient photoactivation of C−Cl bonds to selectively form C−C and C−O bonds via cross-coupling has emerged as a promising strategy for photosynthesizing pharmaceuticals. However, achieving selective cross-coupling of unactivated C−Cl bonds using visible light in a photoredox system remains a formidable …

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Emerging mechanisms and implications of m6A in CVDs: potential applications of natural products

Hui Wang, Yun Zhang, Xiao Yu Jiang, Guichun Liu et autres

N6-methyladenosine (m6A) RNA methylation is the most common, abundant, and reversible epigenetic modification of RNAs, and it directs many essential processes in RNAs post-transcriptionally. It has been shown that m6A modification affects cardiovascular diseases (CVDs) by regulating RNA splicing, localization, translation, and …

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